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07-08-2024 Team Medicover general-medicine

Written by Medicover Team and Medically Reviewed by Dr Girish Loya, General Medicine

Vildagliptin 50 mg Uses, Dosage, Side Effects & Precautions

Vildagliptin 50 mg is a commonly prescribed oral medication for managing type 2 diabetes. It helps regulate blood sugar levels by improving insulin function and reducing glucose production. Often used alone or with other anti-diabetic drugs, it is generally well-tolerated with a low risk of weight gain or hypoglycemia.

This article covers its uses, proper dosage, potential side effects, and key precautions you should be aware of before starting treatment.

What is Vildagliptin?

Vildagliptin helps regulate blood sugar levels by increasing the levels of incretin hormones, which stimulate insulin release and reduce the amount of glucose produced by the liver.

Unlike some other diabetes medications, it does not typically cause weight gain or hypoglycemia (low blood sugar) when used alone.

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Vildagliptin 50 mg Uses

Vildagliptin 50 mg is used for:

Management of Type 2 Diabetes Mellitus: Vildagliptin is primarily prescribed to patients with type 2 diabetes who are unable to achieve adequate glycemic control through diet and exercise alone. It can be used as monotherapy or in combination with other anti-diabetic agents.
Improving Glycemic Control: Vildagliptin helps in reducing fasting and postprandial blood glucose levels, thereby improving overall glycemic control.

Vildagliptin 50 mg Dosage

The recommended dosage of Vildagliptin is typically 50 mg once or twice daily. The exact dosage may vary depending on the patient's condition, response to treatment, and other individual factors. It is essential to follow the prescribed dosage and consult a healthcare professional before making any changes.

Vildagliptin Before or After Food

Vildagliptin can be taken with or without food. However, taking it with food may reduce the risk of gastrointestinal side effects. It is essential to follow the specific instructions provided by your healthcare provider regarding the timing of the medication.

How Vildagliptin Works?

Vildagliptin works by:

Inhibiting the DPP-4 enzyme, which breaks down incretin hormones
Enhancing insulin secretion in response to meals
Decreasing excess glucose production by the liver
Improving the overall glycemic control without causing sudden drops in blood sugar

Dosage and Administration of Vildagliptin 50 mg

Vildagliptin 50 mg is typically taken orally, with or without food, depending on the doctor's recommendation. The dosage may vary based on individual needs, medical condition, and other medications being used.

Standard Dosage Guidelines:

Monotherapy (Vildagliptin alone): Usually, 50 mg twice daily (once in the morning and once in the evening).
Combination Therapy: Typically 50 mg once or twice daily, depending on blood sugar control and treatment response.

Important Tips:

Do not exceed a total of 100 mg per day.
Take the tablet at the same time each day to maintain steady blood sugar levels.
If a dose is missed, take it as soon as you remember—unless it's close to the next dose. Do not double up doses.
Follow the prescribed diet and exercise plan alongside medication for best results.
Regular monitoring of blood glucose levels is recommended.

Always follow your healthcare provider's exact instructions, as they may adjust your dose based on your response to treatment or other health conditions.

Potential Side Effects of Vildagliptin 50 mg

Like any medication, Vildagliptin 50 mg can cause side effects. It is essential to be aware of these potential side effects and consult your healthcare provider if you experience any adverse reactions.

Common Side Effects

Some common side effects of Vildagliptin include:

Headache
Dizziness
Nausea
Diarrhea
Nasopharyngitis (inflammation of the nasal passages and throat)

Serious Side Effects

While rare, some severe side effects may occur, including:

Pancreatitis: Severe abdominal pain, nausea, vomiting
Hepatic Dysfunction: Jaundice (yellowing of the skin and eyes), dark urine, fatigue
Hypersensitivity Reactions: Rash, itching, swelling, difficulty breathing

If you experience any of these severe side effects, seek medical attention immediately.

Precautions and Warnings

Before taking Vildagliptin 50 mg, inform your doctor if you:

Have liver or kidney problems
Are pregnant or breastfeeding
Are taking other diabetes medications
Have a history of pancreatitis
Are allergic to vildagliptin or any of its ingredients

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When to See a Doctor?

Consult your doctor if you experience:

Severe stomach pain
Yellowing of skin/eyes (liver issues)
Allergic reactions (swelling, rash, difficulty breathing)
Muscle pain or weakness
Symptoms of low blood sugar (dizziness, sweating, confusion)
Consistently high blood sugar
Before starting new medications or supplements

Regular check-ups are important to monitor your health during treatment.

Conclusion

Vildagliptin 50 mg is an effective and well-tolerated option for managing type 2 diabetes. When combined with a healthy lifestyle and regular monitoring, it can help maintain stable blood sugar levels and reduce the risk of complications. Always take this medication under the supervision of a qualified healthcare professional.

Frequently Asked Questions

Vildagliptin can be used with caution in kidney patients. Dose adjustment may be needed in moderate to severe kidney disease. Always consult a doctor before use.

Yes, vildagliptin helps lower blood sugar in type 2 diabetes by increasing insulin release and reducing glucagon. It's often used alone or with other antidiabetic drugs.

The price of vildagliptin 50 mg in India varies by brand, usually ranging between ₹25 to ₹45 per tablet. It's available under names like Galvus, Jalra, and others.

Metformin reduces glucose production in the liver and improves insulin sensitivity, while vildagliptin boosts insulin release. They're often used together in diabetes treatment.

Glimepiride doesn't directly raise creatinine, but caution is advised in kidney patients. It can increase the risk of low blood sugar if kidney function is impaired.

Vildagliptin is usually taken in the morning and/or evening with or after food. Your doctor may tailor the timing based on your treatment plan and blood sugar levels.

The usual dose is 50 mg once or twice daily, depending on whether it's used alone or with other medicines. Your doctor will decide the correct dosage for you.

Disclaimer:The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.