Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, swelling, and stiffness from conditions like arthritis, menstrual cramps, and injuries. It works by reducing inflammation-causing substances in the body and is available in tablet and liquid forms.

What are the Uses of Naproxen Tablet?

Naproxen tablets effectively relieve pain and reduce inflammation, improving mobility and comfort in many joint-related and other conditions. The benefits of naproxen include long-lasting pain relief and reduced swelling, making it easier to perform daily activities.

Conditions Treated by Naproxen

How Does Naproxen Work (Mechanism of Action)?

  • Naproxen Tablet works by blocking enzymes called cyclooxygenase (COX-1 and COX-2).
  • These enzymes help produce prostaglandins, which trigger inflammation, pain, and fever in the body.
  • By reducing prostaglandin production, naproxen lowers inflammation, swelling, and pain.
  • It is effective in treating arthritis, muscle pain, menstrual cramps, and other inflammation-related discomforts.

Naproxen Dosage

  • Generic: Naproxen Tablets (250 mg, 375 mg, 500 mg)
  • Brand: Naprosyn (naproxen) - 375 mg, 500 mg
  • Brand: Anaprox (Naproxen sodium) - 275 mg, 550 mg
  • Brand: Naprelan (Naproxen sodium) - 375 mg, 500 mg, 750 mg

How to Take Naproxen Tablets

Always follow your doctor's prescription for the correct dose and schedule to get the best results safely.

  • Extended-release tablets are usually taken once daily by mouth.
  • Immediate-release tablets are taken every 8-12 hours with a full glass of water.
  • Take at the same time each day if using regularly.

What Should I Do If I Miss a Dose of Naproxen?

  • If you miss a dose, take it as soon as you remember.
  • If your next dose is near, skip the missed dose and continue with your regular schedule.
  • Avoid taking a double dose to make up for the missed one.

What Happens If I Take Too Much Naproxen?

An overdose of Naproxen can be serious. Seek immediate medical help if you suspect an overdose.

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What are the Side Effects of Naproxen?

Understanding the side effects of Naproxen can help you use it'safely, avoid complications, and know when to seek medical attention if needed.

Common side effects of Naproxen

Serious side effects of Naproxen

Seek immediate medical attention for serious side effects.

Precautions Before Taking Naproxen

Before taking Naproxen, inform your doctor if you have any underlying health conditions or allergies, as these may increase the risk of side effects or complications.

Naproxen Warnings for Serious Health Conditions

  • Allergy Warnings: Seek immediate medical help for trouble breathing, throat swelling, hives, rash, or skin peeling.
  • Stomach Problems: Increases risk of bleeding or ulcers in those with a history of stomach or intestinal issues.
  • Kidney Disease: Can cause kidney damage with prolonged use in severe kidney disease patients.
  • Pregnancy and Breastfeeding: Consult your doctor before use.

Are There Any Age Restrictions for Naproxen?

Naproxen should be used with caution in both children and older adults. It is generally not recommended for children under 12 years old unless specifically prescribed by a doctor.

In older adults, the risk of side effects such as stomach bleeding, kidney problems, and high blood pressure may be higher.

Dosage and duration should be carefully monitored. Always consult a healthcare provider for age-appropriate guidance before using Naproxen.

Possible Interactions with Other Medications

Naproxen can interact with other medications, potentially increasing side effects or reducing the effectiveness of either drug. It's especially important to be cautious if you are taking:

  • Blood thinners (e.g., warfarin, aspirin)
  • Blood pressure medications (e.g., ACE inhibitors, diuretics, beta-blockers)
  • Other NSAIDs (like ibuprofen or diclofenac)
  • Corticosteroids (e.g., prednisone)
  • Antidepressants (like SSRIs)
  • Supplements and herbal remedies (like ginkgo biloba, garlic, or fish oil)

Always consult your doctor or pharmacist before combining naproxen with any prescription drugs, over-the-counter medications, or supplements. This helps prevent harmful interactions and ensures safe, effective treatment.

How Should Naproxen Be Stored?

Store Naproxen at room temperature (68-77°F / 20-25°C), away from heat, light, and moisture.

Keep it out of reach of children and pets to prevent accidental ingestion.

What Happens If Naproxen Is Not Stored Properly?

Improper storage may reduce the medicine's effectiveness and increase the risk of side effects or contamination.

Naproxen vs Ibuprofen

Naproxen Ibuprofen
Pain reliever that reduces inflammation Used for arthritis, fever, menstrual pain, etc.
Treats conditions like arthritis, menstrual cramps, and joint inflammation Relieves headache, dental pain, muscle aches, etc.
Serious side effects include:
  • Chest pain
  • Shortness of breath
  • Weakness
  • Difficulty speaking
  • Swelling of the face
  • High blood pressure
  • Bleeding and ulcers
Common side effects include:

References

Naproxen
Naproxen - StatPearls - NCBI Bookshelf
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Frequently Asked Questions

Before taking Naproxen, it's important to know your medical history, especially if you have a history of stomach ulcers, heart disease, high blood pressure, kidney disease, or liver disease. Inform your healthcare provider about any other medications you are currently taking, including over-the-counter drugs and herbal supplements, and whether you are pregnant, planning to become pregnant, or breastfeeding.

Naproxen should not be taken with other NSAIDs (nonsteroidal anti-inflammatory drugs) such as aspirin, ibuprofen, or celecoxib, as this can increase the risk of stomach bleeding. It should also be avoided with blood thinners like warfarin and certain medications for high blood pressure, as Naproxen can reduce their effectiveness.

While taking Naproxen, it is generally recommended to avoid alcohol, high-fat foods, and foods high in caffeine, as these can increase the risk of side effects, stomach bleeding, and liver damage.

Yes, naproxen is effective for relieving menstrual cramps as it reduces inflammation and eases pain during your period.

Naproxen reduces pain and inflammation. Acetaminophen relieves pain and fever but does not reduce inflammation.

Naproxen is both. It’s a non-steroidal anti-inflammatory drug (NSAID) that reduces inflammation and relieves pain.

Yes, naproxen can relieve headaches or mild migraines by reducing inflammation and blocking pain signals.


Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.

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