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By Medicover Hospitals / 07 April 2021
Home | Medicine | Cefepime


  • Cefepime is a cephalosporin antibiotic of the fourth generation.Cefepime has a broad spectrum of activity against Gram-positive and Gram-negative bacteria, with activity against both being greater than that of third-generation agents.
    1. Cefepime Uses
    2. Cefepime Side effects
    3. Precautions
    4. Interactions
    5. Dosage
    6. Storage
    7. Cefepime vs Ceftriaxone
    8. Frequently Asked Questions
    9. Citations

    Cefepime Uses:

  • Cefepime is an antibiotic that is used to treat a wide range of bacterial infections. This medication is a cephalosporin antibiotic. It works by preventing bacterial growth.
  • How to use Cefepime Solution?

  • As directed by your doctor, this medication is administered via injection into a muscle or vein. The dosage is dependent on your medical condition as well as your response to treatment.
  • If you are using this medication at home, make sure you understand all preparation and usage instructions from your doctor. Before using, visually inspect this product for particles or discoloration. If either of these conditions exists, do not use the liquid.
  • Thaw the bag of frozen pre-mixed solution at room temperature or in the refrigerator before using it. Allow the bag to sit at room temperature for at least 1 hour after it has been thawed in the refrigerator. Do not thaw in a water bath or in the microwave. After thawing, shake the bag vigorously and squeeze it to check for leaks. If the bag leaks, discard the solution. After thawing, do not refreeze the solution.
  • Use this antibiotic at evenly spaced intervals for the best results. Use this medication at the same time to help you remember.
  • Even if your symptoms go away after a few days, keep taking this medication for the full amount of time prescribed. Stopping the medication too soon may cause a relapse.
  • Side Effects:

    • Headache
    • Diarrhea
    • Pain
    • Redness
    • Swelling
    • Bleeding on the injected area
    • Watery or bloody stools
    • Stomach cramps
    • Fever
    • Rash
    • Nausea
    • Vomiting
    • Itching
    • Difficulty in swallowing
    • Breathing difficulty
    • Swelling of the throat or tongue
    • Seizures
    • Confusion
    • Hallucinations
    • Coma
    • Fever
    • Sore throat
    • Chills
    • Other signs of infection


  • Inform your doctor or pharmacist if you are allergic to it or other antibiotics (such as penicillins, other cephalosporins), or if you have any other allergies. Inactive ingredients of this product can cause allergic reactions or some other problems.
  • Cefepime may impair the effectiveness of live bacterial vaccines (such as typhoid vaccine). Unless your doctor tells you otherwise, do not have any immunizations or vaccinations while taking this medication.
  • If you are pregnant, notify your doctor. It can harm an unborn child. If you become pregnant, consult your doctor as soon as possible.
  • It is not known whether this medication is excreted in breast milk. Before breastfeeding, consult your doctor.
  • Interactions

  • Drug interactions can change the way your medications function or put you at risk for serious side effects. Keep a record of everything you use and share it with your doctor and pharmacist. This medication may interfere with certain lab tests (including urine glucose tests), potentially resulting in false results.
  • Overdose

  • If someone has taken an overdose of this medicine and has serious symptoms such as trouble breathing, seek medical advice immediately. Never take more doses than what is prescribed to you by your doctor.
  • Missed Dose

  • It is necessary to take each dose of this medication on time. If you forget a dose, contact your doctor or pharmacist as soon as possible to arrange for a new dosing schedule. Do not double the dose.
  • Storage:

  • The medicine must not come in contact with heat, air, light and may damage the drug. The medicine must be kept in a safe place and far away from children’s reach.
  • Cefepime vs Ceftriaxone

    Cefepime is a cephalosporin antibiotic of the fourth generation.Cefepime has a broad spectrum of activity against Gram-positive and Gram-negative bacteria Ceftriaxone, also known as Rocephin, is an antibiotic that is used to treat a variety of bacterial infections.
    Cefepime is an antibiotic that is used to treat a wide range of bacterial infections. This medication is a cephalosporin antibiotic, which is a type of antibiotic. Used to treat bacterial infections that are serious or life-threatening, such as E. coli, pneumonia, or meningitis. Ceftriaxone is also used to prevent infection in patients undergoing specific types of surgery.
    It works by preventing bacterial growth. It works by interfering with the cell wall formation of bacteria. Ceftriaxone weakens the bonds that hold the bacterial cell wall together, allowing holes to form. This kills the bacteria that are causing the infection.

    Frequently Asked Questions:

    Cefepime injection is used to treat bacterial infections such as pneumonia, skin, urinary tract, and kidney infections. Cefepime injection is used to treat abdominal (stomach area) infections in conjunction with metronidazole (Flagyl).
    Cephalosporin antibiotics Rocephin (ceftriaxone sodium) and Maxipime (cefepime hydrochloride) are used to treat a variety of bacterial infections, including severe or life-threatening infections.
    Cefepime does not work when taken orally (as a tablet or capsule).
    Cefepime is a cephalosporin antibiotic. It works by combating bacteria in the body. Cefepime injection is used to treat a wide range of bacterial infections, including those that are severe or life-threatening.
    Cefepime is a broad-spectrum cephalosporin antibiotic that has been used to treat bacteria that cause pneumonia, skin infections, and urinary tract infections. Pseudomonas, Escherichia, and Streptococcus species are among these bacteria.
    The majority of broad-spectrum antibiotics used to treat sepsis are active against Gram-positive organisms.
    It is extremely soluble in water. MAXIPIME for Injection is available in 500 mg, 1 g, and 2 g cefepime strengths for intramuscular or intravenous administration.
    These patients experienced prolonged confusion with temporospatial disorientation and hallucinations for 2–8 days after ceasing cefepime. A quarter of the cases also had bilateral distal myoclonus.
    Cases of cefepime neurotoxicity in patients with renal failure have been reported infrequently. Cefepime's neurotoxicity may be underestimated, and the frequency of its neurotoxic effects may be underappreciated.


  • Efficacy and safety of cefepime,
  • Cefepime Dose,