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Spiramycin

Spiramycin

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By Medicover Hospitals / 25 Jan 2021
Home | Medicine | Spiramycin

What is Spiramycin?

  • Spiramycin is an antibiotic and an antiparasitic macrolide. It is used for the prevention of toxoplasmosis and various other soft tissue infections. The 1.5 mg Spiramycin tablet should be taken on an empty stomach orally. Do not miss any doses and, even though you feel better, complete the full course of treatment. Stopping the medication too early can lead to the return or worsening of the infection. While using this drug, daily monitoring of liver function tests (LFT's) may be needed. During pregnancy, this drug is safe to use. However, if the unborn child has already been tainted, that won't change the nature of the illness. Before taking this drug, tell your doctor if you have any prior history of allergies.
    1. Spiramycin Uses
    2. Spiramycin side effects
    3. Precautions
    4. Dosage
    5. Storage
    6. Spiramycin vs Amoxicillin
    7. Frequently Asked Questions
    8. Citations

    Spiramycin Uses

  • The 1.5mg Spiramycin Tablet is an antibiotic used in pregnant women to treat a bacterial infection known as Toxoplasmosis. It helps to reduce the risk of transmission from the mother to the unborn child of toxoplasma infection. It can rarely be used to treat certain other diseases, too.
  • How to use

  • As directed, take this medication by mouth. This can be taken for food if there is an upset in the stomach. Take each dose at uniformly spaced intervals for the best results. This will ensure and check your blood has a steady dosage level or not. Taking this drug for the prescribed period of time is very important. Without your doctor's permission, do not stop taking it suddenly. Stopping therapy too early can lead to reinfection or chances of getting back the health issues.
  • Side Effects:

    • Skin rash and itching
    • unusual bleeding or bruising
    • Rare
    • Pain at site of injection
    • Rare
    • Bloody stools
    • chest pain
    • Fever
    • Heartburn
    • Irregular heartbeat
    • Mouth Ulcer
    • Nausea
    • Recurrent fainting
    • stomach pain and tenderness
    • vomiting
    • yellow eyes or skin
    • Nausea, vomiting, stomach pain, and diarrhea are the often seen side effects seen with this drug. With the end of therapy, these are typically temporary and subside. If these side effects are not resolved or continue for a longer period of time, contact your doctor.

    Precautions:

  • Pregnancy - In general, the Spiramycin 1.5mg tablet is considered safe to use during pregnancy. Animal studies have shown little to no adverse effects on the developing baby; human studies, however, are minimal.
  • Breastfeeding - No information is available about the use of the 1.5mg Spiramycin tablet during breastfeeding. Consult your physician, please.
  • Driving - Spiramycin 1.5mg tablet normally does not affect your driving performance.
  • Kidney - Safe if Used. Spiramycin 1.5 mg tablet is safe for kidney disease patients to use. No dosage change is recommended for the Spiramycin 1.5mg Tablet.
  • Liver - Consult the physician Limited information on the use of the Spiramycin 1.5mg tablet in patients with liver disease is available. Consult your physician, please.
  • Alcohol - No adverse side effects are caused by drinking alcohol with the Spiramycin 1.5mg tablet.
  • Interactions

  • Tell your doctor if you are taking any prescription or over-the-counter drugs, especially: carbamazepine, cyclosporine, theophylline, triazolam, warfarin, terfenadine, astemizole, cisapride, felodipine (calcium channel blocker). The efficacy of birth control pills can interfere with this medication. Discuss the doctor's use of other birth control methods. Do not start or stop taking any medication without permission from a doctor or pharmacist.
  • Tips

  • To minimize the risk of transmission of toxoplasma infection to your unborn child, your doctor has prescribed a 1.5mg Spiramycin tablet.
  • Do not miss any doses and, even though you feel better, complete the full course of treatment.
  • During your first trimesters of pregnancy, it is safe to use.
  • In order to prevent an upset stomach, take it with food.
  • Diarrhea can occur as a side effect, but when the course is finished, it should stop. If it doesn't stop or you find blood in your stools, tell your doctor.
  • Dosage and administration:

  • For oral dosage (capsules or tablets):
    • - For infection treatment: 1 to 2 grams (3,000,000 to 6,000,000 International Units [IU]) two times a day for adults and adolescents, or three times a day for 500 mg to 1 gram (1,500,000 to 3,000,000 IU). The dosage is 2 to 2.5 grams (6,000,000 to 7,500,000 IU) two times a day for serious infections.
    • - The dosage is dependent on body weight for children weighing 20 kilograms (kg) (44 pounds) or more. The normal/general dosage is 25 mg (75,000 IU) two times a day per kg (11.4 mg per pound) of body weight, or 17 mg (51,000 IU) three times a day per kg (7.7 mg per pound) of body weight (as prescribed by the doctor).
  • For dosage in form of injection:
    • For infection treatment: Every eight hours, adults and adolescents inject 500 mg (1,500,000 IU) steadily into a vein. The dosage is 1 gram (3,000,000 IU) for serious infections, administered slowly into a vein every eight hours.
    • Children- The doctor must assess the use and dosage.
  • For the rectal form of dosage (suppository):
    • For infection treatment: Two or three 750 mg (1,950,000 IU) suppositories a day for adults and children 12 years of age and over. Two or three 500 mg (1,300,000 IU) suppositories a day for children up to 12 years of age.
    • The dosage for newborns is dependent on body weight. The normal dosage is one suppository of 250 mg (650,000 IU) once a day per 5 kg (250 mg suppository per 11 pounds) of body weight.

    Missed Dose:

  • If a dose of this drug is missing, take it as soon as possible. If the time for your next dosage has already arrived, skip the forgotten dose and get back to your normal routine for daily dosing. Do not use duplicate doses.
  • Overdose:

  • If you have overdosed with this medication immediately contact a doctor. Never take 2 doses at the same time, it may result in something very serious.
  • Storage

  • Store the medication at room temperature, away from fire, moisture, and direct light, in a closed bottle. Keep out of the hands of children. Do not keep obsolete/expired medication or medicine no longer needed. Keep away from freezing.
  • Spiramycin vs Amoxicillin :

    Spiramycin
    Amoxicillin
    Molar mass: 843.053 g/mol Molar mass: 365.4 g/mol
    Formula: C43H74N2O14 Formula: C16H19N3O5S
    Spiramycin is a macrolide antibiotic and antiparasitic. Amoxicillin is an antibiotic
    used to treat toxoplasmosis in pregnant and other infections. used to treat a number of bacterial infections. These include middle ear infections, skin infections, and urinary tract infections
    Given orally or through injection Given orally

    Frequently Asked Questions:

    A large range of bacterial infections is treated with spiramycin. This drug is known as an antibiotic with macrolides. It works by preventing bacteria from developing. Only bacterial infections are treated by this antibiotic.
    Every eight hours, adults and adolescents inject 500 mg (1,500,000 IU) steadily into a vein. The dosage is 1 gram (3,000,000 IU) for serious infections, administered slowly into a vein every eight hours. Children- The doctor must assess the use and dosage.
    Yes, Spiramycin is safe to use in pregnancy.
    Spiramycin is a macrolide antibiotic given to Toxoplasma gondii-infected pregnant women. It reduced the infection of the placenta by 60%.
    To treat several forms of infections, spiramycin is used. It is also used in pregnant women to treat toxoplasmosis since this drug reduces the risk that the unborn baby will get the infection. This medication can also be used, as determined by your doctor, for other problems.

    Citations:

  • Spiramycin, https://www.researchgate.net/profile/Nathan_Keller2/publication/13440198_Spiramycin_renaissance/links/0046352124e1e7a053000000.pdf
  • Spiramycin Dosage, https://www.acpjournals.org/doi/abs/10.7326/0003-4819-101-2-202