Antithyroid Microsomal Antibody (AMA) Test

The Antithyroid Microsomal Antibody (AMA) Test, also known as the thyroid peroxidase test, measures the levels of antibodies in the blood against thyroid peroxidase. This enzyme plays a vital role in producing thyroid hormones. The presence of these antibodies indicates damage to the thyroid cells or the presence of other autoimmune diseases. The thyroid gland produces hormones that help in the regulation of the body's metabolism.

What is the AMA test used for?

The Antithyroid Microsomal Antibody (AMA) Test is used to evaluate thyroid abnormalities and diagnose autoimmune disorders such as primary biliary cirrhosis (PBC). This test is useful in determining the underlying cause of thyroid disorders, such as Hashimoto thyroiditis, and whether an autoimmune condition is causing thyroid gland damage.

Why do I need an AMA Test?

If you are suffering any of the following symptoms, you may require an AMA test:

An AMA test is also recommended for individuals who have a history or indication of hepatobiliary disease. The doctor may also advise you to do the test to determine the antithyroid microsomal antibody levels.

What happens during an AMA Test?

The doctor will clean the area with an antibiotic, wrap the arm in a tourniquet, and select a vein, usually from the back of the hand or inside the elbow. To collect blood, they will put a tiny needle into the vein. The blood sample is then taken to the lab for testing.

What is the normal range of antithyroid microsomal antibodies?

The normal range for Antithyroid Microsomal Antibody (AMA) values is 0.0-9.0 IU/mL. A negative AMA test result shows an absence of antithyroid microsomal antibodies, implying normal immune system activity. The standard range may differ slightly between laboratories. High AMA levels may indicate preeclampsia,miscarriage, or premature birth.

How often should you take the AMA test?

The Antithyroid Microsomal Antibody (AMA) Test is not a standard laboratory test. It is only required if you have abnormal thyroid-stimulating hormone (TSH) test results or symptoms indicating thyroid hormone levels that are abnormal. The test may also be required to check for primary biliary cirrhosis (PBC).

What is a positive AMA test?

A positive test results in an autoimmune disease or thyroid problem, especially if the test results are high. This could happen for various reasons, including:

How long does it take to get AMA test results?

The results of the blood test assessing AMA levels are usually available in less than one week (ranging from three to ten days). After the result is ready, the health providers will explain it to you.

Are any preparations needed for the AMA test?

To get accurate results, the doctor may advise you to fast for six hours before the test. One should also inform the doctor about any medications or prescriptions you have been using. This is done to make sure that nothing will undermine the test result. Other than that, no extra preparations are required.

Frequently Asked Questions

1. Is an AMA test painful?

You may experience mild discomfort during collecting the blood sample, but the procedure is generally painless.

2. What does a negative AMA test result mean?

A negative AMA test result means that there are no antithyroid microsomal antibodies present in your blood, which indicates normal immune system function.

3. What does a positive AMA test result mean?

A positive AMA test result means that there are antithyroid microsomal antibodies present in your blood, which may indicate autoimmune disorders like Hashimoto's thyroiditis.

4. What are the risks associated with an AMA test?

The risks associated with an AMA test are minimal and include mild bruising or bleeding at the site of the blood draw.

5. Can an AMA test diagnose thyroid cancer?

No, an AMA test cannot diagnose thyroid cancer. It is used to evaluate thyroid function and detect autoimmune diseases.

6. Can stress affect AMA test results?

No, stress is unlikely to affect AMA test results.

7. Can an AMA test be performed at home?

No, an AMA test cannot be performed at home and must be conducted by a healthcare professional in a laboratory setting.

8. What is the cost of the AMA test?

The cost of the AMA test is approximately Rs. 1100/-