The Le Cell test detects the presence of lupus erythematosus cells in your blood, which can indicate the presence of systemic lupus erythematosus (SLE). This simple blood test is used to diagnose autoimmune disorders. It carries minimal risks, such as mild pain or bruising at the sample site. The cost may vary based on location, and the results help doctors diagnose and manage lupus-related conditions.
What is the LE Cell Test?
The lupus erythematosus (LE) cell test is (Systemic lupus erythematosus) SLE diagnostic test. SLE is a chronic autoimmune illness that causes the immune system to attack healthy cells.
The test outcome is affected by subjective interpretation and experimental factors. Antinuclear antibody (ANA) testing is more accurate than the LE cell test.
What is the use of the LE Cells Test?
The LE cell test is used to identify SLE, an autoimmune illness. The test is used on both men and women. The test is advised when SLE symptoms are present, which include extreme tiredness, joint inflammation, joint pain, and butterfly rashes on the nose and cheeks.
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Get Second OpinionWhat is the need for an LE Cells Test?
The LE cell phenomenon test? is typically used to diagnose autoimmune diseases, SLE, and chronic active hepatitis. It is advised when symptoms such as weariness, joint inflammation, or joint discomfort are present.
What happens during the LE Cells Test?
During the le cells blood test?, the blood sample is taken and then it is tested in the lab where the blood cells from the patient are ruptured, which leads to the release of nuclear material. Phagocytosis occurs when nuclear material is liberated and interacts with certain antibodies.
How to Interpret the LE Cells Test Results
A skilled healthcare practitioner should evaluate the findings of the LE cell test, and people should avoid self-diagnosis. A negative test is a normal range. If LE cells account for around 2-30% of the neutrophil cells in the smear, the test is termed positive.
A positive LE cell test can also be seen in patients with chronic hepatitis, rheumatoid arthritis, dermatomyositis, scleroderma, polyarteritis nodosa, acquired hemolytic anemia, Hodgkin's disease, and those using hydralazine or phenylbutazone.
Advantages and Limitations of the LE Cell Test
Advantages:
- Useful in diagnosing autoimmune conditions in the past
- LE cell test procedure
- LE Cell Test Method.
Limitations:
- Subjective interpretation of results.
- Experimental factors can affect outcomes.
- Modern tests like the ANA test provide more reliable and accurate results.
Why is the LE Cell Test Done?
The LE Cell Test is mainly done to help diagnose systemic lupus erythematosus (SLE) and differentiate it from other autoimmune disorders. It helps doctors confirm the presence of abnormal immune system activity.
When is the LE Cell Test Needed?
Doctors may recommend the LE Cell Test if you experience:
- Persistent joint pain or swelling
- Skin rashes, especially a butterfly-shaped rash on the face
- Chronic fatigue
- Unexplained fever
- Chest pain during breathing
- Kidney problems without an obvious cause
Who Should Take the LE Cell Test?
- Individuals showing signs of autoimmune disease
- Patients with a family history of lupus
- People with unexplained inflammatory symptoms
- Women, as they are more commonly affected by lupus
- Individuals with abnormal findings on other blood tests (like ANA test)
How Should I Prepare for the LE Cell Test?
No special preparation is needed for the LE Cell Test. You can eat and drink as usual unless otherwise instructed by your doctor.
What Type of Sample is Collected for the LE Cell Test and How?
A blood sample is collected using a small needle inserted into a vein, typically from the arm.
Are There Other Ways to Collect the Sample for the LE Cell Test?
No, the LE Cell Test requires a blood sample from a vein. There are no alternate collection methods.
How is the LE Cell Test Performed?
- Your arm will be cleaned with antiseptic.
- A healthcare provider will insert a needle into your vein to draw blood.
- The sample is collected into a sterile tube.
- The blood is then sent to the lab, where it is specially prepared and examined under a microscope for LE cells.
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How Long Does the LE Cell Test Take?
The blood collection takes only a few minutes. The lab analysis may take a few hours to complete.
When Will I Get My LE Cell Test Results?
You will usually receive your LE Cell Test results within 12 to 24 hours, depending on the lab's processing time. Reports are sent directly to you via WhatsApp or as a printed copy. Once you have your results, our doctor will explain them and guide you on the next steps, if needed.
How Do I Understand My LE Cell Test Results?
- Negative Result: No LE cells found; lupus is less likely.
- Positive Result: LE cells found; indicates the possibility of lupus or a related autoimmune disorder. Further tests may be needed for confirmation.
What Should I Do After Getting My LE Cell Test Results?
If the result is positive, your doctor may recommend additional tests like ANA (Antinuclear Antibody) or anti-dsDNA tests to confirm the diagnosis and start appropriate treatment.
Are There Any Risks or Side Effects of the LE Cell Test?
The LE Cell Test is very safe. Minor risks include slight pain, bruising, or faintness at the site of blood draw, but these are rare and temporary.
Is the LE Cell Test Painful?
The test causes only minimal discomfort, similar to a small pinch when the needle is inserted.
What are the Factors Affecting LE Cell Test Cost?
- Type of lab (basic or specialized diagnostic center)
- City or geographical location
- Whether the test is done alone or as part of a lupus screening panel
- Home collection charges
- Consultation fees for reviewing results
How Much Does the LE Cell Test Cost in India?
The average cost of an LE Cell Test in India is around Rs.400 to Rs.1,200. However, the price can change depending on the hospital and the city.
LE Cell Test Price in Different Cities Across India:
| City | Price |
| Hyderabad | Rs.400 to Rs.1,200 |
| Karimnagar | Rs.400 to Rs.1,200 |
| Nizamabad | Rs.400 to Rs.1,200 |
| Warangal | Rs.400 to Rs.1,200 |
| Vizag | Rs.400 to Rs.1,200 |
| Srikakulam | Rs.400 to Rs.1,200 |
| Kakinada | Rs.400 to Rs.1,200 |
| Kurnool | Rs.400 to Rs.1,200 |
| Nellore | Rs.400 to Rs.1,200 |
| Vizianagaram | Rs.400 to Rs.1,200 |
| Navi Mumbai | Rs.400 to Rs.1,200 |
| Nashik | Rs.400 to Rs.1,200 |
| Chh. Sambhaji nagar | Rs.400 to Rs.1,200 |
| Pune | Rs.400 to Rs.1,200 |
| Sangamner | Rs.400 to Rs.1,200 |
| Bangalore | Rs.400 to Rs.1,200 |
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Frequently Asked Questions
The LE cell test is a test that detects a type of cell called a "LE cell" in a blood sample. LE cells are white blood cells that have engulfed and digested another type of cell called a "neutrophil." LE cells in the blood can indicate that the body's immune system is attacking its own tissues, which is a hallmark of SLE.
A small amount of blood is drawn from a vein in the arm and sent to a laboratory for analysis.
A positive LE cell test result means LE cells were found in the blood sample. This can be an indication of SLE, but it is not a definitive diagnosis. Other tests and clinical evaluations are needed to confirm a diagnosis of SLE.
The LE cell test is not always reliable for diagnosing SLE. It may be negative in some people with SLE, and it may be positive in people without SLE. Therefore, other tests and clinical evaluations are needed to confirm a diagnosis of SLE. Additionally, the test is not commonly used anymore and has been replaced by more specific and sensitive tests.
The LE cell test is a relatively simple blood test and is considered safe. However, like any blood test, there is a small risk of bleeding, infection, or bruising at the site where the needle was inserted. These risks are very low and are generally outweighed by the benefits of the test in diagnosing or monitoring SLE.
The LE cell test was commonly used in the past, but it is not used any more due to its limited sensitivity and specificity. Instead, other tests, such as the ANA test and anti-dsDNA antibody test, are typically used to diagnose SLE.
Yes, it is possible for a person with SLE to have a negative LE cell test result. This is because the LE cell test is not the standard for diagnosing SLE, and it may be negative in some people with the disease.
Yes, certain medications can affect the results of the LE cell test. For example, some medications used to treat autoimmune diseases can cause LE cells to form, even in people who do not have SLE. Therefore, it is important to tell your doctor about any medications you are taking before having the LE cell test or any other blood tests.
LE cell test costs around Rs. 400 approximately. However, the cost can differ from place to place.
You can get an LE cell test at Medicover Hospitals.
