Mirtazapine is an antidepressant that helps improve mood and emotional well-being in people with depression.

It is available as oral tablets and orally disintegrating tablets and is effective in managing major depressive disorder. As the brand-name drugs Remeron (immediate-release tablet) and Remeron soltab are available, Mirtazapine (orally disintegrating tablet).

What are the Uses of Mirtazapine Tablet?

Mirtazapine primarily treats depression by balancing brain chemicals to improve mood and reduce symptoms. It is mainly prescribed to help manage major depressive disorder and improve feelings of well-being.

Conditions Treated

  • Major depressive disorder
  • Sometimes used off-label for anxiety or sleep disorders

How Does Mirtazapine Tablet Work (Mechanism of Action)?

Mirtazapine works by restoring the natural balance of neurotransmitters in the brain, mainly serotonin and norepinephrine.

This helps improve communication between nerve cells, which lifts mood and reduces depressive symptoms. It also affects receptors related to sleep and appetite.

How to take the Dosage of Mirtazapine?

  • Mirtazapine is available as a regular tablet and a disintegrating tablet taken by mouth.
  • It is usually taken once a day at bedtime.
  • Mirtazapine tablets can be taken with or without food.
  • To take the disintegrating tablet, open the blister pack with dry hands.
  • Place the tablet on your tongue, where it will disintegrate and can be swallowed with saliva.
  • No water is needed to swallow the disintegrating tablet.
  • Do not store the disintegrating tablet after removing it from the blister pack.
  • Do not break the disintegrating tablets.

Get a second opinion from trusted experts and makeconfident, informed decisions.

Get Second Opinion

What are the Dosage Forms and Strengths?

  • Generic: Mirtazapine
  • Form: oral immediate-release tablet ( 7.5 mg, 15 mg, 30 mg, 45 mg)
  • Form: orally disintegrating tablet (15 mg, 30 mg, 45 mg)
  • Brand: Remeron
  • Form: oral immediate-release tablet (15 mg, 30 mg, 45 mg)
  • Brand: Remeron SolTab
  • Form: orally disintegrating tablet (15 mg, 30 mg, 45 mg)

What is the Dosage for Depression?

  • Starting dosage: 15 mg should be taken once per day
  • Dosage increases: After seeing the improvements the doctor will slowly increase the dosage every 1-2 weeks.

What Should One Do if Missed a Dose of Mirtazapine?

  • Missing one or two doses of Mirtazapine usually won't have a significant effect on your body.
  • A skipped dose typically causes no major problems for most people.
  • However, some medications require timely intake to remain effective.
  • Missing a dose may cause sudden chemical changes in your body in certain cases.
  • Sometimes, doctors may advise you to take the missed dose as soon as possible, depending on the medication.

What Should be Done in Case of an Overdose of Mirtazapine?

Overdose of a drug can be accidental. If you have taken more than the prescribed Mirtazapine tablets there is a chance of getting a harmful effect on your body's functions. Overdose of a medicine can lead to some medical emergency.

What are the Side Effects of Mirtazapine Tablet?

Like all medicines, Mirtazapine can cause side effects, but not everyone gets them.

Common Side Effects of Mirtazapine

Serious Side Effects of Mirtazapine

If you have any of these serious symptoms immediately contact your doctor for further assistance.

Precautions for Mirtazapine

Before taking Mirtazapine talk with your doctor if you are allergic to it or any other medications. The product may contain some inactive ingredients which can cause some serious allergic reactions or some other problems.

Use caution if you have:

Mirtazapine can cause some serious conditions which can affect the heart rhythm i. e. QT prolongation. QT prolongation will rarely cause some serious and irregular heartbeat which can need medical attention.

What are the Allergy Warnings?

  • Trouble breathing
  • Swelling of the face, tongue, eyes and mouth
  • Severe rash with swelling
  • Painful reddening of the skin
  • Itchy welts

Warning for People with Certain Health Conditions

For people with a history of Mania or Bipolar disorder

  • If you have a history of mania or bipolar disorder, consult your doctor before using Mirtazapine.
  • This medicine can trigger mixed or psychotic episodes in some individuals.

For people with Seizures

Mirtazapine may increase the risk of seizures or make existing seizure conditions worse. If you experience a seizure while taking this medicine:

  • Contact your doctor immediately.
  • Your doctor may suggest stopping the medicine or gradually reducing the dose to prevent withdrawal symptoms.

For people with Heart Problems

  • If you have had a heart attacks, angina (chest pain), or stroke, speak with your doctor first.
  • Mirtazapine can lower blood pressure, which may worsen certain heart issues.

For people with Kidney problems

If you have kidney issues or a history of kidney failure, you will not be able to get your body off this medicine properly.

This will increase the body's mirtazapine content and cause further side effects.

For people with Glaucoma or Eye problems

People with glaucoma or other serious eye problems should use Mirtazapine with caution.

It may increase eye pressure and worsen symptoms. Always consult your eye specialist before using this medicine.

For women who are breastfeeding

Mirtazapine can pass into breast milk and may affect your baby. Talk to your doctor if:

  • You are currently breastfeeding.
  • You are planning to stop breastfeeding.
  • You are considering stopping the medication.

Your doctor can help you decide what's safest for both you and your child.

Are There Any Age Restrictions for Using Mirtazapine?

  • Mirtazapine is generally prescribed for adults.
  • Its safety and effectiveness in children under 18 years have not been fully established, so it'should be used only under strict medical guidance in younger patients.

Alcohol, Food, and Drug Interactions

  • Avoid alcohol while taking Mirtazapine, as it may increase drowsiness and other side effects, affecting your safety and alertness.
  • This medicine may interact with other drugs like other antidepressants, blood pressure medicines, or sedatives.
  • Always inform your doctor about all supplements or herbal products you use to prevent interactions.

How to Store a Mirtazapine Tablet?

  • Direct contact with heat, air and light may damage your medicines. The exposure of medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children's reach.
  • Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).
  • Consult your doctor before taking Mirtazapine. If you experience side effects, seek immediate medical help or visit the nearest hospital.

Mirtazapine vs Sertraline

Mirtazapine Sertraline
Mirtazapine works as an antidepressant. It comes as an oral instant-release tablet or a tablet that disintegrates (dissolves) orally. Sertraline is an antidepressant which belongs to the group of selective serotonin reuptake inhibitors. It affects the chemical in the brain which can be unbalanced in people with depression, panic and anxiety.
Mirtazapine is used for the treatment of depression. The medication helps in improving mood and feelings of well-being. Sertraline can improve the mood, sleep, appetite and energy level. The medication also helps in decreasing the fear, anxiety and the number of panic attacks.
Some of the common side effects of Mirtazapine are:
  • Sleepiness
  • Increased appetite
  • Weight gain
  • Dry mouth
  • Constipation
Some of the serious side effects of Sertraline are:
  • Seizure
  • Blurred
  • vision
  • Headache

References

Mirtazapine
Mirtazapine: MedlinePlus Drug Information
Mirtazapine - StatPearls - NCBI Bookshelf
Book Doctor Appointment
Book Free Appointment

Still have questions? Speak with our experts now!

040-68334455

Frequently Asked Questions

Mirtazapine is a new antidepressant that displays activity in both noradrenergic and serotonergic. For treating moderate to severe depression, it is at least as effective as the older antidepressants.

Mirtazapine (Remeron) has a much more sedative effect, minimizing its ability to exacerbate initial anxiety in general.

Within the first 1-2 weeks, sleep, energy, or appetite can show some improvement. A significant early indication that the drug is working may be a change in these physical symptoms.

The medication can also cause Agitation, violence and forgetfulness. If you drink alcohol, just drink small quantities of alcohol to see how you feel. Don't stop taking medicine with you. Inform your doctor immediately if you have a headache, sore throat or sore mouth when taking mirtazapine.

Antidepressants such as mirtazapine help to raise the mood progressively so that you feel better. You may find that you sleep better and get on with people more easily because you're less nervous. Hopefully, you'll take stuff that used to bother you in your stride.

Taking paracetamol and ibuprofen with mirtazapine is safe. If taken in conjunction with mirtazapine, strong painkillers such as codeine, co-codamol and dihydrocodeine can make you feel more sleepy.

Yes, mirtazapine is often prescribed to reduce anxiety by balancing brain chemicals that affect mood and stress.

The max daily dose is usually 45 mg, but your doctor will decide the right dose for you based on your condition.

Mirtazapine is an antidepressant that also helps anxiety and sleep; escitalopram is an SSRI mainly used for depression and anxiety with fewer sedative effects.


Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.

Book Appointment Second Opinion WhatsApp Health Packages Find Doctors

Feeling unwell?

Request a callback!