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Mitomycin

mitomycin

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By Medicover Hospitals / 01 March 2021
Home | Medicine | mitomycin

What is Mitomycin?

  • Mitomycin is a cancer drug that is used in conjunction with other medicines to treat cancers of the stomach and pancreas. Mitomycin treats only the symptoms of cancer of the stomach or pancreas, but cancer itself is not treated. As a single-agent, primary treatment, mitomycin is not recommended. In the treatment of disseminated stomach or pancreatic adenocarcinoma, it has been shown to be effective in proven combinations with other approved chemotherapeutic agents and as palliative therapy when other modalities have failed. It is not recommended to replace effective surgery and/or radiotherapy with mitomycin.
    1. Mitomycin Uses
    2. Mitomycin Side effects
    3. Precautions
    4. Dosage
    5. Pregnancy and Breastfeeding’s
    6. Storage
    7. Mitomycin vs Gemcitabine
    8. Frequently Asked Questions
    9. Citations

    Mitomycin Uses:

  • Mitomycin is a drug that is used in combination with other drugs to treat stomach or pancreatic cancer that has spread to other areas of the body and has not healed or deteriorated following treatment with other drugs, surgery, or radiation therapy. Mitomycin is a type of antibiotic that is used only for chemotherapy for cancer. It slows or prevents cancer cell growth in the body.
  • Mitomycin Side effects:

  • Some of the common side effects of Mitomycin are:
    • Nausea
    • Vomiting
    • Loss of appetite
    • Sores in the mouth
    • Headache
    • Fainting
    • Blurred vision
    • Hair loss
    • Loss of strength and energy
    • Rashes
  • Some of the serious side effects of Mitomycin are:
    • Pain
    • Itching
    • Redness
    • Swelling
    • Blisters
    • Shortness of breath
    • Difficulty breathing
    • Irregular heartbeat
  • Note that this drug has been prescribed by your doctor and he or she has decided that the value is greater than the risk of side effects. There are no significant side effects for many people who take this drug. Mitomycin can give your urine, tears, and sweat a reddish colour. This effect may begin within the first hours of treatment and may last for up to a few days. This is a natural drug reaction and should not be confused with blood in your urine.
  • Precautions:

  • Before using Mitomycin talk with your doctor if you are allergic to it or any other medications. The product may contain some inactive ingredients which can cause some serious allergic reactions or some other serious problems. Before taking Mitomycin talk with your doctor if you are having any medical history such as Bleeding disorders, severe infections, Kidney disease, Liver disease and any radiation treatment.
  • How to take Mitomycin?

  • Mitomycin comes in the form of powder which should be mixed with liquid and injected intravenously by the doctor. The medication is usually injected once every 6 to 8 weeks. MItramycin is an intravesical infusion that is used to treat superficial bladder cancer. It means if the medication is given directly in the bladder through the urinary catheter. The mitomycin solution is then injected into the catheter which is then removed. The medication is kept for about 2 hours after which the patient empties the bladder i.e. urinates.
  • Missed Dose

  • There will be no effect on your body if you skip one or two doses of Mitomycin. No issue is caused by a missed dose. But for some medicine, if you do not take the dose on time, it will not work. If you miss a dose, your body can experience a chemical change. In certain cases, if you miss a dose, the doctor will remind you to take the prescribed medication as soon as possible.
  • Overdose

  • Overdose of a drug can be accidental. If you have taken more than the prescribed Mitomycin tablets there is a chance of getting a harmful effect on your body’s functions. Overdose of a medicine can lead to some medical emergency.
  • Pregnancy and Breastfeeding’s

  • Mitomycin has not been proven to be effective in pregnant women. Animal experiments have revealed teratological changes. Mitomycin has no known effect on fertility.
  • Mitomycin passes into breast milk. It can cause some side effects to child’s who are breastfed. These can include diarrhea, vomiting and rash. Before taking Mitomycin while breastfeeding consult your doctor.
  • Storage

  • Direct contact with heat, air and light may damage your medicines. Exposure to medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach. Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).
  • Mitomycin vs Gemcitabine

    Mitomycin
    Gemcitabine
    Mitomycin is a cancer drug that is used in conjunction with other medicines to treat cancers of the stomach and pancreas. Gemcitabine belongs to the class of medications called antimetabolites. This works by slowing and stopping the growth of cancer cells in the body.
    Mitomycin is a type of antibiotic that is used only for chemotherapy for cancer. It slows or prevents cancer cell growth in the body. Gemcitabine is used for the treatment of certain types of cancer. This is a chemotherapy drug that works by slowing down the growth of cancer cells.
    Some of the common side effects of Mitomycin are:
  • Nausea
  • Vomiting
  • Loss of appetite
  • Sores in the mouth
  • Headache
  • Fainting
  • Some of the common side effects of Gemcitabine are:
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Loss of appetite
  • Headache
  • Frequently Asked Questions:

    Mitomycin is an anti-cancer chemotherapy medication ("antineoplastic" or "cytotoxic"). This medicine is known as an "antibiotic anti-tumour."
    Mitomycin C works by interfering with the growth of a cell's genetic material, DNA. This prevents and destroys it from breaking into 2 new cells. So, it kills cells that divide rapidly, such as cancer cells.
    A purple-coloured solution that can kill cells is mitomycin-C. When inserted into the bladder, it kills cancerous cells but does little harm to the normal, healthy bladder lining.
    Some of the common side effects of Mitomycin are:
    • -Nausea
    • -Vomiting
    • -Loss of appetite
    • -Sores in the mouth
    • -Headache
    • -Fainting
    Mitomycin, which can cause permanent kidney failure, may also destroy red blood cells. If you have unexplained bruises or bleeding, pale skin, confusion, tiredness, or irritability, stomach pain, bloody diarrhoea, red or pink urine, swelling, rapid weight gain, or little or no urinating, call the doctor right away.
    Mitomycin is a chemotherapy medication that is used to treat various cancers, including breast, bladder, stomach, pancreatic, anal, and lung cancers. This is details about mitomycin, which is injected into a vein.
    Mitomycin is a type of antibiotic that is used only for chemotherapy for cancer. It slows or prevents cancer cell growth in your body.

    Citations:

  • Mitomycin,https://www.sciencedirect.com/science/article/abs/pii/S0305737276800199
  • Mitomycin side effects,https://www.auajournals.org/doi/abs/10.1016/S0022-5347%2817%2954642-X