LE Cell Test
What is the LE Cell Test?
The lupus erythematosus (LE) cell test is (Systemic lupus erythematosus) SLE diagnostic test. SLE is a chronic autoimmune illness that causes the immune system to attack healthy cells.
The test outcome is affected by subjective interpretation and experimental factors. Antinuclear antibody (ANA) testing is more accurate than the LE cell test.
What is the use of the LE Cells Test?
The LE cell test is used to identify SLE, an autoimmune illness. The test is used on both men and women. The test is advised when SLE symptoms are present, which include extreme tiredness, joint inflammation,joint pain, and butterfly rashes on the nose and cheeks.
What is the need for an LE Cells Test?
LE cell tests are typically used to diagnose autoimmune diseases, SLE, and chronic active hepatitis. It is advised when symptoms such as weariness, joint inflammation, or joint discomfort are present.
What happens during the LE Cells Test?
During the LE cell test, the blood sample is taken and then it is tested in the lab where the blood cells from the patient are ruptured, which leads to the release of nuclear material. Phagocytosis occurs when nuclear material is liberated and interacts with certain antibodies.
How to Interpret the LE Cells Test Results
A skilled healthcare practitioner should evaluate the findings of the LE cell test, and people should avoid self-diagnosis. A negative test is a normal range. If LE cells account for around 2-30% of the neutrophil cells in the smear, the test is termed positive.
A positive LE cell test can also be seen in patients with chronic hepatitis,rheumatoid arthritis, dermatomyositis,scleroderma, polyarteritis nodosa, acquired hemolytic anemia, Hodgkin's disease, and those using hydralazine or phenylbutazone.