Mirtazapine: Uses, Side Effects, Dosage and Warnings
Written by Medicover Team and Medically Reviewed by Dr Siva Anoop Yella, Psychiatry
Mirtazapine is an antidepressant that helps improve mood and emotional well-being in people with depression.
It is available as oral tablets and orally disintegrating tablets and is effective in managing major depressive disorder. As the brand-name drugs Remeron (immediate-release tablet) and Remeron soltab are available, Mirtazapine (orally disintegrating tablet).
Mirtazapine primarily treats depression by balancing brain chemicals to improve mood and reduce symptoms. It is mainly prescribed to help manage major depressive disorder and improve feelings of well-being.
Mirtazapine works by restoring the natural balance of neurotransmitters in the brain, mainly serotonin and norepinephrine.
This helps improve communication between nerve cells, which lifts mood and reduces depressive symptoms. It also affects receptors related to sleep and appetite.
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Overdose of a drug can be accidental. If you have taken more than the prescribed Mirtazapine tablets there is a chance of getting a harmful effect on your body's functions. Overdose of a medicine can lead to some medical emergency.
Like all medicines, Mirtazapine can cause side effects, but not everyone gets them.
If you have any of these serious symptoms immediately contact your doctor for further assistance.
Before taking Mirtazapine talk with your doctor if you are allergic to it or any other medications. The product may contain some inactive ingredients which can cause some serious allergic reactions or some other problems.
Use caution if you have:
Mirtazapine can cause some serious conditions which can affect the heart rhythm i. e. QT prolongation. QT prolongation will rarely cause some serious and irregular heartbeat which can need medical attention.
Mirtazapine may increase the risk of seizures or make existing seizure conditions worse. If you experience a seizure while taking this medicine:
If you have kidney issues or a history of kidney failure, you will not be able to get your body off this medicine properly.
This will increase the body's mirtazapine content and cause further side effects.
People with glaucoma or other serious eye problems should use Mirtazapine with caution.
It may increase eye pressure and worsen symptoms. Always consult your eye specialist before using this medicine.
Mirtazapine can pass into breast milk and may affect your baby. Talk to your doctor if:
Your doctor can help you decide what's safest for both you and your child.
Are There Any Age Restrictions for Using Mirtazapine?
Alcohol, Food, and Drug Interactions
| Mirtazapine | Sertraline |
|---|---|
| Mirtazapine works as an antidepressant. It comes as an oral instant-release tablet or a tablet that disintegrates (dissolves) orally. | Sertraline is an antidepressant which belongs to the group of selective serotonin reuptake inhibitors. It affects the chemical in the brain which can be unbalanced in people with depression, panic and anxiety. |
| Mirtazapine is used for the treatment of depression. The medication helps in improving mood and feelings of well-being. | Sertraline can improve the mood, sleep, appetite and energy level. The medication also helps in decreasing the fear, anxiety and the number of panic attacks. |
Some of the common side effects of Mirtazapine are:
|
Some of the serious side effects of Sertraline are:
|

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040-68334455Mirtazapine is a new antidepressant that displays activity in both noradrenergic and serotonergic. For treating moderate to severe depression, it is at least as effective as the older antidepressants.
Mirtazapine (Remeron) has a much more sedative effect, minimizing its ability to exacerbate initial anxiety in general.
Within the first 1-2 weeks, sleep, energy, or appetite can show some improvement. A significant early indication that the drug is working may be a change in these physical symptoms.
The medication can also cause Agitation, violence and forgetfulness. If you drink alcohol, just drink small quantities of alcohol to see how you feel. Don't stop taking medicine with you. Inform your doctor immediately if you have a headache, sore throat or sore mouth when taking mirtazapine.
Antidepressants such as mirtazapine help to raise the mood progressively so that you feel better. You may find that you sleep better and get on with people more easily because you're less nervous. Hopefully, you'll take stuff that used to bother you in your stride.
Taking paracetamol and ibuprofen with mirtazapine is safe. If taken in conjunction with mirtazapine, strong painkillers such as codeine, co-codamol and dihydrocodeine can make you feel more sleepy.
Yes, mirtazapine is often prescribed to reduce anxiety by balancing brain chemicals that affect mood and stress.
The max daily dose is usually 45 mg, but your doctor will decide the right dose for you based on your condition.
Mirtazapine is an antidepressant that also helps anxiety and sleep; escitalopram is an SSRI mainly used for depression and anxiety with fewer sedative effects.
Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.