Zaleplon: Uses, Side Effects, Storage and Precautions
Written by Medicover Team and Medically Reviewed by Dr Siva Anoop Yella, Psychiatry
Zaleplon is a prescription sedative-hypnotic medication primarily used to treat short-term insomnia. It helps people who have difficulty falling asleep but is not intended to help with staying asleep through the night. Zaleplon works quickly and is known for its rapid action and short half-life, making it effective for individuals who experience difficulty initiating sleep.
Zaleplon is a non-benzodiazepine hypnotic from the pyrazolopyrimidine class. It acts on the central nervous system by enhancing the activity of gamma-aminobutyric acid (GABA), a neurotransmitter that promotes sleep. It is commonly prescribed for short-term management of insomnia due to its rapid onset and minimal next-day effects.
Zaleplon is primarily prescribed to manage short-term insomnia. It helps users fall asleep faster, providing relief from sleep difficulties and promoting a healthier sleep routine.
Conditions Zaleplon Treats
Secondary Uses of Zaleplon
Zaleplon enhances the effect of GABA, a calming neurotransmitter in the brain. By binding selectively to the GABA-A receptor complex, it'slows down brain activity, helping individuals fall asleep faster. Unlike benzodiazepines, Zaleplon has minimal muscle-relaxing or anti-anxiety properties and is less likely to cause dependence with short-term use.
Zaleplon dosage is typically tailored by a healthcare provider based on individual needs and medical considerations. It's usually taken right before bedtime, only when there is enough time for a whole night's sleep.
Note: Dosage may vary based on age, health condition, and doctor's assessment.
Zaleplon should only be taken when needed, at bedtime. If you miss a dose and it's almost morning or too late at night, skip the missed dose and continue with your regular schedule. Never take a double dose to make up for a missed one.
Symptoms of overdose may include:
Seek emergency medical help immediately if an overdose is suspected.
Get a second opinion from trusted experts and makeconfident, informed decisions.
Get Second OpinionLike many medications, Zaleplon may cause side effects, ranging from mild symptoms like drowsiness to more uncommon reactions. Monitoring your response is essential.
Call your doctor right away if severe symptoms occur.
Before using Zaleplon, certain health conditions and lifestyle factors should be discussed with a doctor. Caution is advised in specific cases such as pregnancy, mental health disorders, or substance abuse history.
Not recommended for use in children. Use with caution in elderly patients due to a higher risk of dizziness and confusion.
Zaleplon may interact with other prescription or over-the-counter drugs, especially those affecting the nervous system. Always inform your doctor about all medications and supplements you're taking.
Zaleplon can interact with:
Always inform your doctor about all medications and supplements you are taking.
Store Zaleplon in a cool, dry place away from light and moisture. Keep it out of reach of children and dispose of it'safely once it expires or is no longer needed.
| Zaleplon | Xanax |
|---|---|
| Used for insomnia (difficulty falling asleep). | Used for treating anxiety disorders and panic attacks. |
| Sedative/hypnotic, known as a hypnotic nonbenzodiazepine. | Anti-anxiety medication. |
| Does not help with staying asleep longer or reducing night awakenings. | Provides short-term relief from anxiety symptoms. |
| Common side effects: Drowsiness, dizziness, lightheadedness, lack of coordination, numbness, tingling in hands. |
Serious side effects: Drowsiness, fatigue, constipation, dry mouth. |

Still have questions? Speak with our experts now!
040-68334455Sonata (zaleplon) helps you fall asleep, but the medications don’t help you stay asleep for a longer period of time. Ambien (zolpidem) helps to fall asleep and remain asleep, but can be habit-forming and may be more likely to cause side effects than most sleep medications.
For a brief period of time, this drug is used to help people who have difficulty falling asleep. This drug might not be right for you if you have other sleep issues, such as not being able to sleep through the night.
While zaleplon is taken at bedtime, some individuals may feel drowsy or less alert about the occurrence of it. Until you know how this drug affects you, do not drive or do something else that may be risky.
Zaleplon takes nearly about 20 to 30 minutes for it to start working. The medications can also be sedative for up to 8 hours.
It works by affecting some parts of the brain and making them feel sleepy and comfortable. It comes in capsule form. Zaleplon is a drug regulated by Schedule IV, meaning that it has the potential for abuse.
Some of the common side effects of zaleplon are drowsiness, dizziness, lightheadedness, lack of coordination, numbness, and tingling in the hands.
Improper storage (exposure to heat, moisture, or sunlight) can reduce its effectiveness or make the medication unsafe to use.
Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.