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Nabumetone

Nabumetone

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By Medicover Hospitals / 14 April 2021
Home | Medicine | Nabumetone

Nabumetone

  • Nabumetone is a type of nonsteroidal anti-inflammatory medication. It is sold under various brand names, including Relafen, Relifex, and Gambaran. The medication is a nonacidic nonsteroidal anti-inflammatory drug that is rapidly metabolized in the liver to the active metabolite, 6-methoxy-2-naphthyl acetic acid.
    1. Nabumetone Uses
    2. Nabumetone Side effects
    3. Precautions
    4. Interactions
    5. Dosage
    6. Storage
    7. Nabumetone vs Ibuprofen
    8. Frequently Asked Questions
    9. Citations

    Nabumetone Uses:

  • Nabumetone is used to treat arthritis pain, swelling, and joint stiffness. This medication is referred to as a nonsteroidal anti-inflammatory drug (NSAID). Ask your doctor about non-drug treatments and/or using other medications to treat your pain if you have a chronic condition such as arthritis.
  • How to use Nabumetone?

  • Before you start to use nabumetone, and each time you get a refill, read the Medication Guide provided by your pharmacist.
  • Take this medication orally, usually once or twice daily, with a full glass of water, as directed by your doctor. After taking this medication, do not lie down for at least 10 minutes. Take it with food, milk, or an antacid to avoid stomach upset.
  • When taking this medication on a regular basis, it may take up to two weeks before you notice the full benefits in certain conditions (such as arthritis).
  • If you take this medication on a needed basis rather than on a regular basis, keep in mind that pain medications work best when taken as soon as the first signs of pain appear. If you wait until the pain has become unbearable, the medication may not be as effective.
  • Side Effects

    • Diarrhea
    • Constipation
    • Gas or bloating
    • Dizziness
    • Headache
    • Dry mouth
    • Sores in the mouth
    • Nervousness
    • Difficulty falling asleep or staying asleep
    • Increased sweating
    • Ringing in the ears
  • Some side effects can be serious such as,
    • Unexpected weight gain
    • Shortness of breath or difficulty breathing
    • Yellowing of the skin or eyes
    • Lack of energy
    • Loss of appetite
    • Nausea

    Precautions:

  • Tell your doctor or pharmacist if you are allergic to nabumetone, aspirin, or other NSAIDs (such as ibuprofen, naproxen, or celecoxib), or if you have any other allergies.
  • Tell your doctor or pharmacist about your medical history, especially if you have: asthma, bleeding or clotting problems, nasal growths, heart disease, high blood pressure, liver disease, stroke, or stomach/intestinal/esophageal problems.
  • NSAID medications, including nabumetone, can occasionally cause kidney problems. Drink plenty of water and fluids as directed by your doctor to avoid dehydration, and notify your doctor immediately if the amount of urine changes.
  • This medication has the potential to cause stomach bleeding. The use of alcohol and tobacco on a regular basis, especially when combined with this medication, may increase your risk of stomach bleeding.
  • While taking this medication, old age people might be more likely to experience stomach or intestinal bleeding, kidney problems, heart attack, or stroke.
  • Inform your doctor if you are pregnant. This medication has the potential to harm an unborn baby and cause complications during normal labor and delivery. It is not recommended during pregnancy (from 20 weeks until delivery). If your doctor guides that you must take this medication between 20 and 30 weeks of pregnancy, you have to take the lowest effective dose for a short duration of time. This medication should not be used after 30 weeks of pregnancy.
  • It is not clear that this medication enters into breast milk or not. Before breastfeeding, talk to your doctor.
  • Interactions

  • Drug interactions can affect the way your medications work or put you at risk for serious side effects. Aliskiren, ACE inhibitors, angiotensin II receptor blockers, cidofovir, corticosteroids, lithium, methotrexate, and water pills are some products that may interact with this medication.
  • When combined with other drugs that may cause bleeding, this medication may increase the risk of bleeding. Antiplatelet drugs such as clopidogrel and blood thinners such as dabigatran/enoxaparin/warfarin are examples.
  • Missed Dose

  • It is necessary to take each dose of this medication on time. If you forget a dose, contact your doctor or pharmacist as soon as possible to arrange for a new dosing schedule. Do not double the dose.
  • Overdose

  • If someone has taken an overdose of this medicine and has serious symptoms such as trouble breathing, seek medical advice immediately. Never take more doses than what is prescribed to you by your doctor.
  • Storage:

  • The medicine must not come in contact with heat, air, light and may damage it. The medicine must be kept in a safe place and far away from children’s reach.
  • Nabumetone vs Ibuprofen

    Nabumetone
    Ibuprofen
    Nabumetone is a type of nonsteroidal anti-inflammatory medication. It is sold under a variety of brand names, including Relafen, Relifex, and Gambaran. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used as a common pain reliever used to treat a variety of aches and pains.
    It is used to treat arthritis pain, swelling, and joint stiffness. It is used to treat pain, fever, back pain, period pain, and toothache. It is also used to treat inflammation, such as strains and sprains, as well as arthritis pain.
    It works by blocking the production of chemicals in your body that cause inflammation and pain. Ibuprofen works by lowering hormones in the body that cause pain and swelling.

    Frequently Asked Questions:

    After 12 weeks of treatment, researchers discovered that nabumetone was as effective as ibuprofen and other NSAIDs in treating osteoarthritis as ibuprofen and other NSAIDs.
    Nabumetone is used for treating the pain, swelling, and stiffness associated with osteoarthritis and rheumatoid arthritis.
    Nabumetone usually starts working within a week, but in severe cases, it may take up to two weeks or longer before you start feeling better. Furthermore, it may take several weeks before you feel the full effects of nabumetone.
    Yes, it may cause weight gain because it is one of its side effects.
    Since its approval and release, nabumetone has been linked to a small number of serious hepatic adverse events (1.3 per million prescriptions), but no cases of clinically apparent liver injury due to nabumetone have been reported in the literature.
    This medication usually starts working within a week, but in severe cases, it may take up to two weeks or longer before you start feeling better.
    Yes, Nabumetone is used to treat arthritis pain, swelling, and joint stiffness.
    When used to treat severe or ongoing arthritis, this medication must be taken on a regular basis as directed by your doctor in order to be effective. This medication usually starts working within a week, but in severe cases, it may take up to two weeks or longer before you start feeling better.
    Nabumetone treatment resulted in a moderate increase in both daytime and nighttime blood pressure, with no changes in biological diurnal variation.
    Avoid consuming alcoholic beverages. It will raise your chances of experiencing stomach bleeding. While taking nabumetone 500mg, avoid taking aspirin. Before taking any other pain medications, fever, swelling, or flu symptoms, consult your doctor.

    Citations:

  • Nabumetone, https://link.springer.com/article/10.2165/00003495-200464200-00004
  • Nabumetone in the treatment, https://www.sciencedirect.com/science/article/abs/pii/000293438790595X