Lisinopril: Uses, Side Effects, Storage and Precautions
Written by Medicover Team and Medically Reviewed by Dr Kanchan M Bhambare, Cardiology
Lisinopril is a widely prescribed medication that belongs to the class of angiotensin-converting enzyme (ACE) inhibitors. It is commonly used for managing high blood pressure, treating heart failure, and improving survival after heart attacks. Lisinopril is particularly effective in preventing kidney complications in people with diabetes and in lowering the risk of cardiovascular events like strokes and heart attacks.
Lisinopril is an ACE inhibitor that works by relaxing blood vessels so blood can flow more easily. It is typically used as a first-line treatment for hypertension (high blood pressure) and is also prescribed for heart failure, post-heart attack care, and kidney protection in type 2 diabetes patients.
Discover how this medication helps support heart and circulatory system health, while improving overall cardiovascular function.
While not its primary indication, it may also be used in patients with certain types of chronic kidney disease (CKD) and in those undergoing long-term cardiovascular risk management.
Lisinopril works by blocking the action of the angiotensin-converting enzyme (ACE), which is part of a system that narrows blood vessels and raises blood pressure. By inhibiting this enzyme, lisinopril causes blood vessels to relax and widen, lowering blood pressure and reducing strain on the heart.
Lisinopril should be taken exactly as prescribed by your doctor. It is usually taken once daily, with or without food. Dosage depends on your medical condition and response to treatment. Your doctor may adjust the dose based on your blood pressure readings or kidney function over time.
Take the missed dose as soon as you remember. If it's almost time for your next dose, skip the missed one do not double up to catch up.
In case of an overdose, seek emergency medical attention immediately. Symptoms of overdose may include
Get a second opinion from trusted experts and makeconfident, informed decisions.
Get Second OpinionLearn about the potential reactions your body might have to this medicine, from mild discomforts to symptoms that require medical attention.
If any side effects worsen or become severe, consult your doctor immediately.
Understand who should take extra care before starting this drug, including specific health conditions and lifestyle factors that may increase risk.
Lisinopril is typically used in adults. Pediatric use is determined by a physician and may be approved in certain cases, such as hypertension in children aged 6 and above.
Find out how lisinopril might react when taken with other drugs, and why it's important to review all your prescriptions with your healthcare provider.
Lisinopril may interact with:
Let all your healthcare providers know you're taking lisinopril.
Poor storage (e.g., moisture, heat) may reduce the effectiveness of the medication. Keep out of reach of children and pets. Dispose of expired or unused medication'safely-do not flush down the toilet.
| Lisinopril | Enalapril |
|---|---|
| Lisinopril is an ACE inhibitor used to treat high blood pressure, heart failure, and heart attacks. | Enalapril is an ACE inhibitor used to treat high blood pressure, diabetic kidney problems, and heart failure. |
| Typically used as a first-line treatment for high blood pressure. | Enalapril oral tablet treats hypertension, heart failure, and asymptomatic left ventricular dysfunction. |
| Used to treat heart failure and people who have had a heart attack. | Can treat heart failure but not heart attacks. |

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040-68334455Long-term use of lisinopril can potentially lead to heart, artery, and kidney damage if untreated, increasing the risk of stroke, heart failure, or kidney failure.
Lisinopril, an ACE inhibitor, relaxes and widens blood vessels, lowering blood pressure and improving heart efficiency. It also protects kidneys and slows diabetic kidney disease progression.
Yes, it's recommended to drink plenty of water while on lisinopril to prevent dehydration, which can sometimes occur due to its effects on blood pressure and kidney function.
Avoid excessive consumption of high-potassium foods like bananas, oranges, potatoes, tomatoes, squash, and dark leafy greens while on lisinopril, as it can increase blood potassium levels.
Lisinopril can cause swelling in the intestines, potentially leading to bowel obstruction, a serious complication that may be difficult to diagnose.
Common side effects of lisinopril include nausea, headaches, anxiety, insomnia, and drowsiness. Allergic reactions should be monitored closely.
Lisinopril's effects on blood pressure typically last beyond its 12-hour half-life, with some impact persisting up to 24 hours after ingestion.
Lisinopril can cause gastrointestinal symptoms like abdominal pain, cramping, nausea, and vomiting in some individuals.
Lisinopril effectively lowers both systolic and diastolic blood pressure, with superior effects on systolic pressure compared to some other medications.
While beneficial for many kidney conditions, lisinopril and other ACE inhibitors can have adverse effects on kidney function if not properly monitored.
Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.