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Prasugrel

Prasugrel

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By Medicover Hospitals / 03 March 2021
Home | Medicine | Prasugrel
  • Prasugrel is an antiplatelet drug that prevents platelets in the bloodstream from aggregating and forming blood clots. It is used to avoid blood clots in patients with an acute coronary syndrome that are having surgery following a recent heart attack or stroke, as well as in people with some heart or blood vessel disorders. Prasugrel is sold under brand names, Efficacious.
    1. Prasugrel Uses
    2. Prasugrel Side Effects
    3. Precautions
    4. Dosage
    5. Prasugrel vs Ticagrelor
    6. FAQ's

    Prasugrel Uses:

  • In people who have had a heart attack or extreme chest pain and have been treated with angioplasty, prasugrel is used in conjunction with aspirin to avoid serious or life-threatening issues with the heart and blood vessels (a procedure to open the blood vessels that supply blood to the heart). Prasugrel belongs to a class of drugs known as antiplatelet agents. This works by preventing platelets from collecting and forming clots which can cause heart attack or stroke.
  • Prasugrel Side Effects

  • Some of the common side effects of Prasugrel are:
    • Dizziness
    • Excessive tiredness
    • Pain in the back and arms
    • Cough
  • Some of the common side effects of Prasugrel are:
    • Fever
    • Weakness
    • Paleness
    • Purple patches on the skin
    • Yellowing of skin
    • Shortness of breath
    • Irregular heartbeat
    • Headache
    • Seizures
    • Sudden weakness
    • Stomach pain
    • Nausea
    • Vomiting
    • Diarrhea
    • Blisters
    • Decreased urination
    • Rash
    • Swelling of the eyes
  • Prasugrel can cause some serious side effects. Avoid using the medicine if you feel any adverse effects and contact your doctor immediately. The doctor might change the prescribed dose or medicines looking at your side effects.
  • Precautions

  • Before taking Prasugrel talk with your doctor if you are allergic to it or any other medications. The product may contain some inactive ingredients and can cause some serious allergic reactions or problems. Before using Prasugrel talk with your doctor if you are having any medical history such as Blood disorder, bleeding problems, blood clots in the brain, liver disease and intestinal ulcers.
  • How to take Prasugrel?

  • Prasugrel is available as a tablet to be swallowed. It's taken once a day, with or without food. Prasugrel should be taken at the same time each day. Prasugrel should be taken exactly as prescribed. Do not take more or less of it, or take it more often than your doctor has prescribed. Do not crack, smash, chew, or crush the tablet; swallow it whole. Prasugrel can only help you avoid severe heart and blood vessel complications if you take it regularly. Do not quit taking prasugrel without first consulting your physician. If you stop taking Prasugrel there can be a higher risk that a person can have a heart attack or can develop a blood clot.
  • Dosage

  • Forms and Strengths
  • Tablet: 5 mg and 10 mg
  • Adult Dose for Acute Coronary Syndrome:
  • Initial dose: 60 mg orally once
  • Maintenance dose: 10 mg orally once a day
  • Geriatric Dose for Acute Coronary Syndrome:
  • 65 to less than 75 years:
  • Initial dose: 60 mg orally once
  • Maintenance dose: 10 mg orally once a day
  • Missed Dose

  • If you forget to take a dose, take it as soon as you remember. If the next dose is coming, skip the skipped dose. Take the next dose at the same time every day. To catch up, do not double the dose.
  • Overdose

  • Overdose of a drug can be accidental. If you have taken more than the prescribed Prasugrel tablets there is a chance of getting a harmful effect on your body’s functions. Overdose of a medicine can lead to some medical emergency
  • Storage

  • Direct contact with heat, air and light may damage your medicines. Exposure to medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach. Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC)
  • Prasugrel vs Ticagrelor

    Prasugrel
    Ticagrelor
    Prasugrel belongs to a class of drugs known as antiplatelet agents. This works by preventing platelets from collecting and forming clots which can cause heart attack or stroke. Ticagrelor is a blood thinner and antiplatelet drug. It increases the flow of blood into your veins. This means the blood is less likely to develop a potentially lethal blood clot.
    Some of the common side effects of Prasugrel are
    • Dizziness
    • Excessive tiredness
    • Pain in the back and arms
    • Cough
    Some of the common side effects of Ticagrelor are:
    • Nausea
    • Dizziness
    • Bleeding more easily than normal
    • Increased level of uric acid in the body

    Frequently Asked Questions:

    In people who have had a heart attack or extreme chest pain and have been treated with angioplasty, prasugrel is used in conjunction with aspirin to avoid serious or life-threatening issues with the heart and blood vessels (procedure to open the blood vessels that supply blood to the heart).
  • The Food and Drug Administration is actively evaluating prasugrel, also known as Effient, as an investigational new antiplatelet drug for clinical use. It's a thienopyridine analogue that's similar to clopidogrel and ticlopidine in structure.
  • Some of the common side effects of Prasugrel are
    • Dizziness
    • Excessive tiredness
    • Pain in the back and arm
    • Cough
    If your doctor orders you to, don't stop taking prasugrel. You may have life-threatening medical complications if you quit taking this drug too fast, such as a blood clot or a heart attack.

    Citations:

  • Prasugrel , hhttps://www.nejm.org/doi/full/10.1056/Nejmoa0706482
  • Effects of Prasugrel ,https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.109.921502