Keratitis Sicca: Signs, Causes, and How to Treat

Keratitis sicca, commonly known as dry eye disease, occurs when the eyes do not produce enough tears or the tears evaporate too quickly. This can lead to discomfort and potential damage to the surface of the eye. Causes of keratitis sicca can vary and may include factors such as aging, certain medications, environmental conditions like dry air or wind, and underlying health conditions. 

Understanding the underlying cause of dry eye is important in managing the condition effectively. By addressing the root cause, healthcare providers can tailor treatment plans to help alleviate symptoms and improve the quality of life for individuals experiencing dry eye. If you are experiencing symptoms of dry eye, speaking with an eye care professional can help determine the cause and explore appropriate treatment options.

What are the Symptoms of Keratitis Sicca

Keratitis sicca, commonly known as dry eye syndrome, can cause symptoms like persistent dryness, redness, and a feeling of grittiness in the eyes. Some people may experience blurred vision, sensitivity to light, and eye fatigue as well. 

In severe cases, keratitis sicca can lead to inflammation and damage to the cornea if left untreated. If you are experiencing any of these symptoms, it is essential to see an eye doctor for proper evaluation and management to prevent complications and improve eye comfort.

  • Dryness and grittiness in the eyes are common symptoms of keratitis sicca, also known as dry eye syndrome.
  • Blurred vision, especially after reading or using digital screens, can indicate keratitis sicca and the need for treatment.
  • Sensitivity to light, known as photophobia, is another symptom of keratitis sicca that can be bothersome for individuals.
  • Eye redness and inflammation may occur in keratitis sicca, leading to discomfort and a feeling of irritation in the eyes.
  • Difficulty wearing contact lenses due to discomfort and dryness may signal the presence of keratitis sicca and the need for evaluation by a healthcare provider.

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Causes of Keratitis Sicca

Keratitis sicca, commonly known as dry eye syndrome, can result from various factors. Environmental influences such as dry air, wind, or smoke can contribute to the condition by increasing evaporation of tears. Aging is another significant factor, as tear production tends to decrease with age. Certain medical conditions like autoimmune diseases or hormonal changes can also lead to dry eyes. Additionally, prolonged screen time or contact lens wear may exacerbate symptoms of keratitis sicca. Proper diagnosis and treatment are essential to manage this condition effectively and prevent complications.

  • Dry eye syndrome is a common cause of keratitis sicca, resulting from inadequate tear production or poor tear quality.
  • Prolonged use of contact lenses can lead to keratitis sicca due to reduced oxygen flow to the cornea.
  • Certain autoimmune diseases, such as Sjögren's syndrome, can trigger keratitis sicca by affecting tear production and quality.
  • Environmental factors like dry or windy conditions can exacerbate keratitis sicca symptoms by increasing evaporation of tears.
  • Aging can contribute to keratitis sicca as tear production tends to decrease with age, leading to insufficient lubrication of the eyes.

Types Of Keratitis Sicca

Keratitis sicca, also known as dry eye syndrome, can be categorized into two main types: aqueous-deficient and evaporative. Aqueous-deficient dry eye occurs when there is a lack of sufficient tear production by the lacrimal glands, leading to decreased lubrication and moisture on the eye's surface. 

On the other hand, evaporative dry eye results from factors such as meibomian gland dysfunction, which impairs the lipid layer of the tears, causing increased evaporation and inadequate protection for the ocular surface. Proper diagnosis and treatment are essential to manage both types of keratitis sicca effectively.

Types of Keratitis Sicca:

  •  Non-Sjögren’s Syndrome Keratitis Sicca: This type occurs in individuals without Sjögren's syndrome, often due to environmental factors or other underlying health conditions.
  • Sjögren’s Syndrome-Related Keratitis Sicca: This specific type is associated with Sjögren's syndrome, an autoimmune disorder that affects the body's moisture-producing glands. 
  • Neurotrophic Keratitis Sicca: In this type, damage to the corneal nerves impairs the normal tear production and leads to dryness of the eyes. 
  • Exposure Keratitis Sicca: Exposure to environmental factors like wind, sun, or dry air can cause this type

Risk Factors

Keratitis sicca, commonly known as dry eye syndrome, can be influenced by various risk factors. These may include advancing age, hormonal changes in women, certain medical conditions such as diabetes or autoimmune diseases, environmental factors like low humidity or exposure to wind or smoke, prolonged screen time leading to reduced blinking, certain medications like antihistamines or decongestants, and wearing contact lenses. Additionally, factors such as smoking, poor nutrition, and inadequate hydration can also contribute to the development or exacerbation of dry eyes.

  • Aging: Increasing age is a significant risk factor for developing keratitis sicca due to natural changes in tear production.
  • Environmental factors: Exposure to dry or windy conditions, dust, smoke, and low humidity can increase the risk of developing keratitis sicca.
  • Systemic diseases: Conditions like Sjogren's syndrome, rheumatoid arthritis, lupus, diabetes, and thyroid disorders are associated with an increased risk of keratitis sicca.
  • Medications: Certain medications, such as antihistamines, decongestants, antidepressants, and diuretics, can lead to dry eyes and increase the risk of keratitis sicca.
  • Contact lens wear: Improper use, extended wear, or poor hygiene practices

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Diagnosis of Keratitis Sicca

Diagnosing keratitis sicca involves a comprehensive examination by an eye care professional. The process typically starts with a detailed medical history to understand the patient's symptoms and possible risk factors. A thorough eye examination follows, which may include tests such as the Schirmer test to measure tear production, ocular surface staining to assess damage, and assessment of tear film quality. In some cases, additional imaging studies like corneal topography or meibography may be used to further evaluate the condition. By combining these various methods, healthcare providers can accurately diagnose keratitis sicca and develop an appropriate treatment plan for the patient's specific needs.

  • Diagnosis of keratitis sicca involves a thorough eye examination by an ophthalmologist.
  • Special tests may include Schirmer's test to measure tear production and tear film stability.
  • Fluorescein staining can help visualize corneal defects or damage caused by dry eye.
  • Evaluation of symptoms such as eye dryness, redness, and discomfort aids in diagnosis.
  • Tear osmolarity testing can assess the salt content in tears, indicating dry eye disease severity.

Treatment for Keratitis Sicca

Keratitis sicca, commonly known as dry eye syndrome, can be managed through various treatment options tailored to the underlying cause and severity of symptoms. Artificial tears are a common first-line approach to lubricate the eyes and provide relief. Prescription eye drops, such as cyclosporine or lifitegrast, may be recommended to reduce inflammation and improve tear production. In more severe cases, punctal plugs can help conserve tears by blocking tear drainage. Lifestyle changes like using a humidifier, avoiding irritants, and taking omega-3 supplements can also support eye health. In some instances, procedures like intense pulsed light therapy or LipiFlow may be considered for refractory cases. Consulting an eye care professional is essential to determine the most

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Frequently Asked Questions

How can keratitis sicca be identified through its signs?

Keratitis sicca can be identified through signs such as dry, red, and irritated eyes, blurred vision, sensitivity to light.

Are there specific things I should or shouldn't do when dealing with keratitis sicca?

Use preservative-free artificial tears and avoid using contact lenses to manage keratitis sicca.

Can keratitis sicca lead to other health issues?

Yes, untreated keratitis sicca can lead to corneal ulcers, eye infections, and vision problems. Regular eye care is important.

What are the best ways to manage keratitis sicca?

Manage keratitis sicca with artificial tears, warm compresses, and proper eye hygiene. Prescription medications or punctal plugs may be needed.

Are there any signs that keratitis sicca might recur after treatment?

Yes, symptoms like dryness, irritation, and redness may indicate a recurrence of keratitis sicca after treatment. Regular follow-ups are important.

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