Understand Hemangiosarcoma Symptoms and Treatment

Written by Medicover Team and Medically Reviewed by Dr Shruti Surushe , Oncologists



Hemangiosarcoma is a rare and aggressive cancer that develops from the cells lining blood vessels. It can affect the skin, liver, spleen, heart, or other organs, causing symptoms that vary depending on the tumor's location. Early diagnosis and prompt treatment, including surgery, chemotherapy, or radiation therapy, help manage the disease, reduce complications, and improve long-term outcomes.


What Are the Types of Hemangiosarcoma?

Hemangiosarcoma is classified based on the organ or tissue where it develops.

  • Cutaneous Angiosarcoma: Affects the skin, commonly on the scalp or face.
  • Soft Tissue Angiosarcoma: Develops in muscles or connective tissues.
  • Cardiac Angiosarcoma: Arises in the heart, usually the right atrium.
  • Hepatic Angiosarcoma: Occurs in the liver.
  • Breast Angiosarcoma: May develop primarily or after radiation therapy.

What Are the Symptoms of Hemangiosarcoma?

Hemangiosarcoma, a type of cancer that originates in blood vessels, can cause various symptoms in affected individuals. Common signs may include weakness, lethargy, pale gums, decreased appetite, weight loss, and abdominal distension due to internal bleeding.

In some cases, patients may also experience difficulty breathing, coughing, and collapse. Early detection and prompt medical attention are crucial in managing this aggressive cancer. If you notice any of these symptoms in yourself or a loved one, it's essential to consult a healthcare provider for further evaluation and appropriate treatment.

  • Hemangiosarcoma may present with symptoms such as weakness, lethargy, and exercise intolerance due to anemia caused by internal bleeding.
  • Abdominal distension or swelling can occur as the tumor grows and puts pressure on surrounding organs in cases of splenic hemangiosarcoma.
  • Sudden collapse or fainting episodes may occur due to internal hemorrhage and hypovolemic shock in advanced stages of the disease.
  • Pale mucous membranes, such as pale gums, can be a sign of anemia resulting from blood loss associated with hemangiosarcoma.
  • Difficulty breathing or respiratory distress can manifest if the tumor affects the lungs, leading to symptoms such as rapid breathing and coughing.

What Are the Causes of Hemangiosarcoma?

Hemangiosarcoma, a rare and aggressive cancer originating in the blood vessels, has complex and multifactorial causes. While the exact triggers are not fully understood, several risk factors have been identified.

Genetic predisposition plays a significant role, with certain breeds like German Shepherds and Golden Retrievers being more susceptible. Chronic inflammation, exposure to certain chemicals or toxins, and previous radiation therapy are also considered potential contributors to the development of hemangiosarcoma. Additionally, older age and hormonal influences may play a role in the initiation and progression of this malignancy.

  • Genetic predisposition, such as specific breeds like German Shepherds, may increase the risk of developing hemangiosarcoma.
  • Exposure to certain environmental toxins or chemicals, like herbicides or pesticides, could potentially contribute to the development of hemangiosarcoma.
  • Chronic inflammation or long-standing infections may trigger cellular changes that lead to the formation of hemangiosarcoma.
  • Age is a significant factor, with older dogs being more susceptible to developing hemangiosarcoma compared to younger counterparts.
  • Hormonal influences, including reproductive status or hormone imbalances, have been suggested as possible factors in the development of hemangiosarcoma.

When to See a Doctor for Hemangiosarcoma?

Consult a oncologist or surgical oncologist if you notice a persistent lump, unexplained skin lesion, abnormal bleeding, or unexplained weight loss. Early diagnosis and treatment can improve the chances of successful management.

You should see a doctor if you have:

  • A rapidly growing lump or swelling
  • A bruise-like skin lesion that does not heal
  • Persistent pain or unexplained bleeding
  • Unexplained weight loss or ongoing fatigue

Get medical help immediately if:

  • Heavy or uncontrolled bleeding
  • Difficulty breathing or chest pain
  • Sudden severe abdominal pain
  • Loss of consciousness or severe neurological symptoms

These could indicate serious complications requiring emergency medical care.

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How is Hemangiosarcoma Diagnosed?

To diagnose Hemangiosarcoma, a veterinarian typically begins with a thorough physical examination of the patient, followed by blood tests to assess overall health and detect any abnormalities. Imaging studies like X-rays or ultrasounds may be conducted to visualize potential tumors or abnormalities in the body.

A definitive diagnosis often requires a biopsy, where a small sample of tissue is extracted and examined under a microscope by a pathologist. Additionally, in some cases, advanced imaging techniques such as CT scans or MRIs may be employed for further evaluation.

The combination of these diagnostic methods helps in confirming the presence of Hemangiosarcoma and determining the extent of the disease for appropriate treatment planning.

  • Imaging tests like X-rays, ultrasound, and CT scans are used to detect tumors and assess their size.
  • Blood tests may reveal signs of anemia or abnormalities that could indicate the presence of hemangiosarcoma.
  • Biopsy of suspicious tissue is essential for confirming the diagnosis of hemangiosarcoma through microscopic examination.
  • Exploratory surgery may be performed to visualize and obtain tissue samples for definitive diagnosis.
  • Advanced imaging techniques such as MRI may be utilized for better visualization of tumors in certain cases.

What Are the Treatment Options for Hemangiosarcoma?

Hemangiosarcoma treatment options typically involve a multimodal approach tailored to the individual patient. Surgery is often the primary treatment to remove the tumor, followed by chemotherapy to target any remaining cancer cells and prevent recurrence. In some cases, radiation therapy may also be utilized to help control local disease.

Additionally, supportive care such as blood transfusions and medications to manage symptoms like bleeding or organ dysfunction may be necessary to improve the patient's quality of life.

Integrative therapies like herbal supplements or acupuncture benefits could be considered as well to complement conventional treatments and support overall well-being. Regular monitoring and follow-up care are essential to assess treatment response and adjust the management plan accordingly.

  • Surgery is typically the primary treatment for hemangiosarcoma, aiming to remove the tumor and surrounding tissue to prevent further spread. However, due to the nature of this cancer, complete surgical removal may not always be possible.
  • Chemotherapy is commonly used in conjunction with surgery to target any remaining cancer cells and reduce the risk of metastasis. Different chemotherapy drugs may be used depending on the location and extent of the disease.
  • In some cases, radiation therapy may be recommended to target any remaining cancer.

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What are the Risk Factors for Hemangiosarcoma?

While the exact cause of this cancer is not fully understood, several risk factors have been identified. These include breed predisposition, with certain breeds such as German Shepherds, Golden Retrievers, and Boxers being more susceptible.

Age is also a significant risk factor, with older dogs at higher risk. Additionally, factors such as genetics, exposure to certain chemicals, and immune system deficiencies may contribute to the development of hemangiosarcoma. Regular veterinary check-ups and early detection are crucial in managing this aggressive cancer.

  • Breed predisposition, such as German Shepherds, Golden Retrievers, and certain other large breeds, is a significant risk factor for hemangiosarcoma.
  • Age plays a role, with older dogs being more susceptible to developing hemangiosarcoma compared to younger dogs.
  • Gender may influence risk, as female dogs are slightly more prone to hemangiosarcoma than male dogs.
  • Exposure to certain environmental toxins or chemicals could increase the likelihood of developing hemangiosarcoma in dogs.
  • Genetics can contribute to the risk of hemangiosarcoma, with certain genetic factors potentially predisposing dogs to this type of cancer.

What is the Recovery Process for Hemangiosarcoma?

Recovery depends on the stage of the disease and the treatment approach used.

  • Regular monitoring to assess treatment response
  • Follow-up care to detect recurrence
  • Gradual recovery after surgery or therapy
  • Supportive care to improve quality of life
  • Long-term management in advanced cases

Frequently Asked Questions

1. Are there specific signs that indicate Hemangiosarcoma?

Common signs of hemangiosarcoma include weakness, pale gums, enlarged abdomen, and collapsing.

2. How should I care for myself with Hemangiosarcoma and what should I do and avoid?

Follow your treatment plan, attend regular check-ups, follow a healthy diet, avoid smoking and limit alcohol intake.

3. What serious complications could arise from Hemangiosarcoma?

Hemangiosarcoma can lead to internal bleeding, organ damage, and metastasis to other parts of the body, which can be life-threatening.

4. How can Hemangiosarcoma be treated and controlled?

Hemangiosarcoma can be treated with surgery, chemotherapy, and sometimes radiation therapy to help control tumor growth and improve quality of life.

5. Can Hemangiosarcoma return even after successful treatment?

Yes, Hemangiosarcoma can return even after successful treatment due to its aggressive nature and tendency to metastasize.

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