Seroquel: Uses, Side Effects, Storage and Precautions
Written by Medicover Team and Medically Reviewed by Dr Siva Anoop Yella, Psychiatry
Seroquel, also known by its generic name quetiapine, is an atypical antipsychotic medication commonly prescribed for psychiatric conditions. It is widely used to manage symptoms of schizophrenia, bipolar disorder, and major depressive disorder (MDD). Seroquel helps restore the balance of neurotransmitters in the brain, leading to improved mood, cognition, and behavior.
Seroquel is effective in managing psychotic and mood disorders. It helps reduce symptoms such as hallucinations, mood swings, anxiety, and sleep disturbances, and is also used off-label for certain other psychiatric conditions.
Seroquel may:
Seroquel targets dopamine and serotonin receptors in the brain to regulate neurotransmitter levels. This mechanism stabilizes mood and perception and helps manage psychiatric symptoms.
Seroquel works by:
These actions help balance brain chemicals involved in mood, thinking, and perception. It does not directly affect hormones but can influence hormone levels over time (e.g., prolactin).
Seroquel is available as immediate and extended-release tablets, taken once to three times daily. Dosage starts low and is adjusted gradually under medical supervision for safety and effectiveness.
Typical Dosage Instructions
Always follow the exact dosage as prescribed by your healthcare provider.
If a dose is missed, take it as soon as remembered unless it's close to the next dose. Never double the dose to compensate resume your regular schedule.
An overdose of Seroquel can cause extreme sedation, low blood pressure, irregular heartbeat, or seizures. Immediate medical attention is necessary if an overdose is suspected.
Seek immediate emergency care in case of overdose.
Get a second opinion from trusted experts and makeconfident, informed decisions.
Get Second OpinionCommon side effects of Seroquel include drowsiness, dry mouth, and weight gain. More serious but rare effects may involve heart rhythm problems, suicidal thoughts, or movement disorders.
Consult your doctor if any side effects worsen or if you notice unusual symptoms.
Caution is needed in individuals with heart, liver, thyroid, or seizure conditions. Pregnant women and the elderly should use Seroquel only under strict medical guidance due to potential risks.
Seroquel is approved for use in teens and children for specific conditions, but not for those under 10.Older adults may be more sensitive to side effects such as dizziness or sedation.
Alcohol should be avoided while taking Seroquel, as it increases the risk of drowsiness. The medication can be taken with or without food, though food may help reduce nausea.
Seroquel may interact with drugs like antifungals, antibiotics, and seizure medications. These interactions can affect the drug's effectiveness or increase side effect risks.
Seroquel may interact with:
Always inform your doctor about all medications and supplements you're taking.

Still have questions? Speak with our experts now!
040-68334455This medicine is used to treat a number of psychiatric and mood disorders (such as schizophrenia, bipolar disorder, sudden episodes of mania, or depression associated with bipolar disorder). Seroquel is an antipsychotic medicine (atypical type).
The Food and Drug Administration (FDA) has not approved Seroquel for the treatment of insomnia. It is, however, often administered off-label as a short-term sleep aid due to its sedative effects.
Seroquel is an antipsychotic drug used to treat schizophrenia in adults and children aged 13 and up. Seroquel is an antipsychotic drug used to treat bipolar disorder (manic depression) in adults and children aged 10 and up. Seroquel is also used to manage major depressive disorder in adults when paired with antidepressant medication.
Two recent studies indicate that the antipsychotic medication Seroquel can aid in the treatment of major depression and generalized anxiety disorder. Seroquel has also obtained FDA approval for the treatment of schizophrenia and bipolar disorder (formerly called manic-depressive illness).
Seroquel is a second-generation antipsychotic that also activates the H1 and 2A histamine receptors. Its sedative effects are believed to be due to this, which is why it's used off-label for insomnia.
One of the most common side effects of Seroquel (generic name Seroquel) is that it makes people sleepy. Many physicians prescribe it as a sleeping pill for this purpose, and sometimes at the same dosage as you do — 50 mg.
Seroquel, like other related drugs, can raise the risk of suicidal thoughts or actions in young adults, with the risk being greater in those under the age of 25. Seroquel’s extended-release should not be granted to those under the age of eighteen.
Seroquel is a schizophrenia drug that acts in the brain. It's also known as an atypical antipsychotic or a second-generation antipsychotic (SGA). Seroquel enhances thought, mood, and actions by rebalancing dopamine and serotonin.
The evidence for Seroquel qualifies it as a bimodal mood stabilizer based on its proven efficacy in the treatment of bipolar mania and depression, according to a liberal concept.
Insomnia is treated with Seroquel (quetiapine) and Ambien (zolpidem). Ambien is primarily used to treat insomnia, while Seroquel is used to treat insomnia off-label.
Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.