Niacinamide is one of the two sources of vitamin B3 and the other one is nicotinic acid. Vitamin B3 is known as niacin. It supports skin health, improves energy metabolism, and helps manage certain chronic conditions.
Sources of Vitamin B3
Niacinamide
Nicotinic acid
Both have vitamin B3 activity but differ in chemical structure and health effects.
What Are the Uses of Niacinamide?
Niacinamide is widely used in skincare and health supplements for its anti-inflammatory, protective, and metabolic properties. The benefits of Niacinamide extend beyond skincare, also supporting overall health in various chronic conditions.
Conditions Niacinamide Helps Treat
Niacinamide Benefits for Skin Conditions
Plays a vital role in keeping the skin healthy.
Common additives in cosmetics and skincare products.
Shows anti-inflammatory effects when applied topically or taken as a supplement.
Used to treat skin disorders like acne and rosacea.
May Help Prevent Melanoma
A severe form of skin cancer linked to UV light exposure.
Niacinamide supplements improve DNA repair of UV-damaged skin.
May Help in Chronic Disease
Chronic Kidney Disease: Niacinamide can help lower phosphate levels in people with renal dysfunction.
Type 1 Diabetes: Supports and retains pancreatic beta cells, potentially slowing the disease's progression.
Secondary Benefits of Niacinamide
Added in moisturizers, serums, and cosmetics to improve skin texture, minimize pores, and balance oil production.
Sometimes used as an adjunct in laryngeal cancer therapy.
How Does Niacinamide Work in the Body (Mechanism of Action)?
It works by converting into coenzymes NAD+ and NADP+, essential for energy production, DNA repair, and cellular communication.
Helps repair skin damage caused by UV rays.
Reduces inflammation by calming the immune response.
Supports metabolic and insulin-regulating processes.
Niacinamide Dosage Guidelines
Dosage depends on the condition being treated and should always follow medical advice.
In clinical trials, niacinamide significantly reduced hyperpigmentation and improved skin lightness relative to the vehicle alone after 4 weeks of use. The research indicates that niacinamide is an effective skin lightening agent that works by inhibiting the transition of melanocytes from melanocytes to keratinocytes.
Niacinamide can be used by someone else. The ingredient is also appropriate for those with sensitive skin Niacinamide is "typically well tolerated and causes minimal skin irritation.
Niacinamide 500mg is commonly used to support skin health, reduce inflammation, improve joint function, and manage conditions like acne, arthritis, and vitamin B3 deficiency. It also helps in maintaining brain and liver health.
Research tells us that it is well tolerated by most people, niacinamide can be used twice daily. It works at any time of the year but it is especially useful in winter during cold, dry weather and heavy use of central heating.
Yes, niacinamide works well with most skincare ingredients. It is safe to use with Vitamin C (L-ascorbic acid), retinol, hyaluronic acid, and Zinc. Apply products in layers, starting from the thinnest to thickest.
Yes, niacinamide is gentle and soothing, making it suitable for sensitive skin. It helps reduce redness, calm irritation, and strengthen the skin barrier.
Yes, niacinamide helps fade dark spots and hyperpigmentation by slowing melanin production and improving overall skin tone with regular use.
Niacinamide is a soothing vitamin B3 that improves skin texture and tone, while retinol (vitamin A) boosts cell turnover and targets wrinkles and acne.
Niacinamide can be taken at any time, but it's best to take it with food to reduce the risk of stomach upset. If taken as a supplement, follow your doctor’s advice.
Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.
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