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By Medicover Hospitals / 11 Mar 2021
Home | Medicine | Midol

What is Midol ?

  • Midol is referred to as a nonsteroidal anti-inflammatory drug (NSAID). Midol is a brand of over-the-counter analgesics used to treat menstrual cramps and other symptoms associated with PMS and menstruation. It prevents the production of certain natural substances that cause inflammation in your body. Ask your doctor about non-drug therapies and using other drugs to treat your pain if you have a chronic condition like arthritis.
    1. Midol Uses
    2. Midol Side effects
    3. Precautions
    4. Overdose
    5. Storage
    6. Midol vs Advil
    7. Frequently Asked Questions
    8. Citations

    Midol Uses:

  • Midol is a pain reliever that is used to treat a variety of ailments including headaches, muscle aches, tendonitis, dental pain, and menstrual cramps. It also helps to relieve the pain, swelling, and stiffness associated with arthritis, bursitis, and gout attacks.
  • How to use Midol

    • If you're using an over-the-counter product, make sure you read all the instructions on the package before using it. If your doctor has prescribed this, read the Medication Guide provided by your pharmacist before using it. Inquire with your doctor or pharmacist if you have any concerns.
    • Take this medication orally, normally 2 or 3 times a day with a full glass of water (8 ounces/240 milliliters), as recommended by your doctor. After taking this medicine, don’t lie down for at least 10 minutes. Take this drug with food, milk, or an antacid to avoid stomach upset.
    • The dose is determined by your medical condition and treatment response. Take this drug at the lowest effective dose for the shortest time possible to minimize your risk of stomach bleeding and other side effects. Do not increase your dosage or take this medication more frequently than your doctor or the package label recommends. Continue to take this medication as prescribed by your doctor if you have an ongoing condition like arthritis.
    • It may take up to two weeks of regular use of this medication for certain conditions (such as arthritis) before you get the full benefit.
    • If you're taking this medication "as required" (not on a regular basis), keep in mind that pain relievers work best when taken as soon as the first signs of pain appear. If you wait until the pain becomes unbearable, the medication may not be effective.
    • Get medical assistance right away if your condition persists or worsens, or if you suspect you may have a serious medical problem. If you're using a nonprescription product to treat fever, call your doctor if it gets worse or lasts longer than three days.

    Midol Side Effects:

    • Upset stomach
    • Nausea
    • Heartburn
    • Headache
    • Drowsiness
    • Vomiting
    • Dizziness
    • Easy bruising
    • Bleeding
    • Painful swallowing
    • Ringing in the ears
    • Mental/mood changes
    • Kidney problems
    • Change in the amount of urine
    • Unexplained stiff neck
    • Vision changes
    • Symptoms of heart failure
    • Swelling ankles
    • Tiredness
    • Weight gain
    • Rash
    • Itching
    • Trouble breathing


    • If you are allergic to naproxen, aspirin, or other NSAIDs, or if you have any other allergies, tell your doctor or pharmacist before taking it. Inactive ingredients may be present in this product, causing allergic reactions or other issues.
    • NSAID drugs, such as naproxen, can cause kidney problems in some people. If you're dehydrated, have heart failure or kidney disease, are an older adult or take some drugs, you're more likely to have problems. To avoid dehydration, drink plenty of fluids as directed by your doctor, and report any changes in the amount of urine to your doctor right away.
    • This medication has the potential to cause gastrointestinal bleeding. Consumption of alcohol and tobacco on a regular basis, particularly when combined with this medicine, may increase your risk of stomach bleeding. Limit your drinking intake and quit smoking. Inquire with your doctor or pharmacist about the amount of alcohol you can consume safely.
    • If you are pregnant, consult your doctor. This drug has the potential to damage an unborn child and cause complications during normal labor and delivery. It is not advised to be used during pregnancy from 20 weeks to birth. If your doctor advises you to take this medication between 20 and 30 weeks of pregnancy, take the lowest effective dose for the shortest time possible. This drug should not be used after 30 weeks of pregnancy.
    • While taking this medication, older adults may be more susceptible to the stomach or intestinal bleeding, kidney problems, heart attack, and stroke.
    • This medication can pass into breast milk and have unfavorable effects on a nursing baby. Before breastfeeding, talk to your doctor.


    • Aliskiren, ACE inhibitors, angiotensin II receptor blockers, cidofovir, corticosteroids, lithium, and "water pills" are some of the products that may interact with this medication (diuretics such as furosemide).
    • When combined with other medications that can cause bleeding, this medication can increase the risk of bleeding. Antiplatelet drugs like clopidogrel, as well as "blood thinners" like dabigatran, enoxaparin, warfarin, are examples.
    • Because many medications contain pain relievers or fever reducers, read all prescription and nonprescription medicine labels carefully. These drugs are similar to naproxen, and taking them together may increase your risk of side effects. If your doctor has prescribed low-dose aspirin to prevent a heart attack or stroke (typically at doses of 81-325 milligrams per day), you should continue to take it unless your doctor tells you otherwise. The ability of aspirin to prevent heart attack and stroke may be reduced if naproxen is taken on a regular basis. Inquire about other pain/fever medications that may be available.


  • If someone has taken an overdose of this medicine and has serious symptoms such as passing out or trouble breathing, seek medical advice. Never take more than what is prescribed to you by your doctor.
  • Missed Dose:

  • If you forget to take any dose or by mistake miss a dose, take it as soon as you remember it. If it is already the time for the next dose, skip the forgotten dose. Take your next medicine at the regular time schedule. Do not double the dose.
  • Storage:

  • The medicine should not come in direct contact with heat, air, light and may damage your medicines. Exposure to medicine might cause some harmful effects or serious side effects. The medicine must be kept in a safe place and out of children’s reach.
  • Midol vs Advil:

    Midol is referred to as a nonsteroidal anti-inflammatory drug (NSAID) Advil is a nonsteroidal anti-inflammatory medication (NSAID).
    It prevents the production of certain natural substances that cause inflammation in your body. It works by lowering the levels of hormones in the body that cause inflammation and pain.
    Midol is a pain reliever that is used to treat a variety of ailments including headaches, muscle aches, tendonitis, dental pain, and menstrual cramps. Advil is used to treat pain and inflammation caused by a variety of ailments, including headaches, toothaches, back pain, arthritis, menstrual cramps, and minor injuries.

    Frequently Asked Questions:

    Period cramps, bloating, water retention, fatigue, muscle ache, backache, and headache are relieved. To combat fatigue and bloating, it contains acetaminophen (a pain reliever), caffeine (a diuretic), and pyrilamine maleate (an antihistamine).
    Midol contains acetaminophen with caffeine and pyrilamine maleate, combining a pain reliever, diuretic, and antihistamine to effectively relieve period cramps, headache, backache, muscle ache, bloating, and fatigue
    Because the antihistamine in this product may cause drowsiness, it can also be used as a sleep aid at night.
    Unless your doctor tells you otherwise, take this drug every 4 to 6 hours with a full glass of water (8 ounces/240 milliliters).
    Adults and children 12 years and older: take 2 caplets with water - repeat every 6 hours, as required - do not exceed 6 caplets per. Take 2 caplets with water if you're an adult or a child over the age of 12. As required, repeat every 6 hours.
    Adults and children aged 12 and up are advised to take Midol Complete. This means that teenagers should use Midol Complete gelcaps to treat premenstrual cramps and other period symptoms as well.
    It works efficiently, in most cases in under half an hour. I've been taking Midol for PMS and menstrual symptoms since I was 13 years old. I suffer from nagging lower back pain, which Midol helps to alleviate.


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