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Vildagliptin

vildagliptin

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By Medicover Hospitals / 11 Mar 2021
Home | Medicine | Vildagliptin

What is Vildagliptin?

  • Vildagliptin is a new oral anti-hyperglycemic (anti-diabetic) medication from the new dipeptidyl peptidase-4 (DPP-4) inhibitor class. The medication works by preventing DPP-4 from inactivating glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP). This inhibitory activity leads to a two-fold action in the pancreas' islets of Langerhans, where GLP-1 and GIP potentiate insulin secretion by beta cells while suppressing glucagon secretion by alpha cells.
    1. Vildagliptin Uses
    2. Vildagliptin Side effects
    3. Precautions
    4. Overdose
    5. Warnings
    6. Storage
    7. Vildagliptin vs Sitagliptin
    8. Frequently Asked Questions
    9. Citations

    Vildagliptin Uses:

  • The medication is used for the treatment of Type 2 diabetes mellitus. This is used along with diet and exercise to improve blood sugar control in adults with Type 2 diabetes. The medication is a type of anti-diabetic drug. It works by causing the pancreas to release more insulin and decreasing the hormones that cause blood sugar levels to rise. Fasting and post-meal sugar levels are reduced as a result of this.
  • Vildagliptin Side Effects:

  • Some of the common and major side effects of Vildagliptin are:
    • Headache
    • Cough
    • Constipation
    • Sweating
    • Hypoglycaemia
    • Weakness
    • Excessive sweating
    • Heartburn
    • Swelling of face, lips and eyelids
  • The common side effects don’t need any medical attention and will disappear as your body gets adjusted to the dosage. But if you are facing any kind of serious or rare side effects then immediately seek medical attention.
  • Precautions:

  • Before using Vildagliptin talk with your doctor if you are allergic to it or any other medications. The product can contain some inactive ingredients which will cause serious allergic reactions or other serious problems. If you are having any of the following medical histories then talk with your doctor immediately, such as skin allergy, Type I diabetes mellitus, Diabetic Ketoacidosis and Hepatic Impairments.
  • How to use Vildagliptin?:

    • Read the manufacturer's printed information carefully to know about the procedure. It will provide you with more detail about vildagliptin tablets as well as a complete list of the possible side effects that you can encounter as a result of taking them.
    • Take vildagliptin exactly as directed by the doctor. The normal dosage is one 50 mg tablet taken twice a day, but depending on your other medications, you might only need one dose per day. Your doctor will instruct you exactly how many doses to take, and this detail will be printed on the label of the tablet pack to act as a reminder.

    Missed Dose:

  • As soon as you remember, take the missing dose. If it’s time for the next dose, skip the missed dose. Do not take a double dose to compensate for a missed dose.
  • Overdose:

  • Overdose of this medication can lead to some serious side effects like irregular heartbeat, trouble while breathing, severe dizziness and fainting.
  • Warnings for serious Health Conditions:

  • Pregnancy:
  • Pregnant women should avoid taking this drug unless it is absolutely appropriate. Before taking this drug, talk to your doctor about all the complications and benefits. Depending on your health condition, your doctor can recommend a safer alternative.
  • Breastfeeding:
  • The medication can pass into the breast milk and can cause some serious side effects to the infants. Avoid taking this medication without consulting your doctor while you are breastfeeding.
  • Storage:

  • Direct contact with heat, air and light may damage your medicines. Exposure to medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach. Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).
  • Vildagliptin vs Sitagliptin:

    Vildagliptin
    Sitagliptin
    Vildagliptin is a new oral anti-hyperglycemic (anti-diabetic) medication from the new dipeptidyl peptidase-4 (DPP-4) inhibitor class. Sitagliptin is a prescription drug and it is available in the form of an oral tablet.
    The medication is used for the treatment of Type 2 diabetes mellitus. This is used along with diet and exercise to improve blood sugar control in adults with Type 2 diabetes. Sitagliptin tablets can be taken with a proper diet, exercise, and other medication for controlling high blood sugar. The medication is used in people with type 2 diabetes.
    Some of the common and major side effects of Vildagliptin are:
    • Headache
    • Common cold
    • Cough
    • Constipation
    • Dizziness
    Some of the common side effects of Sitagliptin are:
    • Stomach cramp
    • Diarrhea
    • Respiratory infection
    • Headache

    Frequently Asked Questions:

    The medication is used for the treatment of Type 2 diabetes mellitus. This is used along with diet and exercise to improve blood sugar control in adults with Type 2 diabetes. The medication is a type of anti-diabetic drug.
    Vildagliptin is an important and well-tolerated treatment choice for elderly patients with type 2 diabetes, showing comparable glycemic regulation to metformin but having better GI tolerability.
    Vildagliptin has been shown to be reasonably safe in clinical trials; however, long-term safety evaluations and clinical experience with the effects of DPP4 inhibition are needed. The DPP4 enzyme is found in a variety of tissues and is a substrate for a variety of hormones and peptides in the human body.
    If you've been prescribed vildagliptin, take it first thing in the morning. Take the first dose in the morning and the second dose in the evening if you've been advised to take two doses every day. Vildagliptin tablets may be taken before, during, or after meals.
    Vildagliptin, the active ingredient in Galvus, is a dipeptidyl-peptidase-4 (DPP-4) inhibitor. It functions by stopping the body from breaking down 'incretin' hormones. Following a meal, these hormones are released, stimulating the pancreas to produce insulin.
    Some of the common and major side effects of Vildagliptin are:
    • Headache
    • Common cold
    • Cough
    • Constipation
    • Dizziness

    Citations:

  • Vildagliptin, https://link.springer.com/article/10.2165/11206370-000000000-00000://link.springer.com/article/10.2165/11209910-000000000-00000
  • Effects of Vildagliptin, https://care.diabetesjournals.org/content/30/4/890.short