Teneligliptin tablet is an oral antidiabetic medication used to manage type 2 diabetes mellitus. It belongs to the class of Dipeptidyl Peptidase-4 (DPP-4) inhibitors, also known as gliptins. It is commonly used in combination with diet and exercise to improve blood sugar control in adults with type 2 diabetes.
What is Teneligliptin Tablet?
Teneligliptin tablet is a DPP-4 inhibitor that works by regulating insulin levels after meals and reducing glucose production by the liver. It is typically prescribed when lifestyle changes and other medications do not sufficiently control blood glucose levels.
What are the Uses of Teneligliptin Tablets?
Teneligliptin tablet is mainly used for the treatment of type 2 diabetes mellitus. It helps regulate blood sugar levels in adults by enhancing insulin secretion and suppressing excess glucose production by the liver. It can be prescribed alone or in combination with other antidiabetic medications to improve long-term glycemic control and reduce the risk of diabetes-related complications.
Conditions Teneligliptin Treats
Type 2 Diabetes Mellitus: Helps control high blood sugar levels and prevents complications such as nerve damage, kidney issues, and blindness.
Insulin Resistance: Improves the body's response to insulin, helping regulate glucose levels more effectively.
Postprandial Hyperglycemia: Reduces spikes in blood sugar after meals by enhancing insulin secretion.
Early-Stage Diabetes: Used to manage glucose levels in newly diagnosed type 2 diabetes patients who are not yet on insulin.
Combination Therapy: Often prescribed along with other antidiabetic medications like metformin for better glycemic control.
Secondary Uses of Teneligliptin
May be used in combination with other antidiabetic medications like metformin, sulfonylureas, or insulin to enhance glycemic control.
Sometimes prescribed for patients who do not respond well to monotherapy.
It can help improve postprandial blood glucose levels when added to existing diabetes treatment.
It may be beneficial in patients with mild to moderate renal impairment, under medical supervision.
Often considered in dual or triple therapy regimens for better long-term glucose management.
How Does Teneligliptin Tablet Work?
Teneligliptin tablet works by inhibiting the enzyme DPP-4 (dipeptidyl peptidase-4), which is responsible for breaking down incretin hormones in the body. Incretins help increase insulin release and decrease glucagon levels, especially after meals. By prolonging the action of these hormones, Teneligliptin improves blood sugar control in people with type 2 diabetes. It helps reduce both fasting and post-meal glucose levels. This medication is usually part of a broader diabetes management plan that includes diet and exercise. Teneligliptin works by inhibiting the DPP-4 enzyme, which increases the levels of incretin hormones. These hormones help:
Increase insulin release from the pancreas.
Decrease glucagon (a hormone that raises blood sugar) levels
This dual action helps lower blood glucose levels, especially after meals.
Teneligliptin Tablet Dosage
The typical adult dose of Teneligliptin is 20 mg once daily, with or without food. Depending on the patient's response and the doctor's recommendation, the dose may be increased to 40 mg daily. Dosage adjustments are generally not needed for patients with kidney issues, but medical supervision is advised. Always follow the dosage prescribed by your doctor.
Typical Adult Dose: 20 mg once daily. In some cases, the dose may be increased to 40 mg daily if necessary.
Can be taken with or without food.
No dosage adjustment is required in patients with renal impairment.
What Should I Do If I Miss a Dose?
Take the missed dose as soon as you remember.
If it's almost time for your next scheduled dose, skip the missed one.
Do not take two doses at the same time to make up for the missed dose.
Resume your regular dosing schedule.
Consult your doctor if you frequently forget to take your medicine.
What Happens If an Overdose?
Symptoms of Overdose:
Severe hypoglycemia (especially if taken with other antidiabetics)
Dizziness, sweating, confusion, rapid heartbeat
Confusion or blurred vision
Fatigue or weakness
Nausea or vomiting in some cases
Consult your healthcare doctor before taking medication in case of suspected overdose; call emergency medical services immediately.
Get a second opinion from trusted experts and makeconfident, informed decisions.
What are the Side Effects of Teneligliptin Tablets?
Common side effects of Teneligliptin include headache, constipation, upper respiratory tract infection, fatigue, and gastrointestinal discomfort. In some cases, it may cause hypoglycemia when used with other diabetic medications. Though rare, allergic skin reactions and kidney issues can also occur. Seek medical advice if any symptoms become severe or unusual.
Hypoglycemia (low blood sugar, especially when combined with other antidiabetics)
Skin reactions (rash, itching)
Kidney-related issues
Important Precautions and Warnings for Teneligliptin Tablets
Before using Teneligliptin, inform your doctor if you have a history of liver disease, kidney disease, heart problems, or QT prolongation. It should be used with caution in individuals with severe hepatic impairment. Teneligliptin is not recommended during pregnancy or breastfeeding unless explicitly advised by a healthcare provider. Always disclose your full medical history and current medications to avoid complications.
Who Should Avoid Teneligliptin
Individuals with known allergy to Teneligliptin
Patients with severe hepatic impairment (only taken under strict medical supervision)
Individuals with a history of pancreatitis should use it cautiously and under supervision.
Pregnant or breastfeeding women, unless specifically prescribed by a healthcare provider
Children or adolescents, as safety and efficacy, are not well established in these groups.
Elderly patients or those with multiple comorbidities
Use of other medications that lower blood sugar (risk of hypoglycemia)
Are There Any Age Restrictions?
Teneligliptin tablet is generally prescribed for adults with type 2 diabetes and is not recommended for use in children or adolescents under 18 years of age due to limited safety and efficacy data. Elderly patients can take the medication but may require closer monitoring for kidney function and possible side effects. Always consult your doctor before starting Teneligliptin to ensure it's appropriate for your age and overall health condition.
Alcohol or Food Interactions
Alcohol or certain foods may affect how the Teneligliptin tablet works in the body. Drinking alcohol while taking this medication can increase the risk of low blood sugar (hypoglycemia), especially if combined with other antidiabetic drugs. It's best to limit alcohol intake and follow a balanced diet as advised by your doctor. Always inform your healthcare provider about your dietary habits while using the Teneligliptin tablet for safe and effective treatment.
Possible Interactions with Other Medications (Drug Interactions)
Teneligliptin tablets may interact with other antidiabetic medications, which can increase the risk of low blood sugar (hypoglycemia). Caution is advised when used with insulin, sulfonylureas, or other drugs that affect glucose levels. Additionally, certain antibiotics, antifungals, and cardiovascular medicines may alter how Teneligliptin works. Always inform your doctor about all medicines, supplements, or herbal products you are taking to avoid unwanted drug interactions.
How Should Teneligliptin Tablets Be Stored?
Store Teneligliptin at room temperature (20°C to 25°C / 68°F to 77°F) in a cool, dry place, away from direct sunlight, heat, and moisture. Keep it in its original packaging and out of reach of children and pets. Improper storage can affect the medicine's effectiveness and safety.
Recommended Storage Temperature
Store at room temperature between 68°F and 77°F (20°C and 25°C).
Keep the medicine in a cool, dry place away from moisture and heat.
Avoid storing in bathrooms or near sinks.
Protect from direct sunlight and extreme temperatures.
Do not freeze the medicine.
Keep it in the original packaging.
Store out of reach of children and pets.
Follow any specific storage instructions on the label.
What Happens If Teneligliptin Is Not Stored Properly?
Exposure to heat, light, or moisture may degrade the drug's effectiveness.
Always keep the medicine tightly closed, away from children and pets.
Expired tablets may not show visible changes but may not work
Contamination if exposed to air, humidity, or improper containers
Teneligliptin vs Sitagliptin
Teneligliptin
Sitagliptin
Teneligliptin is a popular drug used for the treatment of type 2 diabetes mellitus.
Sitagliptin is a prescription oral tablet available under the brand name Januvia, used for managing type 2 diabetes.
It helps manage blood glucose levels by regulating insulin secretion and reducing glucose production in the liver.
Sitagliptin is used alongside diet, exercise, and sometimes other medications to control high blood sugar in type 2 diabetes patients.
Teneligliptin is used to treat type 2 diabetes mellitus by improving blood sugar control.
Teneligliptin is typically taken once daily, with or without food. The best time to take it can vary based on individual preference and doctor's recommendation.
Teneligliptin is generally considered safe for kidneys. However, it is important to monitor kidney function regularly while using this medication, especially in patients with pre-existing kidney disease.
Teneligliptin and metformin are different types of diabetes medications. The choice between them depends on individual factors such as the patient's response to treatment, medical history, and potential side effects.
Teneligliptin is generally considered safe for the heart. It does not typically cause significant cardiovascular side effects. However, always consult with a healthcare provider to discuss any specific concerns.
Teneligliptin is considered safe for the liver. It is metabolized in the liver, but it does not usually cause liver problems. Regular liver function tests may be recommended during treatment.
Teneligliptin has a duration of action of approximately 24 hours, which allows for once-daily dosing.
Teneligliptin is not known to increase blood pressure as a direct effect. However, individual responses to medications can vary, so monitoring blood pressure during treatment is recommended.
Teneligliptin should not be stopped without consulting a healthcare provider. Abruptly stopping diabetes medications can lead to uncontrolled blood sugar levels. Your doctor will guide you on when and how to adjust or discontinue the medication if necessary.
Teneligliptin tablets are primarily used to treat type 2 diabetes mellitus to help lower blood sugar levels.
Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.
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