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Aceclofenac

Aceclofenac

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By Medicover Hospitals / 16 Feb 2021
Home | Medicine | Aceclofenac
  • Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID). Aceclofenac is used for the treatment of pain and inflammation in osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. This drug works by blocking the effect of cyclooxygenase (COX) enzymes that make chemical prostaglandins at sites of injury or injury causing pain, swelling, and inflammation. Side effects of this drug include nausea, vomiting, diarrhea, flatulence, constipation, dyspepsia, somnolence, confusion, etc.
    1. Aceclofenac Uses
    2. Aceclofenac Side effects
    3. Aceclofenac Precautions
    4. Aceclofenac vs Paracetamol
    5. FAQ's

    Aceclofenac Uses:

    • Aceclofenac is used to relieve pain. It relieves pain and inflammation in conditions such as rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis..
    • Rheumatoid arthritis- Aceclofenac is used to treat symptoms such as swelling, pain, and stiffness of the joints associated with rheumatoid arthritis.
    • Osteo-arthritis- Aceclofenac is used to treat symptoms such as tender and painful joints associated with osteoarthritis.
    • Ankylosing Spondylitis - Aceclofenac is used to treat symptoms such as stiffness and pain associated with Ankylosing Spondylitis.

    How does it work

  • This medicine belongs to a class of non-steroidal anti-inflammatory drugs that help to relieve pain. Prostaglandin is responsible for pain, inflammation, swelling, and fever. It inhibits the action of cyclooxygenase in the brain that is involved in the production of prostaglandins.
  • Side Effects:

  • Some of the common side effects of aceclofenac are:
    • Abdominal pain
    • Constipation
    • Diarrhea
    • Nausea
    • Vomiting
    • Skin rash
    • Dizziness
    • Visual Disturbance
    • Flatulence
    • Flushing
    • Stomach Pain
    • Loss Of Appetite
    • Heartburn

    Aceclofenac Precautions:

  • Allergies- Avoid if you have a known allergy to Aceclofenac or other ANSIDs.
  • Asthma- Aceclofenac is not recommended if you have been diagnosed with asthma.
  • Bleeding - Aceclofenac is not recommended if you have any bleeding disorder. It may cause severe swelling and bleed in the stomach, colon, and anus.
  • Pregnancy- This medicine is not recommended in pregnant women.
  • Breast-nutrition- This medicine is not recommended for breastfeeding women.
  • Gastrointestinal bleeding- Aceclofenac may cause severe bleeding when taken for a long time. Elderly populations with a history of gastrointestinal disease are at higher risk.
  • Cardiac surgery- Aceclofenac should not be used to relieve pain before or after CABG (coronary artery bypass surgery).
  • Asthma- Aceclofenac is not recommended if you have asthma or a history of asthma in your family.
  • Impaired function of the kidney- Aceclofenac is not recommended if you have impaired kidney function.
  • Impaired function of the liver- Use with caution with an initial dose of 100 mg once daily for mild liver failure. Contraindicated in the severe failure of the liver.
  • Important information

  • Aceclofenac has been prescribed to relieve pain and inflammation.
  • Take this medicine with food or milk only to prevent stomach upset.
  • Take it according to the dosage prescribed by your doctor and correct the time duration. Long-term use may cause some serious complications such as stomach bleeding and kidney problems.
  • It may cause dizziness, somnolence, or visual disturbances. Use caution while driving or doing anything that needs to be concentrated.
  • Avoid drinking alcohol while taking Aceclofenac because it can cause excessive sleepiness and increase your risk of stomach problems.
  • Tell your doctor if you have a history of heart disease or stroke.
  • Your doctor may monitor your kidney function, liver function, and blood component levels on a regular basis if you are taking this medicine for long-term treatment.
  • Aceclofenac vs Paracetamol:

    Aceclofenac
    Paracetamol
    Formula: C16H13Cl2NO4. Formula: C8H9NO2.
    Molar mass: 354.1847 g/mol Molar mass: 151.163 g/mol
    Aceclofenac is a nonsteroidal anti-inflammatory drug Paracetamol is known as acetaminophen
    Aceclofenac is used for the relief of pains and inflammation Paracetamol is used for treating mild to moderate pain relief.

    Frequently Asked Questions:

    It is used for the treatment of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
    Aceclofenac film-coated tablets are indicated for pain relief and inflammation in osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Aceclofenac film-coated tablets are administered orally and should be swallowed whole with a sufficient quantity of liquid.
    The usual dose is one 100 mg tablet twice daily, preferably taken morning and evening. Take aceclofenac with food; it's ideal for a meal. This will protect your stomach from side effects such as indigestion and stomach irritation. Swallow your tablet with a drink of water.
    Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) and Paracetamol is an antipyretic drug (fever reducer). They work by blocking the release in the brain of certain chemical messengers that cause pain and fever.
    Aceclofenac and tenoxicam are similar in terms of safety and efficacy; and aceclofenac, 100 mg orally twice daily, is a safe, effective, and convenient treatment for active AS.
    Aceclofenac is used to relieve pain. It relieves pain and inflammation in conditions such as rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. Aceclofenac is a non-steroidal anti-inflammatory drug.
    In most cases, the average time taken by this medicine to reach its peak effect is about 1 day to 1 week. For the time period you need to use this medicine, please consult your doctor.
    Aceclofenac works by blocking the effect of natural substances called cyclooxygenase (COX) enzymes. These enzymes help to make other chemicals in the body called prostaglandins. Some prostaglandins are produced at injury or injury sites and cause pain and inflammation.
    This medicine is usually used once or twice a day. It is recommended to consult your doctor before use, as the frequency also depends on the condition of the patient.
    This medicine is advised to be taken orally. If you take it on an empty stomach, it might upset your stomach. Please consult your doctor before using it.
    It should be stored at room temperature, away from heat and direct sunlight.

    Citations:

  • aceclofenac, https://europepmc.org/article/med/10474963
  • Effects of aceclofenac,https://www.sciencedirect.com/science/article/abs/pii/0378517393903094