Misoprostol is a medicine used to treat stomach ulcers, abortion, and labor induction. It is commonly used to protect the stom
Misoprostol is a medicine used to treat stomach ulcers, abortion, and labor induction. It is commonly used to protect the stomach lining, manage pregnancy-related conditions, and treat postpartum bleeding. It is marketed under the Cytotec name. It is used alone, either with mifepristone or methotrexate, for abortions.
What are the Uses of Misoprostol Tablet?
Misoprostol offers multiple medical benefits depending on the condition being treated.
Conditions Misoprostol Treats
This medication helps in treating or managing a variety of health issues.
Stomach ulcers caused by NSAID use
Pregnancy termination (abortion)
Labor induction
Postpartum hemorrhage
Secondary Uses of Misoprostol
Apart from its main purposes, misoprostol may be used in special situations.
Miscarriage management
Cervical ripening before surgical procedures
Treatment of incomplete abortion
How Does Misoprostol Tablet Work (Mechanism of Action)?
Misoprostol works by mimicking prostaglandins-natural substances in your body that help control several functions.
It protects the stomach by:
Reducing acid secretion
Increasing mucus production to protect the stomach lining
In pregnancy-related uses:
It softens and dilates the cervix
Stimulates uterine contractions to expel pregnancy tissue or induce labor
Misoprostol Dosage
Misoprostol is typically available in tablet form, with the following dosage strengths used for different medical purposes:
Form
Strengths Available
Route of Administration
Common Uses
Tablet
100 mcg
Oral, Vaginal, Sublingual, Buccal
Prevention of gastric ulcers, labor induction, medical abortion
Tablet
200 mcg
Oral, Vaginal, Sublingual, Buccal
Medical abortion, labor induction, postpartum bleeding management
Note: The 200 mcg tablet is most commonly used, especially in gynecological and obstetric care. Always use under medical supervision.
How to use Misoprostol?
A patient data leaflet comes with this medicine. Read it thoroughly. Ask your doctor, nurse, or pharmacist if you have any questions concerning this drug.
The dosage is totally based on your medical conditions and your treatment responses.
Take it by mouth, usually four times a day, to minimize diarrhea and prevent stomach ulcers after meals and at bedtime, or as prescribed by your doctor.
Take it by mouth, exactly as directed by your doctor, if you are taking this abortion medication.
Your healthcare professional will insert it into your vagina if you are using this medication to start labor.
When using misoprostol, avoid taking magnesium-containing antacids because they may worsen the diarrhea it causes. Consult your physician or pharmacist if you need an antacid to help you choose a product.
Keep taking this medication for as long as you take NSAIDs for ulcer prevention. To get the most benefits from it, use this medication regularly.
If your condition continues to persist or worsens, please inform your doctor.
What should I do if the Dose is missed?
Taking your medicine regularly helps ensure better results.
If you forget a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed one.
Do not double up.
What Happens If I Overdose on Misoprostol?
Taking too much misoprostol can lead to serious health risks.
Symptoms may include:
Severe stomach cramps
Diarrhea
Drowsiness
Uterine contractions
Seek immediate medical help if you suspect an overdose.
Get a second opinion from trusted experts and makeconfident, informed decisions.
Daily alcohol consumption and smoking can increase the risk of stomach bleeding while on Misoprostol.
Limit alcohol and completely avoid smoking during treatment.
Use in Pregnancy
Misoprostol should not be used to prevent stomach ulcers during pregnancy due to the risk of harm to an unborn baby.
If you're of childbearing age, use reliable birth control while taking this medicine and for at least one month or one full menstrual cycle after stopping it.
Inform your doctor right away if you are pregnant or think you might be, to ensure proper care and avoid any risks related to your condition or treatment.
When Used With Mifepristone (for Abortion)
Misoprostol is sometimes used with Mifepristone to medically end a pregnancy.
Be aware that an incomplete abortion can rarely occur. To reduce risks:
Attend all follow-up appointments with your doctor.
Follow your doctor's emergency instructions carefully.
Mild to moderate vaginal bleeding is expected, but notify your doctor if symptoms worsen.
Breastfeeding
Misoprostol can pass into breast milk.
While it is unlikely to harm a nursing baby, speak with your doctor before breastfeeding to ensure it is safe.
What are the Interactions of Misoprostol?
Drug interactions can reduce effectiveness or increase risk of side effects.
Misoprostol may interact with:
Crofelemer
Eluxadoline
There are no major known interactions, but always consult your doctor about any medications, supplements, or herbal products you are using.
How to Store Misoprostol Medicine?
Keep away from sunlight, heat, and moisture in a dry position
Store at or below 77 degrees F (25 degrees C).
Do not flush or pour down the drain unless instructed
Keep out of reach of children
What Happens If Misoprostol Is Not Stored Properly?
Improper storage can reduce its effectiveness and safety.
Exposure to heat or moisture may degrade the medicine, leading to reduced potency or unexpected side effects.
Misoprostol vs Mifepristone
Misoprostol and mifepristone tablets uses include medical termination of early pregnancy, where they are commonly prescribed together to safely induce abortion by blocking pregnancy hormones and stimulating uterine contractions.
Misoprostol
Mifepristone
Formula: C22H38O5
Formula: C29H35NO2
Brand name Cytotec
Drug class- Antiprogestogen; Antiglucocorticoid
Molar mass: 382.5 g/mol
Molecular Weight: 429.6 g/mol
Is a medicine used to prevent and treat stomach ulcers, start work, cause abortion, and treat postpartum bleeding due to poor contraction of the uterus.
Is a medication that is used in combination with misoprostol to bring abortion during pregnancy.
Fetal tissue and the uterine lining would be loosened by misoprostol. The uterus will contract and, within a few hours, the cervix will dilate. It will cause bleeding and cramping as the tissue moves through the body.
Cramping and bleeding triggers this drug to drain the uterus. Cramping and bleeding typically begin 1-4 hours after misoprostol is taken in most individuals.
For improved effectiveness, vaginal administration of misoprostol is recommended. The prescribed dose of misoprostol is vaginally injected at 800 mcg (4 200-mcg tablets). The results of the study have shown that vaginal administration is more successful than oral misoprostol usage.
During pregnancy, Cytotec can cause the uterus to tear (uterine rupture). As the pregnancy progresses and if you have undergone surgery on the uterus, such as Cesarean delivery, the risk of uterine rupture increases. Extreme bleeding, hysterectomy, and/or maternal or fetal death may result in uterine rupture (tearing).
To allow the tablets to dissolve, lie down for about 30 minutes after you insert the misoprostol tablets. You can push them back in again if you notice the tablets falling out, or call us for instructions on what to do.
The side effects are common, typically lasting just 1 to 4 hours. If any of these side effects make you very uncomfortable, over-the-counter medicines can treat your symptoms. If over-the-counter treatments do not ease the symptoms, call them.
Cytotec is a brand name for the drug Misoprostol. They are the same medication, used to prevent ulcers and manage pregnancy-related conditions.
Misoprostol does not cause permanent infertility. It may affect the uterus temporarily, but normal fertility usually returns after use.
The maximum dose of misoprostol varies based on its use. For preventing gastric ulcers, it's typically 800 mcg per day (in divided doses). For medical abortion or labor induction, dosing depends on clinical guidelines and must be prescribed by a doctor. Always follow medical advice to avoid complications.
Misoprostol medicine is typically prescribed to adults. It should not be used without medical guidance in children or the elderly unless clearly advised by a doctor.
Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.
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