Human Metapneumovirus (HMPV) - Overview

Written by Medicover Team and Medically Reviewed by Dr Meghana Reddy S , Pulmonologist


If you've recently started coughing, feeling tired, or having trouble breathing there is a chance you might be dealing with human metapneumovirus. This respiratory hMPV virus spreads through droplets and often feels like a cold at first. 

But if you’re feeling sick each day, it’s a sign your lungs may be inflamed and need medical attention.

What is Human Metapneumovirus?

HMPV is one of the toughest viral infections that immediately attacks your respiratory system, including ENT (Ear, Nose, Throat and Lungs). Can easily spread through when someone coughs, sneezes and contact with un-hygenic surfaces. 

While these are mild symptoms, it first attacks the low immune system respiratory system like children and older adults. Early detection is key to managing the infection and avoiding complications like bronchitis or pneumonia.


What are the Human Metapneumovirus Symptoms?

When someone is infected with metapneumovirus, the symptoms can feel a lot like the common cold or flu, especially in the early stages. Here’s what to watch for

  • Persistent Cough: The cough can start out dry and irritating, and in some cases, it may begin to bring up mucus. It might get worse at night or after physical activity, and can sometimes linger even after other symptoms fade.
  • Runny or Stuffy Nose: You might notice your nose constantly dripping, or it may feel blocked and difficult to breathe through. This congestion can affect your sense of smell and make breathing less comfortable.
  • Sore Throat: A scratchy, dry, or painful throat is common

hMPV Severe Symptoms:

  • Difficulty breathing or rapid breathing
  • Chest tightness or pain
  • High fever that doesn’t come down
  • Wheezing, especially in children or older adults

What are the Types of Human Metapneumovirus?

hMPV is divided into two major genetic categories, called Genotype A and Genotype B:

Two Main Genotypes of hMPV

Genotype A

  • This is one of the most common forms.
  • It has two key subgroups:
    • A1
    • A2, which is further broken down into:
      • A2a
      • A2b
      • A2c

Genotype B

  • Also widely circulating in the population.
  • It includes: B1 and B2

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What Causes Human Metapneumovirus?

Human Metapneumovirus (hMPV) is an easily spread diseased virus that occurs easily, especially among children, older adults, and people with weak immunity. It is a common cause of respiratory infections and often goes around during colder seasons. 

Knowing how it spreads and who’s most at risk can help reduce exposure.

Human Metapneumovirus Causes:

These are the direct reasons people get infected with hMPV:

  • Coughing and sneezing: The virus spreads through droplets released into the air when an infected person coughs or sneezes nearby.
  • Touching your eyes, nose, or mouth after coming into contact with contaminated surfaces or people.
  • Seasonal spread, especially during peak circulation periods which typically occur over the 12 months in waves often peaking in late winter and early spring.
  • Hands shake with someone who is affected with the hmpv disease, un wearing a mask will be a great chance for disease spread.

What are the risk factors for human metapneumovirus?

Anyone can get HMPV, but you’re at a higher risk for severe illness if you:

  • Are younger than 5 (especially premature infants) or older than 65.
  • Have a weakened immune system (from conditions like HIV, cancer or autoimmune disorders, or from medications that suppress your immune system).
  • Having asthma or COPD.

What are the steps for Human Metapneumovirus Diagnosis?

If someone has breathing problems that just aren’t going away, especially a baby, an elderly person, or someone with low immunity it’s important to find out what’s really causing it. In some cases, a virus like Human Metapneumovirus (hMPV) might be the reasons

hMPV Diagnostic Tests:

  • Nasopharyngeal Swab Test: A soft swab is gently inserted into the nose or throat to collect a sample for laboratory testing.
  • Polymerase Chain Reaction (PCR) Test: This advanced molecular technique detects nucleic acid from the virus and is one of the most sensitive ways to confirm hMPV.
  • Antigen Detection Tests: These identify specific proteins from the virus in the respiratory sample.
  • Serologic Testing: Used occasionally to detect antibodies in the blood, which helps in retrospective diagnosis or during outbreak studies.
  • Chest X-rays: Recommended when breathing issues are present to check for lung involvement or pneumonia.
  • Bronchoscopy: Performed in severe cases to visually examine the airways and collect deeper respiratory samples.

A timely and accurate diagnosis helps doctors provide the right care and avoid further health issues.


What are the Human Metapneumovirus Treatment Options?

Treatment for hMPV virus can be effected in your day to day life, especially in children, older adults, or people with other health conditions timely treatment becomes important.

hMPV Supportive Care

Rest and Hydration

  • Patients are mostly advised to get enough rest and stay well-hydrated to help the body naturally fight the infection.

Over-the-counter Medications

  • Medicines like paracetamol or ibuprofen may be used to manage fever, body aches, or general discomfort.

Cough Suppressants

  • These may help relieve chest tightness and nasal blockage, especially when symptoms interfere with sleep or breathing.

Although there is no specific antiviral for Human Metapneumovirus, proper care can help manage symptoms and prevent complications.


When to See a Human Metapneumovirus Doctor?

While most hMPV infections are mild and can be managed with rest and home care, there are times when medical help is necessary. Knowing when to consult a doctor can help prevent complications, especially in high-risk individuals.

Consult a hMPV doctor if you or your child experiences:

  • Fever lasting more than 3 days
  • Severe cough or wheezing that interferes with breathing
  • Difficulty breathing especially in infants or elderly adults
  • Continuous chest discomfort or tightness
  • Lack of appetite, fatigue, or signs of dehydration (dry mouth, low urine output, dizziness)
  • Symptoms worsening instead of improving after basic home care

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What is the Recovery Process After Human Metapneumovirus Treatment?

After getting treated for Human Metapneumovirus (hMPV) infections, most people start feeling better within a few days. But the time it takes to fully recover can be different for everyone. 

It mainly depends on how strong the symptoms were and if the person already has any respiratory illnesses like asthma or COPD. Some people may need extra care to help their lungs heal properly.

Post-Treatment Follow-Up Care

To make sure the recovery goes well, doctors may suggest:

  • Check-up after 10 days if symptoms are still there
  • Lung tests for people who already have breathing problems like asthma or COPD
  • Seeing a specialist if the person had serious issues like pneumonia or bronchiolitis
  • Keeping track of symptoms and changing medicines if needed to help recovery

What Precautions Can Help Prevent Human Metapneumovirus?

Human Metapneumovirus (hMPV) spreads easily from person to person, especially in crowded places like schools, hospitals, or at home. Simple daily habits can help protect you and others especially young children and people who get sick easily

How to Prevent the Spread of hMPV? 

To prevent the spread of Human Metapneumovirus (hMPV), simple hygiene habits and mindful behavior in public spaces play a key role.

Lifestyle Modifications

  • Wash hands regularly, especially after touching public surfaces
  • Avoid shaking hands when sick or around someone with cold-like symptoms
  • Cover your mouth and nose while coughing and sneezing to protect others
  • Avoid touching your eyes, nose, or mouth with unwashed hands
  • Keep frequently touched surfaces clean at home and in shared spaces
  • Encourage children to follow proper hygiene at school and daycare
  • Stay home and rest if you’re feeling unwell to avoid spreading the virus

Regular Screenings

  • People with chronic lung or heart conditions should schedule routine health checkups
  • In high-risk groups, early testing during respiratory illness helps in quick diagnosis and isolation
  • Human metapneumovirus death rate is very low but symptoms can show the adverse effects

Human Metapneumovirus (hMPV) is a common viral infection that affects the respiratory system, particularly in young children, older adults, and people with weakened immunity. 

While many cases are mild and improve with rest and care, some can lead to serious complications if not monitored. Staying alert to symptoms, seeking timely diagnosis, and following preventive steps like good hygiene can help manage and reduce the spread of infection. 

Always consult a hMPV Specialist if symptoms persist or worsen.


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Frequently Asked Questions

Yes, reinfection with hMPV is possible, especially in children and older adults. Immunity after infection may not be long-lasting, so repeat infections can occur.

Currently, no approved vaccine exists for hMPV. Prevention mainly relies on hygiene measures like frequent handwashing and avoiding contact with infected individuals.

You can be contagious with hMPV for 5 to 10 days after symptoms start. In some people, especially those with weak immunity, viral shedding can continue for up to 2 weeks.

While rare, Human Metapneumovirus can cause death in high-risk individuals like infants, older adults, and people with chronic illnesses if severe complications develop.

The mortality rate is generally low, but in hospitalized or immunocompromised patients, it may range from 3% to 10%, especially when associated with complications like pneumonia.

No, hMPV is a different virus but causes similar respiratory symptoms as RSV or flu. It often affects the same age groups and spreads through coughing, sneezing, or direct contact.

Infants, elderly adults, and people with weakened immune systems or chronic illnesses are most at risk of developing severe symptoms or complications from hMPV.

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