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By Medicover Hospitals / 10 Mar 2021
Home | Medicine | Lisinopril

What is Lisinopril?

  • Lisinopril is an angiotensin-converting enzyme inhibitor medication used to treat high blood pressure, heart failure, and heart attacks. It is typically used as a first-line treatment for high blood pressure. It is also used to prevent kidney problems in people who have type 2 diabetes.
    1. Lisinopril Uses
    2. Lisinopril Side effects
    3. Precautions
    4. Overdose
    5. Storage
    6. Lisinopril vs Enalapril
    7. Frequently Asked Questions
    8. Citations

    Lisinopril Uses:

  • Lisinopril is a blood pressure medication. Lowering high blood pressure aids in the prevention of strokes, heart attacks, and kidney problems. It is also used to treat heart failure and to increase survival following a heart attack. Lisinopril is an ACE inhibitor, which is a type of medication. It works by relaxing blood vessels, allowing blood to flow more freely.
  • How to use lisinopril oral:

    • As directed by your doctor, take this medication orally, with or without food, once daily.
    • If you're taking this medication as a suspension, shake the bottle thoroughly before each dose. Use a special measuring device to carefully measure the dose. You should not use a regular spoon because you may not get the correct dose using those.
    • The dosage is determined by your medical condition as well as your response to treatment. The dosage for children is also determined by their weight.
    • To reduce the possibility of side effects, your doctor may advise you to begin this medication at a low dosage and gradually increase it.
    • To get the most out of this medication, take it on a routine basis. Take it at the same time every day to help you remember. Even if you feel healthy, continue to take this medication. The majority of people with high blood pressure do not feel ill.
    • It may take 2 to 4 weeks before you see the full benefit of this medication for the treatment of high blood pressure. It may take weeks to months before you see the full benefit of this medication for the treatment of heart failure. Inform your doctor if your condition does not improve.

    Lisinopril Side Effects:

    • Blurred vision
    • Cloudy urine
    • Confusion
    • A decrease in urine output
    • Dizziness
    • Faintness
    • Sweating
    • Tiredness
    • Weakness
    • Chest pain
    • Chills
    • Common cold
    • Cough
    • Diarrhea
    • Difficulty breathing
    • Ear congestion
    • Fever
    • Headache
    • Loss of voice
    • Nausea
    • Runny nose
    • Sneezing
    • Sore throat
    • Vomiting


    • Inform your doctor if you are allergic to lisinopril or any other ACE inhibitors (such as benazepril), or if you have any other kind of allergies. Inactive ingredients present in this product may cause allergic reactions or other problems. For more information, consult your pharmacist.
    • Before using this medication, inform your doctor or pharmacist of your medical history, particularly of: a history of an allergic reaction characterized by swelling of the face, lips, tongue, throat (angioedema), blood filtering procedures (such as LDL apheresis, dialysis), and a high level of potassium in the blood.
    • This medication may cause dizziness. You may become dizzy if you consume alcohol or marijuana (cannabis). Do not drive, operate machinery, or do anything else that requires alertness until you are confident that you can do so safely. Limit your intake of alcoholic beverages. If you use marijuana, consult your doctor (cannabis).
    • Excessive sweating, diarrhea, or vomiting may result in excessive water loss (dehydration) and increase your risk of lightheadedness. Consult your doctor if you have diarrhea or vomiting. Unless otherwise directed by your doctor, drink plenty of fluids to avoid dehydration.
    • This product has the potential to raise your potassium levels. Visit your doctor before using potassium supplements.
    • Older adults may be more sensitive to the drug's side effects, particularly dizziness and potassium level increases.
    • This medication should not be used while pregnant. It is potential to harm an unborn child.
    • It is unknown whether this medication is excreted in breast milk. Before you breast-feeding, talk to your doctor.


  • Some products which might interact with this drug include aliskiren, certain drugs that weaken the immune system and increase the risk of infection (such as everolimus, sirolimus), lithium, drugs that may increase the level of potassium in the blood (such as ARBs including losartan/valsartan, birth control pills containing drospirenone), and sacubitril.
  • If you are receiving injections for bee/wasp sting allergy (desensitization) while also taking lisinopril, you may experience a severe reaction. Ensure that all of your doctors are aware of the medications you are taking.
  • Overdose:

  • If someone has taken an overdose of this medicine and has serious symptoms such as passing out or trouble breathing, seek medical advice. Never take more than what is prescribed to you by your doctor.
  • Missed Dose:

  • If you forget to take any dose or by mistake miss a dose, take it as soon as you remember it. If it is already near to the time of the next dose, skip the forgotten dose. Take your next dose at the regular time. Do not double the dose.
  • Storage:

  • Keep the tablets and suspension in a dark, dry place away from light and moisture. Keep out of the bathroom. After 4 weeks, discard any unused suspension. Keep all medications far away from children and pets.
  • Unless otherwise directed, do not flush medications down the toilet or pour them down a drain. When this product has expired or is no longer needed, properly dispose of it. Consult your pharmacist or a waste disposal company in your area.
  • Lisinopril vs Enalapril:

    Lisinopril is an angiotensin-converting enzyme inhibitor medication used to treat high blood pressure, heart failure, and heart attacks. Enalapril is an ACE inhibitor medication that is used to treat high blood pressure, diabetic kidney problems, and heart failure.
    It is typically used as a first-line treatment for high blood pressure. Enalapril oral tablet is prescribed to treat hypertension, heart failure, and asymptomatic left ventricular dysfunction.
    Lisinopril is a medication that can be used to treat heart failure and to treat people who have had a heart attack. Enalapril can be used to treat heart failure but not heart attacks.

    Frequently Asked Questions:

    If it persists for an extended period of time, the heart and arteries may cease to function properly. This can cause damage to the blood vessels in the brain, heart, and kidneys, leading to a stroke, heart failure, or kidney failure.
    Lisinopril, like other ACE inhibitors, relaxes and widens blood vessels. This lowers your blood pressure and allows your heart to pump blood more efficiently throughout your body. This can help to alleviate the symptoms of heart failure. It protects your kidneys and slows the progression of diabetic kidney disease.
    Drink plenty of water every day while taking this medication. It is possible to take lisinopril with or without food.
    Foods high in potassium are among the lisinopril food interactions. Lisinopril has the ability to raise blood potassium levels. As a result, using salt substitutes or eating high-potassium foods may cause complications. Bananas, oranges, potatoes, tomatoes, squash, and dark leafy greens are all foods to avoid in excess.
    ACE inhibitors can lead to swelling in the small and large intestines, which can lead to bowel obstruction. This, too, can be a potentially fatal complication. Doctors may struggle to diagnose abdominal angioedema because symptoms can be confused with other digestive disorders
    Nausea, headaches, anxiety, insomnia, drowsiness, nasal congestion, and sexual dysfunction can all be side effects of lisinopril. If there are symptoms or signs of an allergic reaction, such as swelling of the face, lips, tongue, or throat, lisinopril should be discontinued.
    6 Lisinopril's elimination half-life is only 12 hours, but it has been shown to have some BPlowering effects after 24 hours
    Some side effects or common symptoms such as diffuse abdominal pain, cramping, nausea, and emesis can make this medicine hard for the stomach.
    Lisinopril lowers systolic and diastolic blood pressure more than HCTZ. In terms of diastolic blood pressure reduction, lisinopril is comparable to atenolol and metoprolol but superior in terms of systolic blood pressure reduction.
    ACE inhibitors can be both beneficial and detrimental to your kidneys. These are drugs that end in -il, such as lisinopril, enalapril, and ramipril. ACE inhibitors are widely used to treat high blood pressure and heart failure.


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