Mebeverine is an antispasmodic medicine, such as mebeverine hydrochloride, commonly used to relieve abdominal pain and cramps caused by digestive disorders like IBS. It works by relaxing the muscles in the intestinal wall, easing discomfort and improving bowel movement regularity.

  • This is an anticholinergic drug.
  • Mebeverine is available in the form of tablets or slow-release capsules (also called modified release).
  • Colofac, Colofac IBS, and Aurobeverine are all brand names for mebeverine.
  • If you have Irritable bowel syndrome, you can take mebeverine mixed with ispaghula husk (brand name Fybogel Mebeverine) to relieve constipation.

What Are the Uses of Mebeverine Tablets?

Mebeverine hydrochloride is used to treat painful digestive issues caused by bowel spasms and inflammatory conditions.

Conditions Mebeverine Helps Treat

Secondary Uses of Mebeverine

  • Helps relieve constipation when used with ispaghula husk
  • May be prescribed in other cases of bowel irritation or inflammation

How Does Mebeverine Work (Mechanism of Action)?

Mebeverine acts directly on the muscles of the intestinal wall to reduce spasms and cramping.

By relaxing the smooth muscles of the gut, it prevents painful contractions without affecting normal bowel movements. As an anticholinergic agent, it blocks certain nerve signals that cause intestinal spasms.

Dosage Instructions for Mebeverine

Mebeverine is available in various dosage forms to suit different patient needs, including tablets, capsules, and oral suspension for easier administration.

Form Strengths Available Usage
Mebeverine Tablets (Immediate Release) 135 mg Taken 2 to 3 times daily before meals
Mebeverine Capsules (Slow Release) 200 mg Usually taken twice a day (morning and evening)
Mebeverine Suspension (in some regions) Varies by brand Used in patients who have difficulty swallowing

Always use this medication exactly as directed by your doctor. Do not change the dosage without consulting your healthcare provider.

How to take Mebeverine?

  • Take Mebeverine tablet about 20 minutes before meals, as this helps prevent spasms triggered by eating.
  • Do not crush or chew the tablets or capsules. Swallow them whole with a glass of water.
  • This drug is believed to have an anaesthetic effect by directly acting on the smooth muscles of the gastrointestinal tract.
  • It's prescribed for irritable bowel syndrome, and the dosage varies depending on the form of the medication-pills, capsules, or liquid.

What Should I Do If I Miss a Dose?

  • It is necessary to take the missed dose as soon as possible.
  • If your next scheduled dose is approaching, it is better to skip the skipped dose.
  • To make up for a missed dose, do not take extra medication.

What happens if an Overdose?

  • Overdosing on Mebeverine can be harmful and requires the patient should consult a doctor immediately.

Common overdose symptoms may include:

  • Dizziness
  • Confusion
  • Restlessness

In severe cases, gastric lavage (stomach wash) may be needed.

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What are the Side Effects of Mebeverine?

Side effects are usually mild but can vary between individuals. Always monitor how your body reacts and consult a doctor if symptoms persist.

Common Side Effects

Serious but Rare Side Effects

If you have any of these serious symptoms, see your doctor right away. If you encounter any side effects from Mebeverine, try to prevent them.

Precautions Before Taking Mebeverine

Before taking Mebeverine tablet, talk to your doctor if you are allergic to it or any other medications and any medical history like:

Who should avoid this medicine?

Pregnancy

Pregnant women should not take this medicine unless it is absolutely required. Before taking this drug, speak to your doctor about all of the complications and benefits.

Breastfeeding

  • This drug should be avoided by women who are breastfeeding, unless absolutely necessary.
  • Consult your doctor before taking this medication to understand all potential risks and benefits.

Kidney Disease

  • This drug should be used with caution in patients with kidney disease.
  • There is an increased risk of serious side effects in such cases.
  • Depending on the patient's condition, kidney function may need to be closely monitored.
  • Dosage adjustments or an alternative medication may be required for safe treatment.

Acute Porphyria

  • This drug is not approved for use in patients with acute porphyria.
  • Using it may worsen the patient's condition.
  • Depending on the patient's health, a suitable alternative medication'should be considered.

Are There Any Age Restrictions for Using Mebeverine?

  • The drug should only be used if prescribed to children below the age of 10 or if absolutely necessary.
  • Only children over the age of ten may be given this medicine.

Possible Interactions with Other Medications

Drug interactions can affect how Mebeverine works or increase the risk of side effects.

  • Always let your doctor know about any medications or supplements you are currently taking.
  • Use caution when combining it with other anticholinergic or gastrointestinal drugs.

No major interactions are common, but it's important to follow professional advice for safe usage.

How Should Mebeverine Be Stored?

Proper storage ensures the effectiveness and safety of the medicine.

  • Mainly, the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).
  • Direct contact with heat, air, and light may damage your medicines.
  • The exposure of medicine may cause some harmful effects.
  • The medicine must be kept in a safe place and out of children's reach.

Improper storage can degrade the medication, reducing its effectiveness or causing harm.

Mebeverine vs Dicyclomine

Mebeverine Dicyclomine
Mebeverine is available in the form of tablets or slow-release capsules (also called modified release). If you have trouble swallowing tablets, it is sometimes available as a liquid. Dicyclomine oral tablet is a prescription medicine. It's available as a brand-name Bentyl drug.
Mebeverine is used for the treatment of various symptoms of digestive disorders and irritable bowel conditions, such as spastic colitis, spastic constipation, colon inflammation, and mucous colitis. Dicyclomine is used to treat symptoms such as stomach spasms caused by intestinal disorders, including irritable bowel syndrome.
Some of the common and serious side effects of Mebeverine are:
  • Nausea
  • Vomiting
  • Rash
  • Headache
Some of the common and serious side effects of Dicyclomine are:
  • Dry mouth
  • Dizziness
  • Nausea
  • Hives

References

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Frequently Asked Questions

No, Mebeverine and Buscopan are not the same medications, although they are both used to treat gastrointestinal disorders like irritable bowel syndrome. They have different active ingredients and mechanisms of action.

Mebeverine is not typically used to treat diarrhea. It's mainly prescribed for relieving symptoms associated with irritable bowel syndrome (IBS).

It's well-tolerated and hasn't produced any severe side effects. Mebeverine 200 mg is as effective as mebeverine 135 mg in clinical improvement and relief of abdominal pain, according to the meta-analysis. Mebeverine 200 mg had no major side effects, according to the findings.

Mebeverine should be taken 20 minutes before a meal. It functions by relaxing complex gut muscles. After an hour, Mebeverine begins to work. Mebeverine is usually healthy, and side effects are rare.

The recommended dosage of Mebeverine 135mg is usually one tablet taken three times a day, preferably 20 minutes before meals. However, the dosage may vary based on the doctor's prescription.

Mebeverine is generally not recommended during pregnancy unless prescribed by a doctor. Always consult your healthcare provider first.

Mebeverine usually starts relieving symptoms within 1 to 3 hours, but it may take a few days of regular use to feel full benefits.

Yes, Mebeverine can help relieve bloating and abdominal discomfort caused by irritable bowel syndrome (IBS) and other gut spasms.

No, store Mebeverine at room temperature away from moisture and heat. Refrigeration is not required.

Mebeverine relaxes gut muscles slowly and is used long-term, while Buscopan works faster and is often used for sudden cramps or spasms.


Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.

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