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Nitrofurantoin

nitrofurantoin
By Medicover Hospitals / 10 Mar 2021
Home | Medicine | Nitrofurantoin

What is Nitrofurantoin?

  • Nitrofurantoin is an antibiotic used to treat infections of the urinary tract caused by several bacteria. E. coli, Enterobacter cystitis, Enterococcus, Klebsiella, and Staphylococcus aureus are all susceptible to it. Nitrofurantoin inhibits the synthesis of proteins, DNA, and cell walls in bacteria. Bacteria cannot live or reproduce without the presence of a cell wall.
    1. Nitrofurantoin Uses
    2. Nitrofurantoin Side effects
    3. Precautions
    4. Overdose
    5. Warnings
    6. Storage
    7. Nitrofurantoin vs Doxycycline
    8. Frequently Asked Questions
    9. Citations

    Nitrofurantoin Uses:

  • This medicine is used to treat or avoid infections of the urinary tract. This drug is an antibiotic that works by preventing bacteria from growing. It is ineffective against viral infections (e.g., common cold, flu). Antibiotics may lose their efficacy if they are used excessively. Nitrofurantoin should not be administered to children under the age of one month because it can cause a blood disorder (hemolytic anaemia).
  • Nitrofurantoin Side Effects:

  • Some of the common side effects of Nitrofurantoin are:
    • Nausea
    • Vomiting
    • Loss of appetite
    • Stomach pain
    • Diarrhea
    • Numbness in the hand
    • Pain in the hands
    • Weakness
    • Dizziness
    • Headache
    • Drowsiness
  • Some of the serious side effects of Nitrofurantoin are:
    • Lung inflammation
    • Shortness in breath
    • Fever
    • Chills
    • Chest pain
    • Liver problems
    • Dark urine
    • Loss of appetite
  • Nitrofurantoin can cause some serious side effects and can lead to some serious health problems. If you are facing any of the above serious side effects. Talk with your doctor if you are having any serious problems.
  • Precautions:

  • Before taking Nitrofurantoin talk with your doctor if you are allergic to it or any other medications. The product may contain some inactive ingredients which can cause some serious allergic reactions or some other problems. Before using Nitrofurantoin talk with your doctor if you are having any medical history such as blood disorders kidney and liver disease lung diseases nerve problems. Eye diseases diabetes and vitamin B deficiency.
  • Nitrofurantoin can impair the effectiveness of live bacterial vaccines (such as the typhoid vaccine). If your doctor advises otherwise, do not get any immunizations or vaccines while taking this drug. Kidney function deteriorates as you age. The kidneys eliminate this drug. As a result, older adults may be more prone to side effects of this medication, especially nerve and liver problems.
  • How to use Nitrofurantoin?

  • Nitrofurantoin is available as a capsule and a liquid for oral administration. For at least 7 days, nitrofurantoin is normally taken two to four times a day. It should be taken with a full glass of water and meals. Take nitrofurantoin at the same time every day if possible. Follow the instructions on your prescription label closely, and if there is something you don't understand, ask your doctor or pharmacist to explain it to you.
  • Before each use, give the liquid a good shake to ensure that the drug is uniformly distributed. Do not use a household spoon to determine the proper amount of liquid for each dose; instead, use a dose-measuring spoon or cup. During the first few days of nitrofurantoin therapy, you should start to feel better. Contact your doctor if your symptoms do not change or if they worsen.
  • Forms and strengths:

  • Generic: Nitrofurantoin
    • Form: oral capsule (generic for Macrobid)
    • Strength: 100 mg (75 mg nitrofurantoin monohydrate and 25 mg nitrofurantoin macrocrystals)
    • Form: oral capsule (generic for Macrodantin)
    • Strengths: 25 mg, 50 mg, 100 mg
  • Brand: Macrobid
    • Form:Oral capsule
    • Strength:100 mg (75 mg nitrofurantoin monohydrate and 25 mg nitrofurantoin macrocrystals)
  • Brand: Macrodantin
    • Form: oral capsule
    • Strengths: 25 mg, 50 mg, 100 mg
  • Dosage for treatment of urinary tract infections
  • Adult dosage (ages 18–64 years): Macrodantin and its generic form: 50–100 mg four times per day.
  • Missed Dose:

  • As soon as you remember, take your dose. Take just one dose if you recall just a few hours before the next scheduled dose. Never try to make up for missed doses by taking two at once. This could have dangerous consequences.
  • Overdose:

  • It's possible that you have dangerously high levels of the opioid in your system. An overdose of this medication can cause the following symptoms: sleepiness, vomiting and tremor. If you think you have taken too much of this drug then consult with your doctor immediately.
  • Warnings for some serious health conditions :

  • Pregnancy:
  • If you're pregnant or planning to become pregnant, talk to your doctor. Animal experiments don't always predict how people will respond. In an infant, nitrofurantoin can cause red blood cell problems. As a result, pregnant women should avoid taking this medication:
  • When they are fully grown (38–42 weeks pregnant)
  • During labour and childbirth
  • If they assume they are in labour
  • Breastfeeding:
  • Nitrofurantoin can pass through breast milk and cause side effects in breastfed children. Consult your doctor about the possibility of breastfeeding your boy. It's likely that you'll have to choose between stopping breastfeeding and stop taking this drug.
  • Storage:

  • Direct contact with heat, air and light may damage your medicines. Exposure to medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach.
  • Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).
  • Nitrofurantoin vs Doxycycline:

    Nitrofurantoin
    Doxycycline
    Nitrofurantoin is an antibiotic used to treat infections of the urinary tract caused by several bacteria. E. coli, Enterobacter cystitis, Enterococcus, Klebsiella, and Staphylococcus aureus are all susceptible to it. Doxycycline is an antibiotic that fights the bacteria in the body. It is used to treat different bacterial infections like acne, urinary tract infections, intestinal infections, respiratory infections, eye infections and syphilis.
    This medicine is used to treat or avoid infections of the urinary tract. This drug is an antibiotic that works by preventing bacteria from growing. Doxycycline is used to treat acne by killing the bacteria which infect pores and also decrease the natural oily substance that causes acne.
    Some of the common side effects of Nitrofurantoin are: Some of the common side effects of Nitrofurantoin are:
    • Nausea
    • Vomiting
    • Loss of appetite
    • Stomach pain
    • Diarrhea
    Some of the common doxycycline side effects are: Some of the common side effects of Nitrofurantoin are:
    • Nausea
    • Vomiting
    • Diarrhea
    • Loss ofappetite
    • Itching of the rectum

    Frequently Asked Questions:

    Nitrofurantoin is an antibiotic used to treat infections of the urinary tract caused by a number of bacteria. E. coli, Enterobacter cystitis, Enterococcus, Klebsiella, and Staphylococcus aureus are all susceptible to it. Nitrofurantoin inhibits the synthesis of proteins, DNA, and cell walls in bacteria.
    Treatment usually lasts 3 to 7 days. Your UTI symptoms should start to fade away within the first 1 to 2 days of starting your antibiotics. It may take a few more days for you to notice an improvement if your UTI is more serious or if you've had symptoms for a long time before beginning antibiotics.
    Nitrofurantoin is a type of antibiotic used to treat urinary tract infections (UTIs) caused by bacteria including E. coli, Enterococcus, Klebsiella, Enterobacter cystitis, and Staphylococcus aureus. It prevents bacteria from developing proteins, DNA, and cell walls.
    Some of the common side effects of Nitrofurantoin are:
    • Nausea
    • Vomiting
    • Loss of appetite
    • Stomach pain
    • Diarrhea

    Citations:

  • Nitrofurantoin, https://journals.sagepub.com/doi/abs/10.1177/106002808501900706
  • Nitrofurantoin, https://academic.oup.com/jac/article-abstract/33/suppl_A/23/723385