Written by Medicover Team and Medically Reviewed by Dr Swapnil Sanjay Kakad

Proper Deriphyllin Tablet Dosage for Adults Explained

Deriphyllin tablets are commonly prescribed for respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). Understanding the appropriate dosage guidelines for Deriphyllin tablets is crucial for achieving optimal therapeutic outcomes while minimizing potential side effects.

This article delves into the specifics of Deriphyllin tablet dosage, mainly focusing on the 150 mg and 300 mg variants, including Deriphyllin Retard 150 tablets.

What is Deriphyllin?

Deriphyllin is a combination medication containing two active ingredients: theophylline and Etophylline . Theophylline is a bronchodilator that helps relax the muscles in the lungs and chest, making it easier to breathe. Etophylline increases the bronchodilator effect of theophylline, providing a synergistic benefit for patients with respiratory conditions.

Deriphyllin Tablet Dosage for Adults

Standard Dosage Guidelines

The standard dosage of Deriphyllin tablets for adults can vary based on several factors, including the severity of the condition, the patient's weight, age, and overall health. For adults, the general dosage recommendation is:

However, these are general guidelines, and a healthcare professional should always determine the exact dosage.

Adjustments Based on Specific Conditions

In some cases, the dosage of Deriphyllin may need to be adjusted based on specific conditions or patient responses. For instance:

Monitoring and Adjustments

Regular monitoring of blood theophylline levels is often recommended to ensure therapeutic efficacy and avoid toxicity. The therapeutic range for theophylline is generally between 10 and 20 mcg/mL. Levels above this range can lead to toxicity, while levels below may not provide adequate symptom relief.

Deriphyllin 150 mg Dosage

Deriphyllin 150 mg is one of the most prescribed strengths for adults. It is generally taken once or twice a day, preferably after food to reduce gastric discomfort.

Your doctor may increase the dose to 300 mg/day depending on symptom control and tolerance. Those with liver or kidney dysfunction may require lower doses to avoid drug accumulation and toxicity.

Deriphyllin Dosage Frequency

The frequency of Deriphyllin dosage depends on the tablet's formulation (immediate-release or sustained-release).

Make sure to take the tablet at the same time every day for consistent therapeutic effect. Do not crush or chew sustained-release tablets unless advised.

Deriphyllin Uses and Benefits

Deriphyllin is primarily used to manage respiratory diseases that cause bronchospasm or difficulty in breathing. Below are its key uses and therapeutic advantages:

Uses:

Benefits:

Deriphyllin Retard 150 Tablet

Deriphyllin Retard 150 tablets are a sustained-release formulation designed to provide a prolonged effect, reducing the need for frequent dosing. The dosage guidelines for Deriphyllin Retard 150 tablets are:

Sustained-release formulations like Deriphyllin Retard 150 are particularly beneficial for patients requiring consistent plasma drug levels over an extended period.

Factors Influencing Deriphyllin Dosage

Several factors can influence the appropriate dosage of Deriphyllin tablets, including:

Patient Weight

The dosage of Deriphyllin is often calculated based on the patient's weight. Heavier individuals may require a higher dose to achieve the desired therapeutic effect.

Age

Elderly patients may be more susceptible to the side effects of Deriphyllin, necessitating a lower starting dose and careful monitoring.

Liver Function

Since theophylline is metabolized in the liver, patients with impaired liver function may require a lower dose to avoid toxicity.

Concurrent Medications

Certain medications can interact with theophylline, affecting its metabolism and plasma levels. For instance, drugs like cimetidine and fluoroquinolones can increase theophylline levels, necessitating a lower dose of Deriphyllin.

Smoking

Smoking can induce the metabolism of theophylline, reducing its plasma levels and potentially requiring a higher dose of Deriphyllin.

Deriphyllin Side Effects in Adults

Although Deriphyllin is generally well-tolerated, it can cause side effects in some individuals, particularly if taken in high doses or combined with other stimulants.

Common Side Effects:

Serious Side Effects (Seek medical attention):

Most side effects subside as the body adjusts, but any persistent or severe symptoms should be reported immediately to a doctor.

Precautions

To minimize the risk of side effects, it is essential to:

Conclusion

Understanding the dosage guidelines for Deriphyllin tablets is essential for the effective management of respiratory conditions such as asthma and COPD. The dosage must be tailored to the individual patient based on factors such as weight, age, liver function, and concurrent medications. Regular monitoring and consultation with a healthcare professional are crucial to achieving optimal therapeutic outcomes while minimizing potential side effects.

Frequently Asked Questions