What is Desloratadine?
Desloratadine is a second-generation tricyclic antihistamine that functions as a potent H1 antagonist in the peripheral nervous system. It's loratadine’s active descarboethoxy metabolite (second-generation histamine). Since desloratadine does not readily reach the central nervous system, it has a long-lasting effect and does not cause drowsiness.
Desloratadine is a medicine that needs a prescription. It's available as a tablet, a disintegrating tablet, or an oral syrup. Both forms are taken orally. Clarinex is a brand-name drug that contains desloratadine. It can also be obtained as a generic drug.
Desloratadine uses
Desloratadine is used to treat hay fever and allergy symptoms in adults and children, such as sneezing, runny nose, and swollen, itchy, weeping eyes. It's also used to alleviate the itching and rash associated with urticaria (hives; red, itchy raised areas of the skin). Desloratadine belongs to the antihistamine family of medicines. The medications work by blocking histamine which is a substance in the body that will cause allergic symptoms.
Desloratadine Side Effects
Some of the common side effects of Desloratadine are:
- Sore throat
- Dry mouth
- Muscle pain
- Tiredness
- Sleepiness
- Menstrual pain
Some of the serious side effects of Desloratadine are:
- Skin rash
- Itching
- Hives
- Swelling of the lips, tongue or throat
Keep in mind that your doctor approved this drug because he or she feels the value to you outweighs the risk of side effects. The majority of people who take this drug do not experience any significant side effects. If you experience symptoms of infection when taking this medicine, such as a persistent sore throat, persistent cough, fever, chills, night sweats, difficulty breathing, painful or repeated urination, irregular vaginal discharge, or white patches in your mouth, contact your doctor right away.
Precautions
Before taking Desloratadine talk with your doctor if you are allergic to it or any other medications. The product may contain some inactive ingredients which can cause some serious allergic reactions or some other serious problems. Before using Desloratadine talk with your doctor if you are having any medical history such as Kidney disease, liver disease, abdominal pain and stomach ulcers.
How to take Desloratadine?
Desloratadine is available in three forms: pill, oral solution (liquid), an orally disintegrating tablet. It's taken once a day, with or without food. Do not use a household spoon to precisely determine the correct amount of solution for each dose; instead, use a measuring system (dropper or oral syringe). Peel back the foil wrapping with dry hands to take the orally disintegrating tablet. Take out the tablet and put it on your tongue right away. The tablet can dissolve easily and can be swallowed whole.
Dosage Desloratadine
Forms and Strengths
Generic:Desloratadine
Form: oral tablet (5 mg)
Form: oral disintegrating tablet (2.5 mg, 5 mg)
Brand:Clarinex
Form: oral tablet (5 mg)
Brand:Clarinex
Form: orally disintegrating tablet (2.5 mg, 5 mg)
Dosage for seasonal allergic rhinitis
Adult dosage (ages 18 years and older): 5 mg tablet once a day
Dosage for perennial allergic rhinitis
Adult dosage (ages 18 years and older): 5 mg tablet once a day
Dosage for chronic itching due to hives (idiopathic urticaria)
Adult dosage (ages 18 years and older): 5 mg tablet once a day
Interactions
Drug interactions can transform the way your medications function or put you at risk for serious side effects. Disopyramide, anticholinergics (including atropine, belladonna alkaloids, and scopolamine), certain blood pressure medications (such as clonidine, guanadrel, and guanethidine), digoxin, thyroid supplements, and valproic acid are examples of products that may interact with this medication.
Using MAO inhibitors in conjunction with this medication may result in a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors. Most MAO inhibitors should also be avoided for two weeks prior to and following treatment with this medication. Consult your doctor about when to begin or stop taking this medication.
Missed Dose
As soon as you remember, take your dose. Take just one dose if you recall just a few hours before the next scheduled dose. Never try to make up for missed doses by taking two at once. This could have dangerous consequences.
Overdose
Overdose of a drug can be accidental. If you have taken more than the prescribed Desloratadine tablets there is a chance of getting a harmful effect on your body’s functions. Overdose of a medicine can lead to some medical emergency.
Warnings for some serious health conditions
For people with Liver Disease
If you have liver problems, you might be unable to adequately process this medicine. You're more likely to experience side effects as a result of this. This medication could be prescribed at a lower dose by your doctor.
For people with Kidney problems
If you have kidney issues, you might not be able to completely remove this medicine from your body. You're more likely to experience side effects as a result of this. This medication could be prescribed at a lower dose by your doctor.
Pregnant Women
Desloratadine can only be used during breastfeeding if absolutely necessary, according to the manufacturer. Desloratadine is not considered to be safe to take during pregnancy. If you are pregnant or planning to pregnant then talk with your doctor before taking Desloratadine.
Breastfeeding
According to the drug's maker, you cannot breastfeed when taking Desloratadine. Desloratadine may be passed on to a breastfed infant by human breast milk. However, there isn't enough information to decide if the sum is safe or could hurt the child. Consult your doctor if you intend to breastfeed or are actually doing so. They will advise you on how to feed your child properly and what care options are available.
Storage
Direct contact with heat, air and light may damage your medicines. Exposure to medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach. Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).
Desloratadin vs Cetrizine
Desloratadine |
Cetirizine |
|---|---|
| Desloratadine is a second-generation tricyclic antihistamine that functions as a potent H1 antagonist in the peripheral nervous system. | Cetirizine tablets are an antihistamine that is used for relieving the allergy symptoms such as watery eyes, runny nose, itching eyes/ nose, hives and itching |
| Desloratadine is used to treat hay fever and allergy symptoms in adults and children, such as sneezing, runny nose, and swollen, itchy, weeping eyes. | Cetirizine does not prevent hives but it treats serious allergic reaction |
Some of the common side effects of Desloratadine are:
|
Some of the common side effects of Stelara are:
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Citations
Safety and efficacy of desloratadine 5 mg in asthma patients with seasonal allergic rhinitis and nasal congestion, ID:10.1016/S1081-1206(10)62086-8Desloratadine and depression, a drug safety signal based on worldwide spontaneous reporting of side effects, ID:10.3316/INFORMIT.505361890690497
