Written by Medicover Team and Medically Reviewed by
Dr Bharadwaj
Top Medications for Treating Nasal Polyps
Nasal polyps are soft, noncancerous growths that form in the nose or sinuses. They can lead to a stuffy nose, loss of smell, and repeated infections. Luckily, there are several medicines that can help shrink the polyps and relieve symptoms. In this article, we’ll look at the best medications used to treat nasal polyps.
Corticosteroid Nasal Sprays for Nasal Polyps
Corticosteroid nasal sprays are often the first line of treatment for nasal polyps. They help to reduce inflammation and shrink the polyps, making it easier to breathe. Some common corticosteroid nasal sprays include:
Fluticasone (Flonase)
Mometasone (Nasonex)
Budesonide (Rhinocort)
Beclomethasone (Beconase)
How to Use Corticosteroid Nasal Sprays?
Using a corticosteroid nasal spray is relatively straightforward. Here are the general steps:
Shake the bottle gently.
Remove the cap and prime the spray if it's the first use.
Tilt your head slightly forward.
Insert the nozzle into one nostril while closing the other with your finger.
Spray and breathe in gently.
Repeat for the other nostril if required.
Potential Side Effects
While corticosteroid nasal sprays are effective, they can have side effects, such as:
In more severe cases, your doctor might prescribe oral corticosteroids. These are generally used for short periods due to their potential for serious side effects. Common oral corticosteroids include:
Prednisone
Methylprednisolone
How Oral Corticosteroids Work?
Oral corticosteroids work by reducing inflammation throughout your body, including your nasal passages. They can be very effective, but their use is typically limited to avoid long-term complications.
Potential Side Effects
Side effects of oral corticosteroids can be more severe than nasal sprays and may include:
Decongestants can help reduce the swelling and congestion associated with nasal polyps. They are available in both oral and nasal spray forms. Common decongestants include:
Pseudoephedrine (Sudafed)
Oxymetazoline (Afrin)
How to Use Decongestants?
If you're using a decongestant nasal spray, follow steps similar to those for corticosteroid nasal sprays. For oral decongestants, follow the dosage instructions provided on the packaging or by your healthcare provider.
Potential Side Effects
Decongestants can also have side effects, including:
Biologic therapies are a newer option for treating nasal polyps, particularly for those who don't respond to other treatments. These medications target specific pathways in the immune system to reduce inflammation. Examples include:
Dupilumab (Dupixent)
Omalizumab (Xolair)
How Biologic Therapies Work?
Biologic therapies are usually administered via injection and work by targeting specific molecules involved in the inflammatory process. They can be very effective but are often reserved for severe cases due to their cost and the need for regular injections.
Potential Side Effects
Possible side effects of biologic therapies can include:
Leukotriene inhibitors are another option for managing nasal polyps. These medications work by blocking substances called leukotrienes, which can cause inflammation. Examples include:
Montelukast (Singulair)
Zafirlukast (Accolate)
How Leukotriene Inhibitors Work?
Leukotriene inhibitors are usually taken orally and can help reduce the size of nasal polyps and alleviate symptoms like congestion and runny nose.
Potential Side Effects
Side effects of leukotriene inhibitors can include:
Antihistamines can help manage symptoms of nasal polyps, mainly if allergies are a contributing factor. Common antihistamines include:
Cetirizine (Zyrtec)
Loratadine (Claritin)
Fexofenadine (Allegra)
How Antihistamines Work?
Antihistamines work by blocking histamine, a substance in your body that causes allergy symptoms. They can help reduce runny nose, sneezing, and itching.
Potential Side Effects
Possible side effects of antihistamines can include:
Sometimes, a combination of medications is the best approach to managing nasal polyps. Your healthcare provider may recommend using a corticosteroid nasal spray in conjunction with an antihistamine or a leukotriene inhibitor to achieve the best results.
How to Follow Combination Therapies?
Always follow your healthcare provider's instructions when using combination therapies. They will tailor the treatment plan to your specific needs and adjust it as necessary based on your response to the medications.
When to See a Doctor?
While over-the-counter medications can help manage symptoms, it's crucial to consult a healthcare provider for a proper diagnosis and treatment plan. If you experience any of the following, seek medical attention:
Severe or worsening symptoms
Symptoms that don't improve with treatment
Side effects from medications
Frequent nosebleeds
Your health is everything - prioritize your well-being today.
Managing nasal polyps can be challenging, but several effective medications can help reduce symptoms and improve your quality of life. From corticosteroid nasal sprays to biological therapies, there's a range of options to consider. Always consult your healthcare provider to determine the most suitable treatment plan for your specific condition.
Frequently Asked Questions
Common side effects include nosebleeds, sore throat, headache, and nasal dryness from steroid sprays. Oral steroids may cause weight gain, mood changes, and high blood pressure with long-term use.
Medication, especially nasal or oral steroids, can shrink or control polyps, reducing the need for surgery. If symptoms are severe or keep coming back, surgery may still be recommended.
Medication like nasal steroid sprays or oral corticosteroids can shrink or control polyps but usually doesn't remove them completely. Some people may still need surgery if symptoms persist.
Dupilumab (Dupixent) is a newer drug used to treat nasal polyps. It’s an injectable biologic that helps reduce inflammation and polyp size, especially in people with asthma or severe sinus problems.
Yes, an ENT (Ear, Nose, and Throat) specialist can remove nasal polyps through a procedure called endoscopic sinus surgery. It's done if the medication doesn't work or if symptoms are severe.
Steroid nasal sprays like fluticasone, mometasone, or budesonide are commonly used. They reduce inflammation and help shrink polyps. The “best” one depends on your response and the doctor’s advice.
You may experience a stuffy nose, reduced smell, facial pressure, and sinus infections. Polyps are not cancerous, but they can affect breathing and comfort. Treatment helps manage symptoms.
Large nasal polyps might be visible near the nostrils, but most are deeper inside the nasal passages. An ENT uses a nasal scope or imaging to check for them properly.