Canagliflozin (brand name Invokana, available as Invokana 100 mg) is an oral SGLT2 inhibitor prescribed to adults with type 2 diabetes. Taken as canagliflozin tablets or canagliflozin tab, it helps lower blood sugar, protect the heart, and support kidney health when used alongside diet and exercise.
What is Canagliflozin?
Canagliflozin is used in adults with type 2 diabetes mellitus to improve blood sugar control in conjunction with diet and exercise. The medication is also used to reduce the risk of death from
Heart attack
Stroke
Heart failure in adults
Individuals with heart disease and type 2 diabetes
Canagliflozin is also used to reduce the risk of last-stage kidney disease or death from heart problems in adults who have type 2 diabetes and kidney problems.
What Are the Uses of Canagliflozin Tablets?
Canagliflozin tablets are primarily used to manage blood sugar levels in adults with type 2 diabetes, helping reduce the risk of serious complications.
It also offers heart and kidney protection, especially in patients with existing cardiovascular or renal conditions.
Primary Canagliflozin Uses
Helps lower blood sugar levels in adults with type 2 diabetes
Reduces the risk of heart attack, stroke, and hospitalization for heart failure
Protects kidney function and delays progression to end-stage kidney disease
Canagliflozin 100 mg Uses
The canagliflozin 100 mg tablet is commonly prescribed for:
Daily blood sugar management in type 2 diabetes
Patients with existing heart or kidney conditions for added protective benefits
Secondary Uses of Canagliflozin Tab
Used off-label in some cases to manage insulin resistance
May support weight loss and blood pressure control as a secondary effect
How Does Canagliflozin Work?
Canagliflozin tablets belong to a class of drugs called SGLT2 inhibitors. They work by blocking the sodium-glucose co-transporter-2 (SGLT2) protein in the kidneys. This prevents the body from reabsorbing excess glucose, causing it to be passed out through urine. As a result, blood sugar levels are lowered naturally.
Dosage Instructions for Canagliflozin Tablets
The dosage of canagliflozin varies based on individual health needs and should be taken exactly as prescribed.
Take canagliflozin tab once daily, preferably before your first meal.
The usual starting dose is 100 mg per day, which may be adjusted by your healthcare provider.
Always follow your doctor's instructions closely.
What Should I Do If I Miss a Dose of Canagliflozin?
If you miss your dose, take it as soon as you remember unless it's near the time of your next dose. Do not double the dose to catch up.
What Happens If I Overdose on Canagliflozin?
If you overdose on Canagliflozin, you may experience low blood sugar, dehydration, dizziness, or excessive urination. Seek immediate medical attention if you suspect an overdose.
This medication may cause changes in your blood sugar. You should know the symptoms of low and high blood sugar and what to do if you have these symptoms.
Are There Any Age Restrictions for Canagliflozin Tablets?
Canagliflozin 100 mg tablets are only approved for adults. They are not recommended for children or adolescents under 18 years of age.
Alcohol or Food Interactions
Alcohol can raise the risk of side effects like low blood sugar or high ketones.
No specific food restrictions, but it's best taken with or before a meal.
Possible Interactions with Other Medications
Taking Canagliflozin tablets alongside other medications can sometimes cause adverse effects or reduce the effectiveness of either drug. It's essential to be aware of potential interactions and to consult your doctor or pharmacist before combining treatments.
Canagliflozin tablets may interact with:
Diuretics (can increase risk of dehydration)
Insulin or sulfonylureas (can cause low blood sugar)
ACE inhibitors or ARBs (monitor kidney function)
Herbal supplements (consult your doctor)
Keep a full list of all medicines and supplements you take and share it with your healthcare provider.
How Should Canagliflozin Be Stored?
Proper storage of canagliflozin ensures its effectiveness and safety throughout its shelf life.
Store Invokana (canagliflozin) at room temperature (20-25° C or 68-77° F)
Keep away from moisture, sunlight, and heat
Store in its original container, tightly closed
Keep out of reach of children
What Happens If Canagliflozin Is Not Stored Properly?
Improper storage may lead to loss of effectiveness or chemical degradation, increasing the risk of adverse effects or reduced blood sugar control. Always store the canagliflozin tab as directed.
Canagliflozin vs Dapagliflozin
Canagliflozin
Dapagliflozin
Canagliflozin is used in adults with type 2 diabetes mellitus to improve blood sugar control.
Dapagliflozin is an oral diabetes medication that helps manage blood sugar levels in adults with type 2 diabetes.
It lowers blood sugar by promoting the excretion of excess glucose through the urine via the kidneys.
Dapagliflozin works similarly by helping the kidneys eliminate more glucose from the bloodstream through urine.
Canagliflozin is prescribed alongside a proper diet and exercise program to enhance glycemic control.
Dapagliflozin is also used in combination with diet and exercise to improve overall blood sugar control.
Canagliflozin is used to lower blood sugar levels in people with type 2 diabetes, along with diet and exercise and, in some cases, other medications (a condition in which blood sugar levels increase because the body does not produce or use insulin normally).
Canagliflozin has been associated with weight loss in some rare cases you might gain weight.
Although steady-state levels are achieved in 4 to 5 days, clinical effectiveness with Invokana varies from person to person and may take longer due to your unique factors such as age, weight, additional medications you take, kidney or liverfunction, or other medical conditions.
To treat type 2 diabetes, a combination of canagliflozin and metformin is used in conjunction with a healthy diet and exercise. In patients with type 2 diabetes and heart or blood vessel disease, this medication is also used to reduce the risk of a heart attack, or stroke.
Canagliflozin is generally well-tolerated, but it is associated with adverse events (AEs) related to the mechanism of action (GMOs, osmotic diuresis-, and volume depletion-related AEs). Canagliflozin has a low incidence of hypoglycemia in patients who are not taking insulin or a sulfonylurea.
If you have fever, unusual tiredness or weakness, or pain, tenderness, redness, or swelling between and around your anus and genitals, see your doctor right away. This medication may cause severe allergic reactions such as anaphylaxis or angioedema.
In pregnant women, there is insufficient data to determine a drug-associated risk for major birth defects and miscarriage; animal data have shown adverse renal effects with administration during the renal development period, in the late second and third trimesters of human pregnancy.
It can increase your risk of kidney damage.
Canagliflozin 100 mg tablets are prescribed to be taken once daily, typically in the morning.
Common side effects of Canagliflozin drug may include urinary tract infections, increased urination, and potential genital yeast infections.
Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.
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