Midol Tablet: Uses, Side Effects, Dosage and Warnings
Written by Medicover Team and Medically Reviewed by Dr Lalitya Swarna Pethakamsetty, Gynecology
Midol is classified as a nonsteroidal anti-inflammatory drug (NSAID). It is an over-the-counter analgesic used to relieve menstrual cramps and symptoms associated with PMS and related discomfort.
Different types of Midol may contain different ingredients such as acetaminophen (paracetamol), caffeine, ibuprofen, or antihistamines. Always check the label for the exact composition.
Midol offers targeted pain relief and helps ease both physical and emotional PMS symptoms.
While primarily for menstrual pain, Midol may be used to relieve other types of mild-to-moderate pain when recommended by a doctor.
Midol is available in various dosage forms and formulations to target different menstrual symptoms, offering flexible options for daytime and nighttime relief.
| Product Name | Dosage Form | Active Ingredients | Primary Use |
|---|---|---|---|
| Midol Complete | Tablet | Acetaminophen + Caffeine + Pyrilamine maleate | Menstrual pain, bloating, fatigue |
| Midol Long Lasting Relief | Caplet (extended-release) | Naproxen sodium | Long-lasting relief from cramps and backache |
| Midol Teen Formula | Caplet | Acetaminophen + Pamabrom | Pain relief and bloating for teens |
| Midol Caffeine Free | Caplet | Acetaminophen + Pamabrom | For those sensitive to caffeine |
| Midol Menstrual Complete Gelcaps | Softgel | Acetaminophen + Caffeine + Pyrilamine maleate | Fast-acting pain and symptom relief |
| Midol PM | Caplet | Acetaminophen + Diphenhydramine citrate | Nighttime pain relief and sleep aid |
Follow your doctor's advice or package instructions carefully to use Midol safely and effectively.
If you're using an over-the-counter (OTC) Midol product, read all label directions thoroughly. For prescribed Midol, follow the medication guide provided by your pharmacist.
Do not lie down for at least 10 minutes after taking the medicine. This helps prevent irritation in the esophagus.
To reduce the risk of side effects like stomach bleeding, always use the lowest effective dose for the shortest possible time.
If someone has taken an overdose of this medicine and has serious symptoms, Seek immediate medical attention.
Common overdose symptoms include:
To reduce the risk of side effects or drug interactions, avoid the following:
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Get Second OpinionMost people tolerate Midol well, but some may experience mild to serious side effects.
Consult a doctor immediately if these symptoms occur or worsen.
Midol may not be safe for everyone.
Check with your doctor before use, especially if you have preexisting health conditions.
NSAIDs like naproxen can affect kidney function, especially in:
Stay well-hydrated and inform your doctor right away if you notice changes in urine output.
This medication can cause serious stomach or intestinal bleeding. The risk is higher if you:
To reduce the risk, limit alcohol, and consider quitting smoking. Speak to your doctor about safe alcohol consumption.
Seniors may be at higher risk for:
Extra caution is advised when this medication is prescribed to older patients.
Always consult your doctor or pharmacist before starting Midol, especially if you have underlying health conditions or are on other medications. Follow all usage instructions carefully to minimize the risk of side effects.
Are There Any Age Restrictions for Using Midol?
Midol is generally recommended for use in individuals aged 12 years and older. This age guideline ensures safe and effective use, as younger children may be more sensitive to the active ingredients, which include pain relievers, diuretics, or antihistamines depending on the formulation.
Using Midol below the recommended age without medical advice may lead to unwanted side effects or incorrect dosing. Always consult a healthcare provider for children under 12.
Alcohol or Food Interactions
Consuming alcohol or tobacco while taking Midol can increase the risk of stomach bleeding.
Limit alcohol intake and avoid smoking to reduce complications.
Before taking Midol, it's important to be aware of potential drug interactions. Combining it with certain medications may raise the risk of serious side effects or reduce the effectiveness of your current treatments.
Midol (which contains naproxen, a nonsteroidal anti-inflammatory drug or NSAID) may interact with the following:
These combinations can affect kidney function or increase the risk of other serious side effects.
Using Midol along with other medications that affect blood clotting can raise your risk of bleeding. Be cautious if you are taking:
Many over-the-counter and prescription medications already contain pain relievers or fever reducers, which are similar to naproxen. Taking multiple medications with similar ingredients can increase the risk of side effects like stomach ulcers or kidney damage. Always check labels carefully.
If your doctor has advised you to take low-dose aspirin (81-325 mg daily) for heart attack or stroke prevention, do not stop taking it unless instructed by your doctor.
Taking naproxen regularly may reduce aspirin's effectiveness in preventing heart attacks and strokes. Consult your doctor or pharmacist for safer pain relief alternatives if you're on daily aspirin therapy.
Proper storage ensures the effectiveness and safety of the medicine.
| Midol | Advil |
|---|---|
| Midol is referred to as a nonsteroidal anti-inflammatory drug (NSAID) | Advil is a nonsteroidal anti-inflammatory medication (NSAID). |
| It prevents the production of certain natural substances that cause inflammation in your body. | It works by lowering the levels of hormones in the body that cause inflammation and pain. |
| Midol is a pain reliever that is used to treat a variety of ailments including headaches, muscle aches, tendonitis, dental pain, and menstrual cramps. | Advil is used to treat pain and inflammation caused by a variety of ailments, including headaches, toothaches, back pain, arthritis, menstrual cramps, and minor injuries. |

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040-68334455Midol combines acetaminophen with caffeine and pyrilamine maleate, providing a pain reliever, diuretic, and antihistamine to effectively relieve period cramps, headache, backache, muscle ache, bloating, and fatigue.
Midol contains an antihistamine that may cause drowsiness, making it suitable as a sleep aid at night.
Adults and children 12 years and older can take 2 caplets every 6 hours, not exceeding 6 caplets in 24 hours. Always follow label instructions or your doctor's advice to avoid side effects.
Midol Complete gelcaps are recommended for adults and teenagers aged 12 and up to treat premenstrual cramps and other period symptoms.
Midol typically works within half an hour to alleviate symptoms of PMS and menstrual discomfort, including lower back pain.
Midol is not generally recommended during pregnancy without a doctor's advice, as it may contain ingredients unsafe for the baby. Always consult your healthcare provider.
Midol may help mild back pain related to menstrual cramps, but it's not a general-purpose pain reliever for all back pain types. Use other pain relievers if unrelated to periods.
Most Midol formulas already contain NSAIDs like ibuprofen or naproxen. Taking them together may lead to overdose. Check ingredients or ask your doctor before combining.
It’s best to take Midol with food to avoid stomach upset. However, if needed, it can be taken on an empty stomach-just watch for any discomfort.
Yes, Midol can help relieve headaches, especially those related to menstrual symptoms, as it contains pain-relieving ingredients like acetaminophen.
Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.