Sertraline: Uses, Side Effects, Storage and Precautions
Written by Medicover Team and Medically Reviewed by Dr Siva Anoop Yella, Psychiatry
Sertraline is a prescription antidepressant in the selective serotonin reuptake inhibitor (SSRI) class. It is widely used to treat depression, anxiety, and other mood disorders. Known for its tolerability, it helps improve mood, sleep, and energy levels with fewer sedative side effects compared to other antidepressants.
Sertraline (brand name Zoloft) is a medication that increases serotonin levels in the brain to help balance mood and emotional state. It is commonly prescribed for mental health conditions like depression and anxiety disorders.
Sertraline effectively reduces symptoms of several psychiatric conditions, promoting emotional stability and improving daily functioning.
Indications for use of alperide tablet include:
Sertraline works by blocking the reabsorption (reuptake) of serotonin in the brain, increasing its availability. Serotonin is a neurotransmitter associated with mood regulation, anxiety control, and emotional well-being.
Typical Dosage Instructions
Symptoms of overdose may include:
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Get Second OpinionSertraline is approved for use in adults and children aged 6 and older for OCD. It should be used in children only under medical supervision.
Drug Interactions
Supplement & Herbal Interactions
Recommended Storage Temperature
Improper storage may degrade its effectiveness or safety. Avoid storing in bathrooms or near heat sources.
Important Storage Tips
| Sertraline | Fluoxetine |
|---|---|
| Sertraline affects brain chemicals that may be out of whack in people suffering from depression, fear, anxiety, or obsessive-compulsive symptoms. | Fluoxetine is a selective serotonin reuptake inhibitor antidepressant. The medication inhibits the uptake of serotonin by nerve cells. |
| People use Sertraline tablets for treating depression, anxiety, and various mood disorders. | Fluoxetine tablets are used to treat depression, OCD, bulimia nervosa, and panic disorder. |
| Some of the common side effects of Sertraline are: Nausea Diarrhea Constipation Vomiting |
Some of the common side effects of Fluoxetine are: Nervousness Anxiety Difficulty in falling asleep Nausea Diarrhea Dry mouth |

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040-68334455Some of the common side effects of Sertraline include nausea, diarrhea, constipation, vomiting, dry mouth, heartburn, loss of appetite, dizziness, and nervousness. These side effects may vary in intensity and typically subside as the body adjusts to the medication.
Sertraline, like other antidepressants, may help improve your mood and reduce stress. As a result, you might experience better sleep and improved interactions with others as your symptoms of depression or anxiety lessen.
Yes, sertraline is effective for treating anxiety. It may cause an early decrease in anxiety symptoms, often before depressive symptoms improve, making it useful for conditions like generalized anxiety disorder and social anxiety disorder.
Yes, sertraline can be taken once a day, either in the morning or at night. If you experience side effects like nausea, taking it at night may help reduce those symptoms. It’s important to take it at the same time each day.
The maximum dose of sertraline for adults is typically 200 mg per day. This dose is usually reached gradually, starting with a lower dose (e.g., 25–50 mg daily) and increasing based on the individual's response and tolerance under medical supervision. Always follow your doctor’s guidance when adjusting the dosage.
The maximum recommended daily dose of Sertraline for adults is 200 mg, taken once daily. Dosage may be adjusted based on the patient's condition and response, under medical supervision.
No, Sertraline should not be stored in the refrigerator. It should be stored at room temperature, ideally between 20°C to 25°C (68°F to 77°F), away from moisture and heat.
Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.