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Aldactone

Aldactone

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By Medicover Hospitals / 22 Feb 2021
Home | Medicine | Aldactone
  • Aldactone (spironolactone) is a potassium-sparing diuretic used in congestive heart failure, liver cirrhosis, and kidney disease to drain excess fluid from the body. It can also be used in conjunction with other medications to treat low potassium (hypokalemia) and high blood pressure caused by diuretics. Aldactone and its active metabolites are unique pharmacological aldosterone antagonists, acting primarily at the aldosterone-dependent sodium-potassium exchange site in the distal convoluted renal tubule through competitive binding of receptors. Aldactone induces the excretion of increased concentrations of sodium and water, while potassium is retained.
    1. Aldactone Uses
    2. Side effects
    3. Precautions
    4. Dosage
    5. Aldactone vs Spironolactone
    6. FAQ's

    Aldactone Uses:

  • Aldactone is used to treat elevated blood pressure (hypertension), heart failure or hypokalemia (low potassium levels in the blood). In people with congestive heart failure, liver cirrhosis, or a kidney disease called nephrotic syndrome, Aldactone also treats fluid retention (edema). Aldactone is also used for the diagnosis or treatment of a disorder in which your body has too much aldosterone. To help control the salt and water balance in the body, aldosterone is a hormone released by your adrenal glands.
  • Aldactone Side Effects

  • Some of the common side effects of Aldactone are:
    • Dizziness
    • Drowsiness
    • Headache
    • Itching
    • Menstrual problems
    • Nausea
    • Vomiting
    • Stomach cramps
  • Some of the serious side effects of Aldactone are:
    • Allergic reaction
    • Electrolyte imbalance
    • Gynecomastia
    • Skin allergies

    Precautions

  • Before taking Aldactone talk with the doctor if you are allergic to it or any other medications. The drugs may contain some inactive ingredients which can cause some serious allergic reactions and some other serious problems.
  • Before using Aldactone talk with your doctor if you are having any medical history such as: Kidney problems, Liver problems, untreated mineral imbalance and decreased adrenal gland function.
  • How to take Aldactone?

  • Shake the bottle just before each dose if you are using the liquid form of this drug. Using a special measuring device/spoon, measure the dose carefully. Do not use a household spoon, because the correct dose may not be given to you. With or without food, you may take the liquid form of this medication, but it is important to choose one way and take it the same way with every dose.
  • Dosage Forms and Strengths

  • Aldactone: 25 mg, 50 mg and 100 mg
  • Dosage for Heart Failure

  • The typical starting dosage would be 25 mg once in a day. Looking at the benefits of the dosage the doctor may increase the dosage to 50 mg once in a day.
  • Dosage for High Blood Pressure

  • For Hypertension the typical Aldactone dosage is 25 to 100 mg.
  • Dosage for High Blood Pressure

  • For Hypertension the typical Aldactone dosage is 25 to 100 mg.
  • Dosage for Edema

  • Aldactone 100 mg is the typical initial dosage.
  • Missed Dose

  • Try to take it as soon as you remember, if you miss a dose. But if your next dose is almost due, simply skip the skipped dose and wait until the next daily dose is taken. You are not allowed to "double-up" or take two doses at once. This can raise the likelihood that Aldactone may have side effects.
  • Overdose

  • Overdose of a drug can be accidental. If you have taken more than the prescribed Aldactone tablets there is a chance of getting a harmful effect on your body’s functions. Overdose of a medicine can lead to some medical emergency.
  • Allergic Reactions

  • As for other medications, after taking Aldactone, certain individuals can have an allergic reaction. How many times this side effect may have occurred in clinical trials is unclear. This may involve signs of a mild allergic reaction:
    • Skin rash
    • Itchiness
    • Flushing (warmth, swelling and redness in the skin)
    • Fever

    Storage

  • Direct contact with heat, air and light may damage your medicines. Exposure to medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach. Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).
  • Aldactone vs Spironolactone

    Aldactone
    Spironolactone
    Aldactone (spironolactone) is a potassium-sparing diuretic used in congestive heart failure, liver cirrhosis, and kidney disease to drain excess fluid from the body. Spironolactone is a potassium-sparing diuretic that helps in preventing the body from absorbing too much salt and also keeps the potassium levels from getting very low
    Aldactone is also used for the diagnosis or treatment of a disorder in which your body has too much aldosterone. The medication is also used for treating swelling that is caused by various conditions and by removing excess fluid and improving symptoms like breathing problems.
    Some of the common side effects of Aldactone are:
    • - Dizziness
    • - Drowsiness
    • - Headache
    • - Itching
    • - Menstrual problems
    The most common side effects of Spironolactone are:
    • - Muscle weakness, pain and cramps
    • - Inability to move arms and legs
    • - Irregular heartbeat
    • - Confusion

    Frequently Asked Questions:

    Lowering high blood pressure helps to avoid strokes, kidney complications, and heart attacks. It is also used to treat swelling (edema) caused by some conditions by removing excess fluid and improving symptoms such as breathing issues (such as heart failure, liver disease).
    Aldactone works by limiting hormonal changes that can trigger the production of breakouts. Usually, androgen hormones, including testosterone, are known to be male hormones. Androgens, however, are also found in the female body, but at lower levels. More androgen hormones than required are developed by some women.
    Aldactone works against a hormone called aldosterone by acting against it. Too much aldosterone allows the kidneys to maintain elevated levels of sodium (a mineral) and water, while too much potassium is eliminated from the body. The effects of aldosterone are acted against by Aldactone.
    In patients with low to no salt in their body or in those taking other blood pressure medicines, Aldactone can worsen kidney function (eg, ARB, ACE inhibitor). If you have questions about this, talk to your doctor.
    It is a steroid that blocks and has some estrogen-like effects on the effects of the hormones aldosterone and testosterone. Aldactone belongs to a class of drugs known as diuretics that are potassium-sparing.
    Some of the common side effects of Aldactone are:
    • Dizziness
    • Drowsiness
    • Headache
    • Itching
    • Menstrual problems

    Citations:

  • Aldactone , https://www.ahajournals.org/doi/full/10.1161/01.CIR.102.22.2700
  • Effects of Aldactone ,https://gut.bmj.com/content/4/1/16.abstract