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13-09-2024 Team Medicover general-medicine

Written by Medicover Team and Medically Reviewed by Dr Mithil B Ghushe, General Medicine

Dizone Tablet Uses Guide

Dizone Tablet is a medicine prescribed for the treatment of chronic alcohol dependence. It works by creating unpleasant effects when alcohol is consumed and helps to reduce cravings and discourage alcohol intake.

This tablet should be used under strict medical supervision as part of a de-addiction program that may include counselling and behavioural therapy.

In this article, we will explore the key uses, dosage, precautions and potential side effects of Dizone Tablet to help you better understand its role in alcohol addiction recovery.

What Are Dizone Tablets?

Dizone Tablets are primarily used to manage and treat alcohol dependence. They contain Disulfiram, an active ingredient that helps deter alcohol consumption by causing unpleasant effects when alcohol is ingested. Available in various dosages like Dizone 250 mg and Dizone 500 mg, these tablets are prescribed by a doctor to help in the recovery process for individuals struggling with alcohol addiction.

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How Does Dizone Work?

Mechanism of Action

Disulfiram, the active component in Dizone Tablets, works by inhibiting the enzyme acetaldehyde dehydrogenase. This enzyme is responsible for metabolising acetaldehyde, a byproduct of alcohol metabolism. When acetaldehyde accumulates in the body, it causes unpleasant symptoms like nausea, vomiting, headache and palpitations. These adverse effects serve as a deterrent and discourage individuals from consuming alcohol.

Pharmacokinetics

When Dizone is taken by mouth, it quickly enters the body through the digestive system. After that, the liver helps break it down. The main way that Dizone leaves the body is through the kidneys. You can expect to feel the effects within about 12 hours after taking it and those effects might last for up to two weeks after your last dose.

Dizone Tablet Uses

Dizone Tablet is commonly used in the medical management of alcohol dependence. It works as a supportive medicine in alcohol addiction therapy, helping patients abstain from alcohol.

Common Uses of Dizone Tablet:

Treatment of chronic alcoholism by creating an aversion to alcohol
Prevention of relapse in individuals recovering from alcohol addiction
Used as part of a proper de-addiction plan including behavioural counselling.
Helps patients stay motivated to avoid alcohol
Used under strict medical supervision due to the risk of severe alcohol reactions.

How to Use Dizone Tablet?

Using Dizone Tablet properly is Important for its effectiveness and safety. It must be taken exactly as prescribed by a doctor.

Guidelines for Use:

Take the tablet as directed by your doctor, usually once or twice a day.
Can be taken with or without food.
Swallow the tablet whole with a glass of water, do not crush or chew.
Strictly avoid alcohol in any form while taking Dizone.
Continue taking the medication for the entire duration prescribed, even if cravings decrease.
Inform your doctor if you experience any side effects or are taking other medications.

Important: Consuming alcohol while on Dizone may lead to serious reactions such as nausea, vomiting, chest pain and low blood pressure. Always consult your doctor before starting or stopping this medicine.

Dizone Tablet Dosage

Dizone 250 mg Tablet

The Dizone 250 mg tablet is prescribed in the starting phase of the treatment. The starting dose ranges from 125 mg to 500 mg daily and is based on the patient's medical history and the intensity of addiction. The dosage may be adjusted based on the patient's response and tolerance to the medicine.

Dizone 500 mg Tablet

500 mg tablets of Dizone may be given to patients who need a stronger dose because lower amounts haven't worked for them. It's very important to follow your doctor's instructions closely and to have regular check-ups to see how well the treatment is working and to watch for any side effects.

Administration Guidelines

Dizone Tablets should be taken orally, with or without food.
It is recommended to take the tablet at the same time each day to maintain consistent blood levels.
Patients should abstain from alcohol consumption for at least 12 hours before starting Dizone and should continue to avoid alcohol for several weeks after discontinuation.

What are the Side Effects of Dizone Tablet?

Common Side Effects

Dizone Tablets are effective in treating alcohol addiction but they may cause several side effects like:

Drowsiness
Fatigue
Headache
Metallic or garlic-like taste.

Severe Side Effects

In rare cases, Dizone can cause severe side effects that require immediate medical attention. These include:

Hepatotoxicity (liver damage)
Peripheral neuropathy (nerve damage)
Psychosis
Severe allergic reactions.

Precautions for Using Dizone Tablet Safely

Dizone Tablet is an effective medicine used in alcohol de-addiction therapy but it must be used carefully. Some safety measures should be followed to avoid serious side effects and ensure the treatment is effective.

Key Precautions to Follow:

Avoid all forms of alcohol: This includes not just drinking alcohol but also avoiding alcohol-based products like mouthwash, cough syrups, perfumes and even food containing alcohol.
Do not self-medicate: Always take Dizone only under medical supervision. Do not increase or decrease the dose without consulting your doctor.
Inform about medical history: Tell your doctor if you have liver problems, heart disease, diabetes, epilepsy or mental health conditions.
Pregnancy and breastfeeding: This medicine is not recommended during pregnancy or breastfeeding unless prescribed by a doctor.
Be aware of side effects: Be alert for symptoms like flushing, nausea, headache, chest pain or dizziness—especially if alcohol is consumed accidentally.
Regular follow-up: Routine medical check-ups and blood tests may be required to monitor your liver function and overall health during treatment.
Do not stop suddenly: Stopping Dizone abruptly may increase the risk of alcohol relapse. Always follow your doctor's instructions when discontinuing the tablet.

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Conclusion

Dizone Tablet can be a helpful part of treatment for alcohol dependence when used correctly and under proper medical supervision. It works by creating an unpleasant reaction to alcohol, which discourages its consumption. However, it's important to strictly avoid alcohol in any form when your are on this medicine, follow the prescribed dosage and attend regular follow-up appointments.

If you have concerns or experience any side effects, don't hesitate to consult your doctor for advice and support.

Frequently Asked Questions

Dizone is prescribed to help individuals overcome alcohol addiction by making drinking an unpleasant experience.

Take Dizone as prescribed by your healthcare provider, usually once daily, depending on your condition.

No, Dizone is not used to manage withdrawal symptoms but to reduce alcohol consumption long-term.

Dizone works for some individuals, but success depends on the person's commitment and monitoring by a doctor.

Dizone works by creating a physical deterrent, whereas other treatments may focus on cravings.

Disclaimer:The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.