What is Nadifloxacin?
Nadifloxacin is a broad-spectrum quinolone antibiotic that has been approved for use in the treatment of acne vulgaris and skin infections. Since antibiotic exposure causes drug resistance in pathogenic and colonising bacteria, it is not required to use an antibiotic that belongs to the class of agents which is widely used systemically for treating a wide variety of infections. Mainly, the drug is potential to be used as a short treatment of skin infections.
Nadifloxacin Uses
This antibiotic is a fluoroquinolone. Nadifloxacin is used for the treatment of bacterial infections. It's used to treat stuff like acne and infections on the skin. It functions by inhibiting the activity of DNA-gyrase, a bacterial enzyme. This prohibits bacterial cells from dividing and repairing, resulting in their death.
It is an antibiotic that prevents infection-causing bacteria from growing on the skin. It prevents the synthesis of essential proteins needed for bacterial survival. It helps to treat skin infections including boils, impetigo, and infected hair follicles. It may also be used to treat infections in minor skin cuts or wounds.
Nadifloxacin Side Effects
Some of the common & major side effects of Nadifloxacin are:
- Burning Sensation
- Twitching
- Flushes
- Papule
- Irritation
- Dryness of skin
- Irritation
- Itching
- Redness
- Skin blistering
- Increased sweating
While a person is under the treatment of this drug they might experience certain side effects that may not be adverse. But if your reactions persist or worsen over time then contact your doctor immediately.
Precautions
Before using Nadifloxacin, talk with your doctor if you are allergic to it or any other medications related to it. The medication may contain inactive ingredients which will cause serious allergic reactions to your skin. Before using the medication talk to your doctor if you have any medical history such as a burning sensation, itching or allergy to any appointment.
How to use Nadifloxacin?
This medication can only be used on the upper layer of the skin that is only on the external level. Apply the cream after washing and drying the affected area. If your hands are the affected region, wash your hands after applying. NADIBACT cream/gel is used to treat acne vulgaris and other skin infections caused by bacteria. It should be applied twice daily to the lesions. It can be used after washing the face if you have acne.
Missed Dose
Apply the Cream as soon as you remember if you miss applying it. However, if its time for your next application of the cream/gel then apply it only once and return it to your daily schedule. Do not apply excessive cream to the affected area.
Overdose
An overdose of this drug is unlikely to result in significant side effects. However, ingestion of this medicine may result in injury, necessitating immediate medical attention.
Warnings for some Serious Health Conditions
Allergic Reaction
Some patients can experience allergic reactions as a result of taking this medication. Symptoms such as trouble breathing or swallowing, chest tightness, swelling, skin rashes, hives, and others should be reported to the doctor right away. Depending on the patient's clinical condition, effective corrective steps, dosage changes, or replacement with a suitable alternative may be needed.
Pregnancy
Pregnant women can use this drug by following major precautions. Before taking this drug, speak to your doctor about all of the complications and benefits.
Breastfeeding
Unless absolutely appropriate, this medication should not be used by a breastfeeding mother. Before using this drug, talk to your doctor about all of the potential complications and benefits. If the medication is used, extra measures should be taken to ensure that the child is not exposed to it. Avoid applying Nadifloxacin cream/ gel near the breast as the baby may get into contradiction with the drug.
Storage
Direct contact with heat, air and light may damage your medicines. Exposure to medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach.
Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).
Nadifloxacin vs Mupirocin
Nadifloxacin |
Mupirocin |
|---|---|
| Nadifloxacin is a broad-spectrum quinolone antibiotic that has been approved for use in the treatment of acne vulgaris and skin infections. | Mupirocin is an antibiotic which helps to prevent bacteria from growing on your skin. It comes in various forms such as topical ointment, topical cream and nasal ointment. |
| It helps to treat skin infections including boils, impetigo, and infected hair follicles. It may also be used to treat infections in minor skin cuts or wounds. | Mupirocin is a drug used for the treatment of impetigo and infections which is caused by staphylococcus aureus and beta-hemolytic streptococcus. |
Some of the common & major side effects of Nadifloxacin are:
|
Most serious side effects of Mupirocin are:
|
Citations
Relationship between mutations in the DNA gyrase and topoisomerase IV genes and nadifloxacin resistance in clinically isolated quinolone-resistant Staphylococcus aureusNadifloxacin, an antiacne quinolone antimicrobial, inhibits the production of proinflammatory cytokines by human peripheral blood mononuclear cells and normal human keratinocytes
