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Nise

Nise

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By Medicover Hospitals / 11 Jan 2021
Home | Medicine | Nise

What is Nise ?

Nise 100 MG Tablet is a non-steroidal anti-inflammatory drug (NSAID) that is used as a second-line therapy to treat acute pain associated with osteoarthritis and menstruation. It is also used to treat mild to moderate pain due to sprains and strains of joints and muscles. This medicine is not recommended for use in patients below the age of 12 years.

Nise is used to treat back pains, arthritis, rheumatic arthritis, flank pains, thrombophlebitis, severe pains, and dysmenorrhea. Nise contains nimesulide as the main component and works by stopping the production of prostaglandin, which helps to relieve inflammation and pain

  1. Nise Uses
  2. Nise Side effects
  3. Nise Dosage
  4. Precautions
  5. Interactions
  6. Nise vs Paracetamol
  7. Frequently Asked Questions
  8. Citations

Use of the Nise 100 MG Tablet:

  • Acute pain
  • This medicine is used to relieve pain and swelling in the joints and muscles.
  • Dysmenorrhea Primary (Painful menstruation cycle)
  • This medicine is used to relieve acute menstrual pain.
  • Osteoarthritis Pain
  • This medicine is used to relieve symptomatic pain caused by osteoarthritis.
  • Migraines
  • Fever
  • Bursitis
  • Tendinitis
  • Sports Injuries
  • Stiffness in the joints

How do I use the Nise 100 MG Tablet?

  • Before taking The medicine, the patient should read the directions on the product label.
  • The patient should take Altraday Capsule as prescribed by the doctor and for the period specified by the doctor.
  • One should take the medicine twice or three times a day.
  • It is safe to use the Nise 100 MG Tablet for the period prescribed by the doctor.
  • Medicines should not be taken in more than the quantity prescribed, as an overdose may lead to problems with health, such as kidney disease or stomach bleeding.
  • Take Medication with a meal to prevent stomach upset.
  • Patients with kidney or liver disease should not take the medicine. It is recommended that the doctor be informed so that he/she can help with an appropriate alternative.
  • Do not drink alcohol after using the Nise 100 MG Tablet, as it may have an effect on the liver
  • In case of overdose, the doctor should be consulted immediately.
  • Take medicine with water without breaking, chewing, or crushing.

How does it work

  • It works by inhibiting cyclo-oxygenase (COX) enzymes that further inhibit prostaglandin production, which is the reason for pain initiation.
  • Prostaglandins at the site of injury are the cause of causing discomfort, swelling, and redness.
  • It helps to alleviate the discomfort and increases blood flow, heat loss, and sweating around the skin.
  • Nise 100 MG Tablet works by preventing the development of Cyclooxygenase, which in turn prevents prostaglandins from forming in the body. Inflammation and pain are responsible for both of these elements, namely, cyclooxygenase and prostaglandins.
  • The Nise 100 MG Tablet helps in improving the condition of a patient by blocking production of prostaglandin, thereby alleviating pain and inflammation caused by it. Nise 100 MG Tablet is also used for the treatment of Acute Pain and Dysmenorrhea.

Nise Side Effects:

  • Acidity
  • Nausea
  • Stomach cramps
  • Aches
  • Vomiting
  • Dizziness
  • Shortness of breath
  • Rashes
  • Hives
  • Tongue or face swelling

Severe side effects of Nise 100 MG Tablet might include some of the following:

  • Stevens-Johnson syndrome
  • Clotting of blood
  • Elevated enzyme levels in the liver
  • Skin rashes that are severe

Common Nise Dosage:

It is recommended to take Nise in the form of 100 mg tablets only. People with arthritis are advised not to take these tablets for a prolonged period of time. The dose of Nise 100 MG Tablet as prescribed by the physician after examining the patient's height, weight and medical history. Do not stop or start a new medicine without consulting your doctor. The Patient Shoe

Precautions:

The following precautions should be taken while taking the Nise 100 MG Tablet:

  • One should avoid taking the medicine with alcohol. You may experience side effects such as dizziness, rashes, sudden pain, etc.
  • If you are pregnant, it is recommended that you do not take these tablets for pain.
  • These tablets may cause bleeding in the gastrointestinal tract.
  • Side effects of the Nise 100 MG Tablet may be more severe among the elderly people due to lower immunity and resistance capacity.
  • Long periods of use of 100 mg Nise 100 MG Tablet may cause damage to the liver or kidneys.
  • If a person suffering from pain also has some heart conditions, he or she is advised not to take these tablets.
  • Breastfeeding mothers should take special care and avoid this tab.
  • Before consuming this medication, women who are pregnant or breastfeeding are advised to consult a doctor because it may be dangerous, especially during the last trimester. You are also recommended to avoid alcohol intake, too. You can experience symptoms such as nausea, extreme fatigue, joint pain, swelling, and fever if the Nise 100 MG Tab is taken with alcohol.

Interactions:

Nise 100 MG Tablet usually interacts with other drugs that may cause serious health problems. It is therefore advisable to discuss the current medicine and medical history with the doctor. Not all drugs that interact with Nise are included in this list. Patients should also not start, stop or change drugs without the doctor's approval.

  • Lithium
  • Methotrexate
  • Cyclosporine
  • Digitalis glycosides
  • Phenytoin

When not to use

Allergies

  • This medicine is not recommended for use in patients with known nimesulide allergy or any other inactive ingredients present in the formulation.

Liver Disease

  • This medicine is not recommended for use in patients with liver disease due to an increased risk of worsening of the condition of the patient.

Severe impairment of renal function

  • This medicine is not recommended for the use of patients who are having severe kidney impairment due to the increased risk of worsening of the patient's condition.

General instructions:

  • Take this medicine after a meal or as directed by your doctor. Do not take more than recommended/prescribed. Consult your doctor if you have any undesirable effects. Do not stop taking the medicine before the end of the course/without consulting your doctor.
  • To alleviate discomfort, inflammation, and fever, the Nise Tablet is used.
  • Take it with food or milk to reduce stomach pain.
  • Take it according to your doctor's prescribed dosage and length. Severe complications such as stomach bleeding and kidney problems may arise from long-term use of this medication.
  • If you are having a history of heart disease or stroke, tell your doctor.
  • When taking Nise Pill, avoid alcohol because it can raise the risk of stomach problems.
  • If you are planning to take this medication for long-term care, your doctor may check your kidney function, liver function, and levels of blood components regularly.

Overdose:

In the event of an overdose of Nise, the doctor should be contacted immediately, as gastric emptying (gastric lavage) should be done as a treatment measure. Overdose symptoms can be seen as drowsiness, lethargy, pain in the stomach, etc.

Missed dose:

If you skip a dose, the drug can not show sufficient effects because, for the drug to function efficiently, a certain amount of medicine must be present in the body at all times. As soon as you know, always take the missing dose. But, if it is already time to take a second dose after that, do not take a double dose, as this can lead to a drug overdose.

Nise vs Paracetamol:

Nise
Paracetamol
Nimesulide 100mg Known as acetaminophen
Used to treat acute pain, fever, flank pain Used to treat pain and fever
Painkiller Common painkiller
Formula: C13H12N2O5S Molar mass: 151.163 g/mol

Frequently Asked Questions:

Nise is used to treat acute back pain, arthritis, flank pain, thrombophlebitis, rheumatic arthritis, severe pain, and dysmenorrhea. Nise contains nimesulide as the main component and works by stopping the production of prostaglandin, which helps to relieve inflammation and pain.
This combination drug is used to relieve symptoms caused by the common cold, flu, asthma, or other respiratory disorders temporarily (such as sinusitis, bronchitis). Symptoms of a stuffy nose, sinus, and ear inflammation are relieved by decongestants. A non-aspirin pain reliever and fever reducer is acetaminophen (APAP).
Nimesulide exposes patients to liver damage that is fatal. It is safer to use one with a favorable benefit-harm balance, such as ibuprofen, when a non-steroidal anti-inflammatory drug is required.
Severe complications such as stomach bleeding and kidney problems can arise from long-term use of this drug. If you are having a history of heart disease or stroke, tell your doctor. When taking Nise Pill, avoid alcohol because it can raise the risk of stomach problems.

Citations:

  • Nise, https://www.jstor.org/stable/20485700?seq=1
  • Nise treatment https://rsp.ima-press.net/rsp/article/view/1305?locale=en_US