Hydroxyzine: Uses, Side Effects, Storage and Precautions
Written by Medicover Team and Medically Reviewed by Dr Siva Anoop Yella, Psychiatry
Vistaril (Hydroxyzine) is a type of allergy medicine that also helps you feel calm and relaxed. It is often used to reduce anxiety and stress, and sometimes, it is given before surgery along with other medicines to help with anesthesia. Vistaril can also help control nausea and vomiting, and it is used to treat skin allergies, such as hives or rashes. It is also available as a generic medicine.
Hydroxyzine is an antihistamine with both sedative and anti-anxiety properties. It comes in two forms: hydroxyzine hydrochloride and hydroxyzine pamoate. These forms are used interchangeably depending on the condition being treated. It works by affecting certain natural substances (histamine and serotonin) in the body and brain to reduce symptoms like itching, anxiety, and nausea.
Hydroxyzine provides relief in a variety of conditions. It is commonly used for:
Hydroxyzine works by blocking histamine H1 receptors in the body, which reduces allergic reactions. It also affects neurotransmitters, such as serotonin, in the brain, helping to reduce anxiety and promote sleep. Unlike benzodiazepines, Hydroxyzine does not have the risk of dependence, making it a safer option for many patients.
The dosage of Hydroxyzine depends on the patient's age, condition, and response to treatment. It is typically taken by mouth or injected as prescribed by a doctor for managing anxiety, allergies, or sleep disorders.
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed one-do not take a double dose.
Symptoms of hydroxyzine overdose may include extreme drowsiness, nausea, vomiting, confusion, and, in severe cases, seizures or difficulty breathing. Seek immediate medical attention if an overdose is suspected.
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Get Second OpinionHydroxyzine may cause drowsiness, dry mouth, dizziness, or headache. Most side effects are mild, but if any become bothersome or severe, please consult your doctor.
Consult your doctor if any symptoms persist or worsen.
Before taking Hydroxyzine, let your doctor know if you have heart issues, breathing problems, or are pregnant or breastfeeding. Caution is also advised in older adults and people with liver or kidney problems.
Hydroxyzine may be prescribed to children, but dosing is adjusted. Elderly patients may need lower doses due to increased sensitivity.
Hydroxyzine can interact with other medications that cause drowsiness, such as alcohol, sedatives, or antihistamines. Always inform your doctor about any other drugs or supplements you are taking.
Exposure to heat, moisture, or light can reduce the effectiveness of the medication. Expired or improperly stored Hydroxyzine should not be used.

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040-68334455Vistaril (hydroxyzine) is used to treat anxiety and tension. It is also prescribed to relieve itching caused by allergies and to induce sedation prior to medical procedures.
Atarax and Vistaril both contain hydroxyzine but are different formulations. Atarax is hydroxyzine hydrochloride, while Vistaril is hydroxyzine pamoate.
Vistaril can start working within 30 minutes to an hour for anxiety relief. Its calming effects may be felt relatively quickly compared to other medications.
No, Vistaril (hydroxyzine) and Benadryl (diphenhydramine) are different medications, although both are antihistamines. Vistaril is primarily used for anxiety and sedation, while Benadryl is used for allergy relief.
Hydroxyzine is not typically classified as a strong sleeping pill but can be effective for inducing sleep due to its sedative properties. It is more commonly used for anxiety and allergy-related symptoms.
Hydroxyzine is generally safe when used as prescribed, but it can cause side effects like drowsiness or dizziness. Always use it under medical supervision, especially if you have underlying health conditions.
You should avoid taking hydroxyzine with alcohol or other central nervous system depressants, as it can enhance drowsiness and impair coordination. Additionally, be cautious with other medications that may interact, including certain antidepressants and sedatives.
Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.