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Griseofulvin

griseofulvin

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By Medicover Hospitals / 29 Nov 2020
Home | Medicine | Griseofulvin

What is griseofulvin?

Griseofulvin oral tablet is a prescription medicine that is available as a Gris-PEG brand name drug. It's available as a generic drug. Generic medications typically cost less than a version of the brand name. In certain cases, they may not be available as a brand-name drug in all strengths or forms.

  • Griseofulvin comes as an oral suspension of liquid as well.
  • Griseofulvin oral tablet is available as both; generic and brand-name drugs.
  • Brand name: -Gris-PEG.
  • Griseofulvin also comes in liquid suspension you can take it by mouth.
  1. Griseofulvin uses
  2. Griseofulvin side effects
  3. Interactions
  4. Griseofulvin Warnings
  5. Overdose
  6. Griseofulvin vs Itraconazole
  7. Frequently Asked Questions
  8. Citations

Why is it used?

  • The oral tablet of Griseofulvin is used to treat fungal infections that can affect various parts of your body. Your hair, nails, and skin contain these.

  • How does it work?

    Griseofulvin is in a class of medicines called antifungal agents. A community of medicines that function in a similar way is a class of drugs. For the treatment of related conditions, these medicines are also used.

    This medicine works by binding to a portion of the fungus in your body that triggers the infection. This avoids the multiplication of the fungus. This medicine also stops the spread of the fungus to new cells. Such practices cause the infection to die off.


    Griseofulvin Side Effects:

    The oral tablet of Griseofulvin does not induce drowsiness. It can cause you other side effects, however. more widespread side effects

  • More frequent side effects of griseofulvin may include the following:
    • Rash
    • Numbness or tingling
    • Infections of yeast in your mouth
    • Pain in the stomach
    • Diarrhea Infection
    • Heartburning
    • Nausea and sickness
    • By vomiting
    • Dizziness, vertigo
    • Headaches
    • Sleeping Trouble
    • Uncertainty

    They can go away within a few days or a couple of weeks if these effects are mild.

  • Significant adverse reactions
  • If you have severe side effects, call your doctor right away. If your symptoms appear to be life-threatening, or if you think you have a medical emergency, call 911. The following may contain severe side effects and their symptoms:

    • Extreme allergic reaction to the eyes. Symptoms might include:
    • Swelling of your tongue or face
    • The Hives
    • Blisters or peeling skin
    • With fever
    • Damages to the liver. Symptoms might include:
    • Easier than usual bruising than normal bruising
    • Tiredness
    • Skin Yellowing or the whitening of your eyes
    • Stomach pain
    • Weakness
    • Loss of appetite

    Important Information

    Severe skin reactions Warning: Skin reactions may be caused by this drug. This can be life-threatening and serious. Hives, fever, swelling of the tongue and ears, and peeling or blistering of the skin may be symptoms. Stop taking the medication and call your doctor right away if you have signs of a skin reaction.

  • Liver damage warning: Severe liver damage can be caused by this drug. This effect is more likely if you use the medication for long periods of time or at high doses. Symptoms may include easily occurring bruising, exhaustion, weakness, pain in the stomach, loss of appetite, and yellowing of the skin or the whites of your eyes.

  • Pregnancy warning: During pregnancy, you should not take this drug. In females who took this drug during pregnancy, there have been two cases of conjoined twins. During treatment with this medicine, women can use reliable birth control. During therapy and for 6 months after leaving treatment, men should use birth control.

  • Interactions

    Griseofulvin can interact with other medicines,

    The oral tablet of Griseofulvin can interact with other medicines, vitamins, or herbs that you might take. Your doctor can manage all of your drugs carefully to help prevent interactions. Be sure to inform the doctor whether you are taking any medications, supplements. Talk to your doctor or pharmacist to find out how the griseofulvin oral tablet can interact with anything else you're taking.


    Interactions that can make it less effective for your drugs

    These other drugs may not work as well when those drugs are used with griseofulvin. This is because it could be possible to decrease the amount of these medications in your body. These medications provide examples of:

    Warfarin: While you are taking griseofulvin, your doctor can increase your dosage of warfarin.

    Pills for birth control: You can have your doctor use the second form of birth control that works better. During your treatment with this medication, you should not get pregnant.

    Cyclosporine: While you are taking griseofulvin, your doctor can increase your cyclosporine dose.

    Aspirin and magnesium salicylate salicylates such as

    Griseofulvin might not function as well in treating your condition when you take griseofulvin with some medicines. This is because the amount of griseofulvin may be reduced in your body. These medications provide examples of:

    Barbiturates such as phenobarbital and butabarbital: The dose of griseofulvin can be increased by your doctor.

    Warnings from Griseofulvin

    The oral tablet Griseofulvin comes with many warnings.

    • Warning of allergies
    • A serious allergic reaction can be caused by Griseofulvin. Symptoms might include:
    • Breathing problems
    • Swelling of your tongue or throat

    Call your doctor or your nearest poison control center right away if you have an allergic reaction. Call 911 or go to the nearest emergency room if your symptoms are serious.

  • If you've already had an allergic reaction to it, don't try this drug again. It could be fatal to take it again (cause death).
  • Interaction with alcohol
  • You may be more susceptible to the effects of alcohol with this treatment. When you're taking this medicine, you can not drink alcohol. Talk to the doctor if you drink alcohol.
  • Warnings for persons who have such health problems

    For people with porphyria (an inherited blood disease): This medication should not be used. It can exacerbate the condition.

    For people with problems with their liver: This treatment will make the condition worse. You should not take this drug if you have liver disease. You are at increased risk of liver complications from this drug if you are taking other medications that can cause liver problems. If this prescription is safe for you, ask your doctor.

    For people with lupus: The condition can get worse with this medication. If this prescription is safe for you, ask your doctor.

    For other groups, warnings

    For pregnant women: Griseofulvin is a pregnancy medicine in group X. During pregnancy, Type X medications can never be used. No type of griseofulvin should be used by women who are pregnant.

    For women who are breastfeeding: In a child who is breast-feeding, griseofulvin can pass into breast milk and cause side effects. If you're breastfeeding your kid, speak to your doctor. If you want to stop breastfeeding or stop taking this drug, you will need to decide.

    For children:In children 2 years of age and younger, this medication has not been developed as safe and reliable. Moreover, protection at dosages greater than 10 mg/kg daily has not been identified in children older than 2 years of age.

    How to use Griseofulvin

    This dose knowledge is for an oral tablet of griseofulvin. It is not possible to provide all possible dosages and medication types here. Your dose, the type of the prescription, and how frequently you take the medicine will depend on:

    -Age of yours

    -The management of the disease

    -The seriousness of your condition

    -Some medical disorders you have

    How to respond to the first dose

    -Shapes and attributes

    -Generic: Griseofulvin, generic:

    -Form: Oral tablet, oral tablet (ultra-micro size)

    -Force: 125 mg, 250 mg

    -Form: Oral tablet, oral tablet (microsize)

    -Forces: 250 mg, 500 mg

    -Gris-PEG Brand: Gris-PEG

    -Form: Oral tablet, oral tablet (ultra-micro size)

    -Force: 125 mg, 250 mg

    -Dosage for infections of fungus

    -Force: 125 mg, 250 mg

    Dosage of adults (ages 18 years and older)


    Ultramicrosize:

    -Typical starting dose: 375 mg in a single or split dose. For infections that are not too serious, this dose is normal. That involves your scalp, hair, and body infections.

    -Dosage adjustments: If you have an infection that is more difficult to treat, such as a foot or nail infection, your doctor can tell you to take a split dose of 750 mg a day.

    -Treatment duration: 2 weeks to more than 6 months. Your medication time depends on how bad your infection is and where it is located.

    Microsize: -Microsize:

    -Typical starting dose: 500 mg in a single or split dose. For infections that are not too serious, this dose is normal.

    -Dosage adjustments: Your doctor can give you 750-1000 mg per day in split doses if you have an infection that is more difficult to treat. As your infection clears, your doctor can slowly decrease your dose.

    -Treatment duration: 2 weeks to more than 6 months. Your medication time depends on how bad your infection is and where it is located.

    Ultramicrosize:

    Typical administration: 3.3 mg/lb. Weight a day for the body

    For children weighing 35-60 lbs.: 125-187.5 mg daily

    For kids weighing more than 60 lbs.: 187.5-375 mg a day

    Children who have a scalp infection can need only one dose to treat their infection.

    Treatment duration: 2 weeks to more than 6 months. The period of care for your child depends on how serious the infection is and where it is located.

    Microsize: -Microsize:

    Typical dosage: 10 mg/kg per day of body weight

    For kids weighing 30-50 lbs: 125-250 mg a day

    For kids weighing more than 50 lbs: 250-500 mg daily

    Treatment duration: 2 weeks to more than 6 months. The period of care for your child depends on how serious the infection is and where it is located.

    Dosage for children (ages 0–1 year)

    In children younger than 2 years, this drug has not been studied. In people younger than 2 years of age, it should not be used

    Take as Advised

    For short-term therapy, oral tablet Griseofulvin is used. If you do not take it as recommended, it comes with risks.

    Missed Dose

    -If you unexpectedly stop taking the medication or do not take it at all, the infection will keep rising. It can spread also. If you miss a dose or do not take your medicine on time, your medicine will not work as well or may stop working altogether. A certain amount has to be in the bloodstream at all times for this drug to function properly.

    What to do if you miss a dose: As soon as you know, take the dose. Only a few hours before your next scheduled dose, if you recall, take just one dose.

    Over Dose

    You may have unsafe amounts of the medication in your body if you take too much. Your risk of side effects can be increased by this. Such side effects may become serious.

    Griseofulvin vs Itraconazol

    Griseofulvin
    Itraconazole
    Treating fungal skin, hair, and nail infections Gris-PEG (griseofulvin) may be a choice for the treatment of certain skin, hair, and/or nail fungal infections. It can only be used, however, if topical antifungal drugs have not worked for you. Treats infections of fungi. Sporanox (itraconazole) is an important oral medicine that treats fungal infections of several different forms. It has the ability to interfere with a lot of other drugs, however, and has a few extreme but uncommon side effects.
    Available in a generic, cheaper form. Available as a generic in the form of capsules.
    Dosage form: pill and liquid Dosage form: pill and liquid
    Risk of Liver damage Risk of liver toxicity

    Frequently Asked Questions:

    The oral tablet of Griseofulvin is used to treat fungal infections that can affect various parts of your body. Your hair, nails, and skin contain these.
    There may be headaches, nausea, vomiting, diarrhea, an upset stomach, exhaustion, dizziness, or difficulty sleeping. If any of these symptoms persist or worsen, immediately inform your physician or pharmacist.
    Griseofulvin is in a class of medicines called antifungal agents. A community of medicines that function in a similar way is a class of drugs. For the treatment of related conditions, these medications are also used. This medicine works by binding to a portion of the fungus in your body that triggers the infection.
    Griseofulvin care may last from a couple of weeks to several months. It is important that you continue to take it until you have fully cleared the infection, and then for another two weeks afterward.

    Citations:

    • Griseofulvin,https://europepmc.org/article/med/11908134
    • Griseofulvin Treatment,https://www.cabdirect.org/cabdirect/abstract/19592701220