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What is Mitomycin?

Mitomycin is a cancer drug that is used in conjunction with other medicines to treat cancers of the stomach and pancreas. Mitomycin treats only the symptoms of cancer of the stomach or pancreas, but cancer itself is not treated. As a single-agent, primary treatment, mitomycin is not recommended. In the treatment of disseminated stomach or pancreatic adenocarcinoma, it has been shown to be effective in proven combinations with other approved chemotherapeutic agents and as palliative therapy when other modalities have failed. It is not recommended to replace effective surgery and/or radiotherapy with mitomycin.

Mitomycin Uses

Mitomycin is a drug that is used in combination with other drugs to treat stomach or pancreatic cancer that has spread to other areas of the body and has not healed or deteriorated following treatment with other drugs, surgery, or radiation therapy. Mitomycin is a type of antibiotic that is used only for chemotherapy for cancer. It slows or prevents cancer cell growth in the body.

Mitomycin Side effects

Some of the common side effects of Mitomycin are:

  • Nausea
  • Vomiting
  • Loss of appetite
  • Sores in the mouth
  • Headache
  • Fainting
  • Blurred vision
  • Hair loss
  • Loss of strength and energy
  • Rashes

Some of the serious side effects of Mitomycin are:

  • Pain
  • Itching
  • Redness
  • Swelling
  • Blisters
  • Shortness of breath
  • Difficulty breathing
  • Irregular heartbeat

Note that this drug has been prescribed by your doctor and he or she has decided that the value is greater than the risk of side effects. There are no significant side effects for many people who take this drug. Mitomycin can give your urine, tears, and sweat a reddish colour. This effect may begin within the first hours of treatment and may last for up to a few days. This is a natural drug reaction and should not be confused with blood in your urine.

Precautions

Before using Mitomycin talk with your doctor if you are allergic to it or any other medications. The product may contain some inactive ingredients which can cause some serious allergic reactions or some other serious problems. Before taking Mitomycin talk with your doctor if you are having any medical history such as Bleeding disorders, severe infections, Kidney disease, Liver disease and any radiation treatment.

How to take Mitomycin?

Mitomycin comes in the form of powder which should be mixed with liquid and injected intravenously by the doctor. The medication is usually injected once every 6 to 8 weeks. MItramycin is an intravesical infusion that is used to treat superficial bladder cancer. It means if the medication is given directly in the bladder through the urinary catheter. The mitomycin solution is then injected into the catheter which is then removed. The medication is kept for about 2 hours after which the patient empties the bladder i.e. urinates.

Missed Dose

There will be no effect on your body if you skip one or two doses of Mitomycin. No issue is caused by a missed dose. But for some medicine, if you do not take the dose on time, it will not work. If you miss a dose, your body can experience a chemical change. In certain cases, if you miss a dose, the doctor will remind you to take the prescribed medication as soon as possible.

Overdose

Overdose of a drug can be accidental. If you have taken more than the prescribed Mitomycin tablets there is a chance of getting a harmful effect on your body’s functions. Overdose of a medicine can lead to some medical emergency.

Pregnancy and Breastfeeding’s

Mitomycin has not been proven to be effective in pregnant women. Animal experiments have revealed teratological changes. Mitomycin has no known effect on fertility.

Mitomycin passes into breast milk. It can cause some side effects to child’s who are breastfed. These can include diarrhea, vomiting and rash. Before taking Mitomycin while breastfeeding consult your doctor.

Storage

Direct contact with heat, air and light may damage your medicines. Exposure to medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach. Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).

Fondaparinux vs Heparin:

Mitomycin

Gemcitabine
Mitomycin is a cancer drug that is used in conjunction with other medicines to treat cancers of the stomach and pancreas. Gemcitabine belongs to the class of medications called antimetabolites. This works by slowing and stopping the growth of cancer cells in the body.
Mitomycin is a type of antibiotic that is used only for chemotherapy for cancer. It slows or prevents cancer cell growth in the body. Gemcitabine is used for the treatment of certain types of cancer. This is a chemotherapy drug that works by slowing down the growth of cancer cells.
Some of the common side effects of Mitomycin are:
  • Nausea
  • Vomiting
  • Loss of appetite
  • Sores in the mouth
  • Headache
  • Fainting
 Some of the common side effects of Gemcitabine are:
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Loss of appetite
  • Headache

Citations

Mitomycin C: a review
Side Effects Associated with Intravesical Mitomycin C

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Frequently Asked Questions

What type of drug is mitomycin?

Mitomycin is an anti-cancer chemotherapy medication ("antineoplastic" or "cytotoxic"). This medicine is known as an "antibiotic anti-tumour."

How does mitomycin C work?

Mitomycin C works by interfering with the growth of a cell's genetic material, DNA. This prevents and destroys it from breaking into 2 new cells. So, it kills cells that divide rapidly, such as cancer cells.

How does mitomycin work for bladder cancer?

A purple-coloured solution that can kill cells is mitomycin-C. When inserted into the bladder, it kills cancerous cells but does little harm to the normal, healthy bladder lining.

What are the side effects of mitomycin C?

Some of the common side effects of Mitomycin are:

  • Nausea
  • Vomiting
  • Loss of appetite
  • Sores in the mouth
  • Headache
  • Fainting

Does mitomycin cause weight gain?

Mitomycin, which can cause permanent kidney failure, may also destroy red blood cells. If you have unexplained bruises or bleeding, pale skin, confusion, tiredness, or irritability, stomach pain, bloody diarrhoea, red or pink urine, swelling, rapid weight gain, or little or no urinating, call the doctor right away.

Is mitomycin chemotherapy?

Mitomycin is a chemotherapy medication that is used to treat various cancers, including breast, bladder, stomach, pancreatic, anal, and lung cancers. This is details about mitomycin, which is injected into a vein.

Is mitomycin an antibiotic?

Mitomycin is a type of antibiotic that is used only for chemotherapy for cancer. It slows or prevents cancer cell growth in your body.

Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.