What is Canagliflozin ?

Canagliflozin is used in adults with type 2 diabetes mellitus to improve blood sugar control in conjunction with diet and exercise. The medication is also used to reduce the risk of death from heart attack, stroke, or heart failure in adults who have type 2 diabetes and heart disease.

Canagliflozin is also used to reduce the risk of last-stage kidney disease, or death from heart problems in adults who have type 2 diabetes and kidney problems.

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Canagliflozin Uses

Canagliflozin is used to control high blood sugar in people with type 2 diabetes in conjunction with a proper diet and exercise program. Controlling high blood sugar levels can help prevent kidney damage, blindness, nerve problems, limb loss, and sexual function issues. Canagliflozin is also used to decrease the risk of death from heart attack or stroke in people with type 2 diabetes and heart disease. Canagliflozin 100mg is also used by people with type 2 diabetes and kidney disease to reduce the risk of dialysis, heart disease death, and hospitalization for heart failure. Canagliflozin works by increasing sugar removal by the kidneys.

How to use Canagliflozin Tablet?

Before you take canagliflozin, and each time you get a refill, read the Medication Guide provided by your doctor. If you have any worries, consult your doctor or pharmacist.

Take this medication orally as prescribed by your doctor, usually once a day before your first meal. The dosage is determined by your medical condition, response to treatment, and any other medications you are taking.

To get the most out of this medication, take it on a regular basis.

Canagliflozin Side Effects

Bloating
Bloody or cloudy urine
Decreased frequency or amount of urine
Increased thirst
Indigestion
Itching
Loss of appetite
Lower back or side pain
Nausea
Redness
Dizziness
Drowsiness
Trouble breathing
Tiredness
Weakness
Vomiting
Weight gain

Precautions

Tell your doctor or pharmacist if you are allergic to canagliflozin or if you have any other allergies. Inactive ingredients present in this product might cause allergic reactions or other problems. For more information, consult your pharmacist.

Tell your doctor or pharmacist about your medical history, especially if you have: kidney disease, dehydration, low blood pressure, heart failure and mineral imbalances (such as high potassium levels).

Due to extremely low or high blood sugar levels, you may experience blurred vision, dizziness, or drowsiness.

Limit your alcohol consumption while taking this medication because it increases your chances of developing low blood sugar and a high ketone level.

When your body is stressed, it may be more difficult to control your blood sugar (such as due to fever, infection, injury, or surgery). Furthermore, if you eat less or are unable to eat due to these conditions, this can result in a high ketone level while taking this medication.

Older adults may be more sensitive to the drug's side effects, particularly dizziness/fainting (usually when standing), dehydration, and bone loss.

This medication should not be used during pregnancy. Consult your doctor before using.

It is not known that this medication passes into breast milk or not. Before breastfeeding, ask your doctor.

Interactions

Many drugs can have an effect on your blood sugar, making it more difficult to control. Before beginning, discontinuing, or changing any medication, consult your doctor about how the medication may affect your blood sugar. Check your levels of blood sugar on a regular basis and share the results with your doctor. If you experience symptoms of high or low blood sugar, contact your doctor right away. Your diabetes medication, exercise program, or diet may need to be adjusted by your doctor.

Overdose

Overdose of a drug can be accidental. If you have taken more than the prescribed Pregabalin tablets there is a chance of getting a harmful effect on your body’s functions. Overdose of this medicine can lead to some medical emergency.

Missed Dose

If you forget to take any dose of this medicine, skip the missed dose and return to your regular dosing schedule. Do not double the dose.

Storage

The medicine should not come in direct contact with heat, air, light and may damage your medicines. Exposure to medicine might cause some harmful effects or serious side effects. The medicine must be kept in a safe place and out of children’s reach.

Canagliflozin vs Dapagliflozin

Canagliflozin	Dapagliflozin
Canagliflozin is used in adults with type 2 diabetes mellitus to improve blood sugar.	Dapagliflozin is an oral diabetes medication that aids in blood sugar control.
It reduces blood sugar level by causing the kidneys to excrete more glucose in the urine.	Dapagliflozin works by assisting the kidneys in removing glucose from the bloodstream.
Canagliflozin is used to control high blood sugar in people with type 2 diabetes in conjunction with a proper diet and exercise program.	Dapagliflozin is used in adults with type 2 diabetes mellitus, along with diet and exercise, to improve blood sugar control.

Citations

Canagliflozin https://link.springer.com/article/10.1007%2Fs40005-018-0385-5

Canagliflozin Dosage https://search.proquest.com/openview/dea6006468b2bdb2a9e2eb645ca1cee3/1?pq-origsite=gschola

Frequently Asked Questions

What is canagliflozin used for?

Canagliflozin is used to lower blood sugar levels in people with type 2 diabetes, along with diet and exercise and, in some cases, other medications (a condition in which blood sugar levels increases because the body does not produce or use insulin normally).

Does canagliflozin cause weight gain?

Canagliflozin has been associated with weight loss in some rare cases you might gain weight.

How long does it take for Canagliflozin to work?

Although steady-state levels are achieved in 4 to 5 days, clinical effectiveness with Invokana varies from person to person and may take longer due to your unique factors such as age, weight, additional medications you take, kidney or liver function, or other medical conditions.

Can you take canagliflozin with metformin?

To treat type 2 diabetes, a combination of canagliflozin and metformin is used in conjunction with a healthy diet and exercise. In patients with type 2 diabetes and heart or blood vessel disease, this medication is also used to reduce the risk of a heart attack, stroke, or death.

Does canagliflozin cause hypoglycemia?

Canagliflozin is generally well-tolerated, but it is associated with adverse events (AEs) related to the mechanism of action (GMOs, osmotic diuresis-, and volume depletion-related AEs). Canagliflozin has a low incidence of hypoglycemia in patients who are not taking insulin or a sulfonylurea.

Does canagliflozin cause edema?

If you have fever, unusual tiredness or weakness, or pain, tenderness, redness, or swelling between and around your anus and genitals, see your doctor right away. This medication may cause severe allergic reactions such as anaphylaxis or angioedema.

Is canagliflozin safe?

Canagliflozin is an effective diabetes medication with potential cardiovascular and renal benefits, as well as generally well-tolerated diabetes. It is considered safe.

Is canagliflozin safe in pregnancy?

In pregnant women, there is insufficient data to determine a drug-associated risk for major birth defects and miscarriage; animal data have shown adverse renal effects with administration during the renal development period, in the late second and third trimesters of human pregnancy.

Can canagliflozin cause kidney failure?

It can increase your risk of kidney damage

Can canagliflozin cause increased urination?

Yes, the side effects can lead to a change in the amount or frequency of urination.