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Piroxicam

Piroxicam

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By Medicover Hospitals / 05 April 2021
Home | Medicine | Piroxicam

Piroxicam

  • Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis and rheumatoid arthritis pain and inflammation. The medication is available as the brand-name drug called Feldene. NSAIDs are non-narcotic pain relievers that can be used for a number of conditions, including injury, menstrual cramps, arthritis, and other musculoskeletal problems. They function by lowering prostaglandin levels, which are the chemicals that cause pain, fever, and inflammation. Piroxicam inhibits the enzyme that produces prostaglandins (cyclooxygenase), resulting in lower prostaglandin concentrations.
    1. Piroxicam Uses
    2. Piroxicam Side effects
    3. Precautions
    4. Drug forms and strengths
    5. Dosage
    6. Warnings
    7. Storage
    8. Piroxicam vs Paracetamol
    9. Frequently Asked Questions
    10. Citations

    Piroxicam Uses:

  • Piroxicam is used to relieve arthritis-related discomfort, swelling, and stiffness. Reducing these symptoms allows you to participate in more of your everyday activities. This drug belongs to the class of drugs called nonsteroidal anti-inflammatory drug (NSAID). It works by preventing the development of certain natural substances that cause inflammation in your body.
  • Piroxicam Side Effects:

  • The most common side effects of Piroxicam are:
    • Rash
    • Headache
    • Dizziness
    • Drowsiness
    • Abdominal pain
    • Nausea
    • Fluid retention
    • Heartburn
  • Some of the serious side effects of Piroxicam are:
    • Swelling of face, lips or tongue
    • Chest pain
    • Shortness of breath
    • Heart attack
    • Unusual weight gain
    • Stomach pain
    • Vomiting blood
    • Blistering and peeling of the skin
  • Piroxicam can cause some serious side effects and can lead to some serious health problems. If you are facing any of the above serious side effects. Talk with your doctor if you are having any serious problems.
  • Precautions:

  • Before taking Piroxicam talk with your doctor if you are allergic to it or any other medications. The drug may contain some inactive ingredients which can cause serious allergic reactions or some other serious problems. Before using any drug consult with your doctor if you are having any medical history such as asthma, blood disorders, nasal polyps, heart disease, high blood pressure, liver disease, stroke, intestinal problems and heartburn.
  • Talk to your doctor if you are taking any prescriptions, non-prescription medications, vitamins, nutritional supplements and herbal products. If you have or have ever had asthma, tell your doctor, particularly if you still have a stuffy or runny nose, nasal polyps (swelling of the nose lining), heart failure, swelling of the hands, feet, ankles, or lower legs, or liver or kidney disease.
  • How to use Piroxicam?

  • Piroxicam comes in the form of capsules which should be taken orally. Mainly, the drug is taken once or twice a day. Try to take the drug at the same time every day. The medication will help you to control the symptoms but is unable to cure the condition. It can take 8 to 12 weeks or longer for showing the benefit of the medications.
  • Drug forms and strengths

  • Generic: Piroxicam
    • Form: oral capsule (10 mg and 20 mg)
  • Brand: Feldene
    • Form: oral capsule (10 mg and 20 mg)

    Dosage for osteoarthritis

  • Adult dosage (ages 18 years and older): 20 mg should be taken once per day i.e. 10 mg two times a day
  • Dosage for rheumatoid arthritis

  • Adult dosage (ages 18 years and older): 20 mg should be taken once per day i.e. 10 mg two times a day
  • Missed Dose

  • If you forget to take a dose, take it as soon as possible. If it’s time for your next dose then wait and take a single dose at your regular time. Never try to make up for missed doses by taking two at once. This can lead to some severe consequences.
  • Overdose

  • If you are taking too much excessive medication then there is a chance of getting some severe symptoms like fatigue, drowsiness, nausea, vomiting, stomach pain and stomach bleeding. In some rare cases taking too much of drugs can lead to allergic reactions, high blood pressure, kidney failure, trouble breathing and coma. Talk to your doctor immediately if you are having any serious medical conditions.
  • Warnings for serious Health Conditions:

  • For people with Asthma:
  • Asthma attacks can be triggered by piroxicam. It should not be used if you have asthma that is caused by aspirin. It's possible that it has the same impact as aspirin.
  • For people with ulcer or stomach bleeding:
  • This drug increases the chances of bleeding in your stomach or intestines. If you take piroxicam and have a history of ulcers, stomach or intestinal bleeding then try to avoid it for a certain period of time.
  • For people with Kidney disease:
  • If you take the medication for a long time, it can damage your kidneys. This medication should not be used if you have extreme kidney disease.
  • For people with High Blood Pressure:
  • The drug has the potential to trigger or exacerbate elevated blood pressure. When taking piroxicam, you may need to monitor your blood pressure often.
  • Pregnancy & Breastfeeding:
  • The drug should not be taken during the third trimester of pregnancy. It has the potential to endanger your pregnancy. If you're pregnant or planning to become pregnant, speak to your doctor.
  • The drug can pass through your breast milk and cause side effects in a breastfed infant. Breastfeeding is not advised while taking this drug.
  • Storage:

  • Direct contact with heat, air and light may damage your medicines.Exposure to medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach.
  • Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).
  • Piroxicam vs Paracetamol

    Piroxicam
    Paracetamol
    Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis and rheumatoid arthritis pain and inflammation. Paracetamol is a painkiller and works as a fever reducer. The paracetamol tablets are used for treating headaches, muscle aches, arthritis, backache, body ache and fevers.
    Piroxicam is used to relieve arthritis-related discomfort, swelling, and stiffness. Reducing these symptoms allows you to participate in more of your everyday activities. Paracetamol is used for the following treating the following diseases:
    • Headaches
    • Menstrual period
    • Toothaches
    The most common side effects of Piroxicam are:
    • Rash
    • Headaches
    • Dizziness
    • Drowsiness
    • Abdominal pain
    Some common side effects of paracetamol are:
    • Nausea
    • Vomiting
    • Swelling
    • Pain

    Frequently Asked Questions:

    Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis and rheumatoid arthritis pain and inflammation. This drug belongs to the class of drugs called nonsteroidal anti-inflammatory drugs (NSAID).
    Piroxicam is used for the treatment of pain or inflammation caused by osteoarthritis and rheumatoid arthritis.
    Piroxicam was given once a day at a dose of 20 mg, and ibuprofen was given three times a day at a dose of 400 mg. Both medications proved to be similarly successful, and patients taking either drug reported only mild side effects. Piroxicam has a distinct practical benefit over ibuprofen due to its once-daily administration.
    The most common side effects of Piroxicam are:
    • Rash
    • Headaches
    • Dizziness
    • Drowsiness
    • Abdominal pain
    Piroxicam has a strong tolerability profile and can effectively alleviate acute low-back pain. It should be considered for use in the initial treatment of this condition.
    Piroxicam is taken as a tablet orally, preferably with food to reduce the risk of stomach upset. This drug should take effect within 1 to 2 hours, and clinical signs should improve as a result.

    Citations:

  • Piroxicam, https://link.springer.com/article/10.2165/00003495-198428040-00002
  • Effects of Piroxicam, https://onlinelibrary.wiley.com/doi/abs/10.1002/art.1780360905