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Prostin

prostin

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By Medicover Hospitals / 09 Mar 2021
Home | Medicine | prostin

What is Prostin?

  • Prostin is a prostaglandin E2 that occurs naturally (PGE2). The medications have important effects on labour. Prostin stimulates osteoblasts by releasing factors that stimulate bone resorptions by osteoclasts. It is used as a vaginal suppository, to prepare the cervix for labour, and to induce labour as a prescription medication. Prostin is a prostaglandin, which is a hormone-like substance released by the body's tissues. In a pregnant woman, prostin E2 is used to relax the muscles of the cervix (uterus opening) in preparation for inducing labour at the end of the pregnancy.
    1. Prostin Uses
    2. Prostin Side effects
    3. Precautions
    4. Overdose
    5. Warnings
    6. Storage
    7. Prostin vs Cytotec
    8. Frequently Asked Questions
    9. Citations

    Prostin Uses:

  • Prostin is used to cause abortion during 12-20 weeks of pregnancy. It's also used to help vaginally extract any residual substance in the womb after a miscarriage or failed abortion up to 28 weeks of pregnancy. The womb contracts and pushes out its contents, including the placenta and the fetus/unborn infant. Prostin is a natural substance (prostaglandin) produced by your body is in anticipation of labour. It softens and widens the opening of the womb while increasing contractions. It's also used to treat a specific type of womb condition (benign hydatiform mole). This drug should not be used for cervical ripening or any other purpose in a pregnancy nearing the end.
  • Prostin Side Effects:

  • Some of the side effects of Prostin are:
    • Fever
    • Irregular heartbeats
    • Nausea
    • Stomach pain
    • Back pain
    • Fever
  • Some of the serious side effects of Prostin are:
    • Light-headed feeling
    • Weak or shallowing breathing
    • Vaginal bleeding
    • Unexpected stomach pain
    • Chest pain
    • Easy bruising
    • Bleeding from wound
  • Prostin can cause some serious side effects. Avoid using the medicine if you feel any adverse effects and contact your doctor immediately. The doctor might change the prescribed dose or medicine looking at your side effects.
  • Precautions:

  • Before using Prostin talk with your doctor if you are allergic to it or any other medications. The product may contain some inactive ingredients which can cause some serious allergic reactions or some other problems. Before using Prostin talk with your doctor if you are having any medical history such as Anemia, asthma, low blood pressure, diabetes, glaucoma, heart disease, kidney disease, liver disease, infections in the vaginal area and seizure disorder.
  • How to take Prostin?

  • A health care provider inserts the suppository high in the vagina, and you must stay in a reclined or lying-down position for at least 10 minutes after insertion. Additional doses can be given every 3-5 hours before the desired effect is achieved. Usage for no more than 48 hours. This medicine can only be used in a hospital environment under the supervision of a qualified medical professional. Changes in your womb can be tracked (water breaking, strong/long-lasting contractions, etc.). Other care (such as surgical removal) may be required if the desired outcome has not occurred in 48 hours or if the abortion is incomplete. This drug can be combined with oxytocin, a vein-based medication, to help improve contractions. To avoid serious, rarely fatal complications such as extreme infection and bleeding, all pregnancy products (such as fetal/unborn baby tissue, placenta) must be removed.
  • Missed Dose:

  • If you skip a dose of this drug, take it as soon as you recall. If it's almost time for your next dose, skip the skipped one and go straight to the next. To make up for a missed dose, do not double the dose.
  • Overdose:

  • Overdose of a drug can be accidental. If you have taken more than the prescribed Prostin tablets there is a chance of getting a harmful effect on your body’s functions. Overdose of a medicine can lead to some medical emergency.
  • Warnings for some Serious Health Conditions:

  • Pregnancy: Prostin E2 (dinoprostone) Vaginal Suppository is a hormone-like substance (prostaglandin) produced by the body in preparation for labour that is used in pregnant women to relax the muscles of the cervix (uterus opening) in preparation for inducing labour at the end of the pregnancy.
  • Breastfeeding: If you plan to breastfeed your infant, tell your doctor, nurse, or other healthcare providers. Prostin 15M is not believed to be excreted in human breast milk. Before breastfeeding your infant, you must wait at least 6 hours after your last Prostin 15M dose. This medication should not be given to infants.
  • Storage:

  • Direct contact with heat, air and light may damage your medicines. Exposure to medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach. Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).
  • Prostin vs Cytotec:

    Prostin
    Cytotec
    Prostin is a prostaglandin E2 that occurs naturally (PGE2). The medication has important effects on labour. Cytotec protects the stomach from the damage caused by nonsteroidal anti-inflammatory drugs such as aspirin, ibuprofen, naproxen, celecoxib, diclofenac, indomethacin, meloxicam, and others.
    Prostin is a natural substance (prostaglandin) produced by your body is in anticipation of labour. It softens and widens the opening of the womb while increasing contractions. This medicine is used to prevent stomach ulcers when taking nonsteroidal anti-inflammatory drugs (e.g., aspirin, ibuprofen, naproxen), especially if you are at risk for ulcers or have a history of ulcers
    Some of the side effects of Prostin are:
    • Fever
    • Irregular heartbeats
    • Nausea
    • Stomach pain
    • Back pain
    Some of the common side effects of Cytotec are:
    • Diarrhea
    • Stomach pain
    • Nausea
    • Vaginal bleeding

    Frequently Asked Questions:

    If no contractions have occurred after 6 hours, you will be given another tablet or gel. It can take up to 24 hours for a controlled-release pessary inserted into your vagina to start working. You could be given another dose if you do not have contractions after 24 hours.
    This gel is injected into the cervix by a syringe inserted into the vaginal canal. The medication aids in the dilation of the cervix, allowing the birth canal to develop. The contractions should start slowly, and you will be able to return home after the gel has been applied for a few hours.
    Prostaglandins are extremely safe to use. Serious side effects of the medications used are extremely uncommon. Some women experience intense “prostin” contractions, which can lead to diarrhoea. Some women may experience a prolonged contraction, which may affect the baby's heart rate.
    Some of the side effects of Prostin are:
    • Fever
    • Irregular heartbeats
    • Nausea
    • Stomach pain
    • Back pain
    Side effects Prostin is a natural substance (prostaglandin) produced by your body is in anticipation of labour. It softens and widens the opening of the womb while increasing contractions.

    Citations:

  • Prostin, https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-2007-999875
  • Prostin https://www.tandfonline.com/doi/abs/10.1080/01443610600903362