Ursodiol is a bile acid medication used to reduce the amount of cholesterol produced by the liver and absorbed by the intestines. It helps dissolve cholesterol-based gallstones and promotes healthy bile flow, particularly in people with early-stage primary biliary cirrhosis (PBC). It is commonly prescribed when surgery for gallstones is not an option or to support liver health in certain chronic conditions.

What are the Uses of Ursodiol 300 mg Tablet?

Ursodiol tablet is primarily used to dissolve certain types of gallstones and treat primary biliary cholangitis. It helps improve liver function by reducing the buildup of bile acids. This medication'supports smoother digestion and liver health in individuals affected by these conditions.

  • Gallstone Dissolution: Helps dissolve small cholesterol gallstones in patients who cannot undergo surgery.
  • Gallstone Prevention in Rapid Weight Loss: This prevents gallstone formation in obese individuals from rapidly losing weight, which is a common side effect of drastic weight reduction.
  • Primary Biliary Cirrhosis (PBC): Improves liver function in patients with early-stage PBC by reducing toxic bile acids and improving bile flow.

How Does Ursodiol Work?

Ursodiol works by

  • Reducing liver cholesterol production
  • Decreasing cholesterol absorption from the intestine
  • Helping to dissolve existing cholesterol gallstones
  • Improving bile flow and reducing bile toxicity in liver diseases

Dosage: How to Take Ursodiol

Ursodiol dosage varies depending on the condition being treated and the individual patient's needs. It is typically taken with food to enhance absorption and minimize stomach upset. Consistent timing and adherence to your doctor's instructions are crucial for achieving the best results.

Recommended Dosage

  • Gallstone Dissolution: Usually taken 2 to 3 times daily, with or without food.
  • Gallstone Prevention (Weight Loss): Twice a day, often recommended during periods of rapid weight loss.
  • Primary Biliary Cirrhosis: Typically 2 to 4 times daily with food, depending on body weight and condition severity.

Important Tips

  • Swallow tablets or capsules whole with water.
  • Take it at the exact times each day to maintain consistent levels in the body.
  • Do not stop taking it without your doctor's advice, even if symptoms improve.

Missed Dose

If you miss a dose:

  • Take it as soon as you remember.
  • Skip it if it's almost time for your next dose.
  • Do not take two doses to make up for the missed one.

Overdose

Overdosing on Ursodiol may lead to side effects like diarrhea or liver-related complications. In case of suspected overdose:

  • Seek immediate medical attention
  • Contact your local poison control center or emergency services

Get a second opinion from trusted experts and makeconfident, informed decisions.

Get Second Opinion

What are the Side Effects of Ursodiol Tablet?

While many people tolerate Ursodiol well, some may experience mild side effects like diarrhea or stomach pain. Rare but serious side effects should be reported to a healthcare provider. Monitoring your response can help manage and minimize any discomfort.

Common Side Effects

  • Diarrhea or constipation
  • Nausea, vomiting, or indigestion
  • Dizziness or headache
  • Fever, cough, or sore throat
  • Back pain or muscle/joint pain
  • Hair loss

Serious Side Effects (Rare)

  • Severe allergic reactions:
    • Rash
    • Itching/swelling
    • Breathing difficulty

If you experience any severe reactions, stop taking the medication and consult your doctor immediately.

Precautions Before Using Ursodiol

Certain liver or gallbladder conditions may require extra caution when using Ursodiol. Discuss your complete medical history and any allergies with your doctor before starting treatment. Regular liver function tests may be needed during long-term use.

  • Liver disease
  • Ascites (fluid in the abdomen)
  • Variceal bleeding (esophageal veins)
  • Hepatic encephalopathy (mental confusion due to liver failure)
  • Allergies to bile acids or other ingredients in the medication

Drug Interactions

Ursodiol may interact with medications like cholesterol-lowering agents, antacids, or oral contraceptives. Such interactions could affect how Ursodiol or the other drugs work. Be sure to provide your doctor with a complete list of your medications and supplements.

  • Aluminum-containing antacids
  • Estrogen-based medications or birth control pills
  • Cholesterol-lowering medications (like cholestyramine or colestipol)

To avoid interactions, take Ursodiol and other medications at least 1-2 hours apart.

Ursodiol Udiliv
Reduces cholesterol produced by the liver and absorbed by the intestines. Dissolves cholesterol gallbladder stones and treats liver-related disorders such as cirrhosis and sclerosing cholangitis.
Used to dissolve gallstones and treat primary biliary cirrhosis. Used for dissolving gallstones in people who do not want surgery.
Common Side Effects: Diarrhea, constipation, nausea, indigestion, dizziness, headache. Common Side Effects: Abdominal pain, diarrhea, hair loss, itching, nausea, rash.

References

Ursodiol for Hepatobiliary Disorders
Ursodiol
Book Doctor Appointment
Book Free Appointment

Still have questions? Speak with our experts now!

040-68334455

Frequently Asked Questions

Ursodiol medicine is used for the treatment of people with primary biliary cirrhosis. It belongs to the class of medications called gallstone dissolution agents.

Ursodiol is used to dissolve and prevent cholesterol gallstones. The medication blocks the enzyme in the liver that produces cholesterol, thereby decreasing the production of cholesterol.

Ursodiol is commonly prescribed to treat gallstones. It helps remove cholesterol that has formed into gallbladder stones and improves patient bile flow.

During the treatment with Ursodiol for the dissolution of gallstones, the symptoms of biliary distress begin to improve after 3 to 6 weeks.

If you stop taking Ursodiol, the gallstones may not dissolve. The type of diet the patient follows can affect the stones’ ability to dissolve.

Ursodiol should be stored at room temperature, away from moisture and direct sunlight. Keep it in its original container with the lid tightly closed. Make sure it’s stored in a dry place and out of reach of children and pets.

The recommended storage temperature for Ursodiol is between 20°C to 25°C (68°F to 77°F). Temporary temperature variations between 15°C and 30°C (59°F to 86°F) are generally acceptable.

Improper storage of Ursodiol can reduce its effectiveness and may even cause the medication to degrade. Exposure to excessive heat, light, or moisture may alter the chemical composition, potentially leading to reduced therapeutic benefits or unexpected side effects.


Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.

Book Appointment Second Opinion WhatsApp Health Packages Find Doctors

Feeling unwell?

Request a callback!