Mirtazapine

Mirtazapine works as an antidepressant. It comes as an oral instant-release tablet or a tablet that disintegrates (dissolves) orally. As the brand-name drugs Remeron (immediate-release tablet) and Remeron soltab are available, Mirtazapine (orally disintegrating tablet). Both forms are available as generic medicines as well. The medication helps in treating major depressive disorder.


Uses

Mirtazapine is used for the treatment of depression. The medication helps in improving mood and feelings of well-being. Mirtazapine is an antidepressant which works by restoring the balance of natural chemicals in the brain


Mirtazapine Side effects

Some of the common side effects of Mirtazapine are:

Some of the serious side effects of Mirtazapine are:

  • Trouble in sleeping
  • Aggressive or Violent thoughts
  • Mood swings
  • Reckless behaviour
  • Fever
  • Chills
  • Sore throat
  • Agitation
  • Hallucinations
  • Irregular heartbeat
  • High blood pressure
  • Nausea
  • Vomiting

If you have any of these serious symptoms immediately contact your doctor for further assistance. In any case, due to Mirtazapine if you get any kind of reactions in your body try avoiding it.

A doctor advised you to take the medicines by seeing your problems and the benefits of this medicine are greater than the side effects. Majority of the people who use this medicine don’t show any side effects. Get medical help immediately if you get any serious Mirtazapine side effects.


Precautions

Before taking Mirtazapine talk with your doctor if you are allergic to it or any other medications. The product may contain some inactive ingredients which can cause some serious allergic reactions or some other problems.

Before taking Mirtazapine, talk with your doctor if you are having any medical history such as:

  • Psychiatric disorders
  • Liver disease
  • Kidney disease
  • Seizures
  • High blood cholesterol
  • Heart disease
  • Stroke
  • Severe loss of body fluids
  • Low blood pressure

Mirtazapine can cause some serious conditions which can affect the heart rhythm i.e. QT prolongation. QT prolongation will rarely cause some serious and irregular heartbeat which can need medical attention.

How to take Mirtazapine?

Mirtazapine comes as a tablet that can be taken by mouth and as a disintegrating tablet. It is normally taken at bedtime, once a day. Mirtazapine tablets can be taken with or without food. Open the dry-handed blister pack to take a mirtazapine disintegrating tablet and put the tablet on your tongue. On the tongue, the tablet may disintegrate and could be swallowed with saliva. To swallow the disintegrating tablets, no water is needed. It cannot be kept until the tablet is extracted from the blister pack. Do not break the disintegrating tablets of mirtazapine.


Dosage Forms and Strengths

Generic: Mirtazapine

  • Form: oral immediate-release tablet ( 7.5 mg, 15 mg, 30 mg, 45 mg)
  • Form: orally disintegrating tablet (15 mg, 30 mg, 45 mg)

Brand: Remeron

  • Form: oral immediate-release tablet (15 mg, 30 mg, 45 mg)

Brand: Remeron SolTab

  • Form: orally disintegrating tablet (15 mg, 30 mg, 45 mg)

Dosage for Depression

Starting dosage: 15 mg should be taken once per day

Dosage increases: After seeing the improvements the doctor will slowly increase the dosage every 1-2 weeks.


Missed Dose

Missing one or two-dose of Mirtazapine won’t show any effect on your body. The skipped dose causes no problem. But with some medication, it won’t work if you don’t take the dosage on time. If you miss a dose some sudden chemical change may affect your body. In some cases, your doctor would advise you to take the prescribed medicine as soon as possible if you have missed the dose.


Overdose

Overdose of a drug can be accidental. If you have taken more than the prescribed Mirtazapine tablets there is a chance of getting a harmful effect on your body’s functions. Overdose of a medicine can lead to some medical emergency.


Allergy Warnings

  • Trouble breathing
  • Swelling of the face, tongue, eyes and mouth
  • Severe rash with swelling
  • Painful reddening of the skin
  • Itchy welts

Warning for People with Certain Health Conditions

For people with a history of Mania or Bipolar disorder

Speak to your doctor to find out if this prescription is suitable for you. Mirtazapine can cause an episode that is mixed or psychotic.

For people with Seizures

Speak to your doctor to find out if this prescription is suitable for you. The condition can be made worse by this medicine. Speak to your physician if you have a seizure while taking mirtazapine. If you should stop taking it, they will decide. You may need to stop taking this medication right away or to prevent withdrawal effects, the dose may slowly be reduced over time.

For people with Heart Problems

Speak to the doctor if you have a history of such heart attacks as to whether this medicine is appropriate for you. Angina (chest pain), heart attack, or stroke are among these heart issues. Low blood pressure can be caused by mirtazapine, which can make heart attacks worse.

For people with Glaucoma or Eye problems

If you have kidney issues or a history of kidney failure, you will not be able to get your body off this medicine properly. This will increase the body's mirtazapine content and cause further side effects.

For women who are breastfeeding

For a child who is breastfed, Mirtazapine can transfer into breast milk and can cause side effects. If you're breastfeeding your kid, speak to your doctor. If you want to stop breastfeeding or stop taking this drug, you will need to decide.


Storage

Direct contact with heat, air and light may damage your medicines. The exposure of medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach.

Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).

Before taking Mirtazapine consult your Doctor. In case you face any problems or get any side effects after taking Mirtazapine, rush immediately to your nearby hospital or consult your doctor for better treatment. Carry your medications always in your bag while travelling to avoid any immediate emergencies. Follow your prescription and follow your Doctor advice whenever you take Mirtazapine.


Fondaparinux vs Heparin:

Mirtazapine

Sertraline

Mirtazapine works as an antidepressant. It comes as an oral instant-release tablet or a tablet that disintegrates (dissolves) orally. Sertraline is an antidepressant which belongs to the group of selective serotonin reuptake inhibitors. It affects the chemical in the brain which can be unbalanced in people with depression, panic and anxiety.
Mirtazapine is used for the treatment of depression. The medication helps in improving mood and feelings of well-being. Sertraline can improve the mood, sleep, appetite and energy level. The medication also helps in decreasing the fear, anxiety and the number of panic attacks.
Some of the common side effects of Mirtazapine are:
  • Sleepiness
  • Increased appetite
  • Weight gain
  • Dry mouth
  • Constipation
Some of the serious side effects of Sertraline are:
  • Seizure
  • Blurred
  • vision
  • Headache

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Frequently Asked Questions

What side effects does mirtazapine have?

Some of the common side effects of Mirtazapine are:

  • Sleepiness
  • Increased appetite
  • Weight gain
  • Dry mouth
  • Constipation

Is mirtazapine a strong antidepressant?

Mirtazapine is a new antidepressant that displays activity in both noradrenergic and serotonergic. For treating moderate to severe depression, it is at least as effective as the older antidepressants.

Does mirtazapine calm you down?

Mirtazapine (Remeron) has a much more sedative effect, minimizing its ability to exacerbate initial anxiety in general.

How long does it take for mirtazapine to kick in for sleep?

Within the first 1-2 weeks, sleep, energy, or appetite can show some improvement. A significant early indication that the drug is working may be a change in these physical symptoms.

Does mirtazapine make you angry?

The medication can also cause Agitation, violence and forgetfulness. If you drink alcohol, just drink small quantities of alcohol to see how you feel. Don't stop taking medicine with you. Inform your doctor immediately if you have a headache, sore throat or sore mouth when taking mirtazapine.

How does mirtazapine make you feel?

Antidepressants such as mirtazapine help to raise the mood progressively so that you feel better. You may find that you sleep better and get on with people more easily because you're less nervous. Hopefully, you'll take stuff that used to bother you in your stride.

What painkillers can I take with mirtazapine?

Taking paracetamol and ibuprofen with mirtazapine is safe. If taken in conjunction with mirtazapine, strong painkillers such as codeine, co-codamol and dihydrocodeine can make you feel more sleepy.


Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.