Metaxalone: Uses, Dosage, Side Effects and Mechanism of Action
Written by Medicover Team and Medically Reviewed by Dr Praveen Sodavarapu, Orthopedics
Metaxalone is an analgesic that relaxes the muscles. It helps relieve pain by blocking pain signals from reaching your brain.
Metaxalone is used to treat skeletal muscle conditions such as pain or injury in conjunction with rest and physical therapy.
Metaxalone mainly treats muscle pain and spasms, aiding healing and improving comfort and mobility during recovery from injuries.
Metaxalone 800 mg works by blocking nerve signals that carry pain sensations to the brain, helping reduce the feeling of muscle pain and spasms.
Proper dosing depends on your condition, age, and doctor's advice. Always follow your prescription carefully to avoid side effects.
Get a second opinion from trusted experts and makeconfident, informed decisions.
Get Second OpinionMost side effects are mild, but some may require immediate medical attention.
If you experience any of the symptoms mentioned above, call your doctor immediately.
Certain groups should exercise caution when using Metaxalone.
Are There Any Age Restrictions for Using Metaxalone?
Metaxalone 400 mg or 800 mg tablets may not be suitable for very young children or older adults without proper medical supervision.
Doctors typically prescribe Metaxalone based on age, weight, and health condition. Always follow your healthcare provider's advice regarding its use in children or the elderly.
Alcohol or Food Interactions with Metaxalone
Food and alcohol may change how Metaxalone works in your body or increase the risk of side effects.
Metaxalone may interact with other medications, supplements, or herbal products, so tell your doctor about everything you take.
| Metaxalone | Tolperisone |
|---|---|
| Metaxalone is an analgesic that relaxes the muscles. | Tolperisone (Mydocalm) is a centrally-acting skeletal muscle relaxant used to treat increased muscle tone caused by neurological diseases. |
| It is used to treat skeletal muscle conditions such as pain or injury in conjunction with rest and physical therapy. | Tolperisone is used to relax muscles. It is employed in the treatment of acute musculoskeletal pain. |
| It works by preventing nerve impulses (or pain sensations) from reaching the brain. | It works on the brain and spinal cord centers to relieve muscle stiffness or spasm without reducing strength. This reduces pain and improves muscle movement. |

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040-68334455It is a muscle relaxant that is used to relax the muscles and relieve pain or discomfort caused by strains, sprains, and other muscle injuries in conjunction with rest, physical therapy, and other measures.
This medication may make you dizzy, drowsy, or less alert than usual. These effects may be amplified if you take this medication with food.
Based on clinical studies, metaxalone (Skelaxin) has the fewest reported side effects and the lowest sedation potential of the muscle relaxants when taken as 800 mg tablets three to four times a day. Simply put, it is the most well-tolerated muscle relaxant.
Metaxalone has a 1-hour onset of action, a 2 to 3-hour plasma half-life, and a 4 to 6-hour duration of action. This medication is available in 400-mg tablets with a recommended dose of 800 mg three or four times daily.
Yes, Metaxalone is a muscle relaxant often prescribed for back pain. It helps relieve muscle spasms and discomfort when used with rest and physical therapy. Always use it under medical supervision.
Metaxalone is contraindicated in patients with severely impaired hepatic and renal function. Because methylmalonic is metabolized by the liver and then eliminated by the kidney, both the parent drug and its metabolites may accumulate in such patients.
Metaxalone belongs to the drug class skeletal muscle relaxants and is used to treat muscle spasms. The FDA has not classified the drug as safe to use during pregnancy. Under the Controlled Substances Act, metaxalone 800 mg is not a controlled substance.
Metaxalone is usually prescribed for short-term use, typically up to 2-3 weeks, unless your doctor advises otherwise based on your condition.
Metaxalone causes less drowsiness and has fewer sedative effects, while Cyclobenzaprine is more sedating and often used at bedtime for muscle spasms.
Skeletal muscle relaxants such as Skelaxin (metaxalone) and Flexeril (cyclobenzaprine) are used to treat painful muscle spasms. Similar Skelaxin and Flexeril side effects include drowsiness, dizziness, headache, nausea, and stomach upset or pain.
Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.