Written by Medicover Team and Medically Reviewed by Dr Dileep M, Urology
Disodium Hydrogen Citrate Syrup for Urinary Health
Disodium hydrogen citrate syrup is a commonly prescribed urinary alkalinising agent used to relieve painful urination and manage urinary tract issues and uric acid-related issues like gout and kidney stones.
This reduces urine acidity, relieving irritation and burning sensations. Available in liquid or syrup form, it is an essential component in managing urinary pH balance for various urinary tract conditions.
Formula Used: Disodium Hydrogen Citrate IP 1.25 mg per 5 ml
This syrup is part of a broader category of medicines used for urine acid neutralisation and is considered a reliable solution for acute and chronic urinary concerns.
Disodium Hydrogen Citrate Syrup Uses
Disodium hydrogen citrate syrup has numerous uses, making it suitable for both adults and children. It is often prescribed as part of the treatment options for a urine-related burning sensation.
Common Conditions Treated
- Burning or painful urination (dysuria)
- Urinary tract infections
- Kidney stones (for urinary alkalinization)
- Metabolic acidosis
- Cystitis and other lower urinary tract symptoms
By promoting an alkaline environment in the urinary tract, this syrup helps to reduce inflammation, making it an effective solution for painful urination relief.
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Get Second OpinionHow Disodium Hydrogen Citrate Works?
Disodium Hydrogen Citrate Syrup works by reducing the acidity in urine. It is an alkaliser that helps to ease the burning sensation or discomfort during urination. This medicine neutralises the extra acid in the urine, which is usually caused by urinary tract infections (UTIs) or other urinary problems.
Making the urine more alkaline helps relieve pain, irritation and discomfort during urination. It also helps prevent the formation of some types of kidney stones. This syrup is typically used for short-term relief and should be taken as directed by your doctor.
Disodium Hydrogen Citrate Syrup Dosage
Proper usage is essential for the syrup to be effective and safe.
Usage Tips
- Take after meals to reduce the risk of gastrointestinal discomfort
- Mix it with water or juice if the taste is too strong
- Increase fluid intake to support urinary flushing
Typical Dosage
- Adults: 15–30 ml per day in divided doses.
- Children: 5–15 ml per day (doctor's guidance required).
- Pregnancy: Only under strict medical advice.
Its effectiveness increases when supported with lifestyle changes and dietary care.
In case of emergency or severe urinary symptoms, you may visit our Medicover Hospitals immediately.
How to Take Disodium Hydrogen Citrate
Disodium Hydrogen Citrate is taken as an oral syrup to make urine less acidic and relieve problems such as burning urination, kidney stones, or gout.
- Dilution: Always dilute the syrup with a glass of water before taking it.
- Dosage: Adults are usually advised 15-30 ml per day in divided doses, or as directed by the
doctor.
- Timing: Take it after meals to avoid stomach upset.
- Shake well before use to ensure the medicine is properly mixed.
- Do not self-medicate: The exact dose and duration depend on your condition and should be followed as per your doctor's advice.
Benefits of Disodium Hydrogen Citrate Syrup
The benefits of disodium hydrogen citrate syrup go beyond symptom relief. It offers huge relief to urinary health when combined with a healthy fluid intake and other therapeutic options.
Key Benefits Include
- Prevents the formation of uric acid stones
- Reduces acidity that causes bladder discomfort
- Supports medications used for bladder inflammation
- Provides fast and lasting relief from burning sensations during urination
- Improves antibiotic absorption during UTI treatment
- Alkalizes urine gently without harsh side effects
- Can be used alongside other alkalinising syrups for urinary health support
Patients with chronic conditions like cystitis, gout or uric acid imbalances often benefit from its use.
Disodium Hydrogen Citrate Syrup Side Effects
Most people tolerate this syrup well when taken as directed, but some may experience mild to moderate side effects.
Possible side effects include:
- Stomach upset or mild abdominal pain
- Nausea or vomiting
- Frequent urination (as the urine becomes more alkaline)
- Diarrhea or loose stools
- Flatulence or gas
Rare but serious:
- Allergic reactions like rash, itching or breathing difficulty
- Worsening kidney issues if taken without medical supervision
If things don’t improve or get worse, it’s best to consult our Urologist.
Precautions for Safer Use of Disodium Hydrogen Citrate Syrup
Disodium hydrogen citrate is generally safe when taken under medical supervision, but there are important precautions to be aware of to avoid unwanted side effects or reduced effectiveness.
- Use under medical advice only: Especially in children, elderly, and people with underlying health conditions.
- Kidney health monitoring: People with any form of kidney disorder should use this syrup cautiously, as it can alter electrolyte balance.
- Monitor salt intake: Since the syrup contains sodium, it should be avoided or used cautiously in people on a low-sodium diet or with conditions like hypertension, heart disease, or fluid retention.
- Hydration is key: Drink plenty of water while using this medication to flush out the urinary tract and prevent stone formation.
- Pregnancy and breastfeeding: Use only if prescribed by a doctor. Safety data is limited, so benefits should outweigh the risks.
Food and Drink to Avoid:
- Caffeinated drinks like coffee and energy drinks
- Citrus fruits and juices (orange, lemon)
- Spicy or heavily salted foods
- Alcohol
Recommended:
- Drink 8-10 glasses of water daily
- Eat alkaline-promoting foods like cucumber and leafy greens
- Opt for low-sodium meals
Combining proper medication usage with dietary awareness strengthens the effects of this urinary alkalizer.
Medicines to Avoid with Disodium Hydrogen Citrate Syrup
Here are some medicines that you must avoid while taking disodium hydrogen citrate syrup:
- Antacids with aluminium or Magnesium: These can disrupt your body's natural balance and cause problems.
- Potassium-sparing diuretics: These can raise your potassium levels too high, which is unsafe.
- Tetracycline & Nitrofurantoin: These medicines may not work as well when taken with disodium hydrogen citrate syrup.
- Aspirin and salicylates: These can affect how your body gets rid of certain drugs, making them less effective.
- Lithium: This medication, used for mood stabilisation, may become too strong or not work properly.
- Methenamine: This medicine will not work effectively if your urine becomes too alkaline due to the syrup.
Contraindications of Disodium Hydrogen Citrate
Disodium hydrogen citrate syrup should not be used in certain health conditions due to the risk of complications. It's important to consult a healthcare provider before using this medication, especially if you have any of the following issues:
- People with severe kidney disease
- Patients with heart failure or high blood pressure
- Those on a low-sodium diet
- People with urinary tract obstruction
- Patients with metabolic or respiratory alkalosis
- Known hypersensitivity or allergy to citrate compounds
Caution: Always inform your doctor about your full medical history and any medications you're taking before using disodium hydrogen citrate syrup.
Comparing Disodium Hydrogen Citrate Syrup vs Liquid Forms
While both terms are often used interchangeably, the format can influence patient preference and tolerability.
- Syrup: Usually flavoured, easier for children or the elderly to take
- Liquid: Slightly less viscous but similar in composition and function
Both serve the same therapeutic purpose and have similar dosage instructions. Choosing between the two often depends on taste preference and ease of swallowing.
Expert Advice and Safety Tips
- Disodium Hydrogen Citrate should be taken after meals with a full glass of water or fruit juice to avoid stomach discomfort.
- Make sure to continue the medicine as advised by your doctor for the best results.
- Some people may get stomach pain while taking it if it becomes too bothersome; do let your doctor know.
- Also, inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
Expert guidance ensures better outcomes and minimizes the risk of misuse.
Doctor Recommendations
- Do not take for more than 5-7 days without consultation
- Avoid if you have chronic kidney disease unless cleared by a doctor
- Keep it out of reach of children
- Store at room temperature away from light and moisture
- Monitor for any signs of bloating or diarrhea
Storage Instructions
- Store at room temperature (below 25°C).
- Keep the bottle tightly closed and away from direct sunlight and moisture.
- Do not freeze the syrup.
- Keep out of reach of children and pets.
- Do not use it after the expiration date mentioned on the label.
Disodium Hydrogen Citrate Syrup in Pregnancy
Disodium Hydrogen Citrate Syrup is mainly used as a urinary alkalizer for conditions like kidney stones or urinary tract infections. During pregnancy, it should be taken only if prescribed by a doctor. The safety of this medicine in pregnant women has not been fully established, and improper use may affect both the mother and the baby.
If your doctor recommends it, the dosage will be carefully adjusted based on your health condition. Do not self-medicate during pregnancy. Always consult your gynecologist or healthcare provider before using this syrup.
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Schedule Your AppointmentDisodium Hydrogen Citrate Syrup Price in India
Disodium Hydrogen Citrate Syrup is an effective urinary alkalizer commonly prescribed for conditions such as kidney stones, urinary tract infections, and gout. In India, the syrup is generally available in 100 ml bottles, and the price usually falls in the range of ₹80 to ₹120, depending on the manufacturer, brand, and pharmacy location. Being an affordable medicine, it is easily accessible across most medical stores.
Conclusion:
Disodium hydrogen citrate syrup offers a safe, effective, and fast-acting solution for many urinary discomforts. Whether you are managing UTIs, dealing with kidney stones, or seeking relief from acidity-related pain, this syrup can help restore comfort and balance.
Its compatibility with other therapies and ease of use make it a trusted option across age groups. When used correctly and with a healthy routine, it plays an important role in maintaining urinary health.
If you're facing recurring burning sensations, discomfort while urinating, or dealing with acidic urine, speak to a healthcare provider about incorporating disodium hydrogen citrate syrup into your treatment plan.
Frequently Asked Questions
Disodium Hydrogen Citrate Syrup should only be used during pregnancy if prescribed by a doctor. It's important to consult with a healthcare provider to ensure safety and proper dosage adjustments during pregnancy.
Yes, Disodium Hydrogen Citrate Syrup can be used for children under medical supervision. The dosage will be adjusted based on the child's age and health condition to ensure safe and effective treatment.
For best results, Disodium Hydrogen Citrate Syrup should be taken after meals to reduce the risk of stomach upset. Follow your doctor’s instructions on dosage timing for optimal relief and effectiveness.
Use with caution during pregnancy and breastfeeding. Always consult a doctor before use, as safety data is limited and high doses may pose risks to mother or baby.
Yes. People with kidney disease, heart problems, high blood pressure, or electrolyte imbalance should use it carefully. Medical supervision is advised.
Follow the prescribed dose strictly. Drink plenty of water, and avoid long-term use without medical advice. Do not use it if you are on a low-sodium diet unless approved by a doctor.
Disodium Hydrogen Citrate solution works as a urinary alkalizer, reducing the acidity of urine. It helps relieve discomfort caused by urinary tract infections, kidney stones, or gout. By making urine less acidic, it also helps prevent certain types of kidney stones from forming.
Shake the bottle well before use and measure the prescribed dose. It is best to dilute the syrup in a glass of water and take it after meals. Always follow your doctor's instructions for the correct dose and duration.
No, Disodium Hydrogen Citrate is not habit-forming. It works by making urine less acidic and does not affect the brain or cause dependency. You can use it safely as prescribed by your doctor.
You should not stop the syrup without consulting your doctor, even if symptoms improve. Stopping early may reduce its effectiveness and your condition might return. Always follow the prescribed duration.
If you miss a dose, take it as soon as you remember. If it's almost time for the next dose, skip the missed one and continue the regular schedule. Do not double the dose to make up for a missed one.
It is better to avoid alcohol while taking Disodium Hydrogen Citrate. Alcohol can irritate the stomach and reduce the effectiveness of the syrup. Always follow your doctor's advice regarding diet and drinks.
Disclaimer:The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.

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