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By Medicover Hospitals / 04 March 2021
Home | Medicine | plavix

What is Plavix?

  • Plavix belongs to a class of drugs called Antiplatelet Agents, Cardiovascular, Hematologic. Plavix is a prescription medicine used to treat symptoms of an acute coronary syndrome such as stroke, blood clot, or serious heart problems following a heart attack, severe chest pain, or circulatory problems. Plavix may be used on its own or with other medicines.
    1. Plavix Uses
    2. Plavix Side effects
    3. Precautions
    4. Important information
    5. Dosage
    6. Storage
    7. Plavix vs Aspirin
    8. Frequently Asked Questions
    9. Citations

    Plavix Uses:

  • It is used for preventing heart attacks and stroke. Plavix Tablet is an antiplatelet drug or a blood thinner. It works by preventing cells called platelets from sticking together and helps prevent blood from clotting inside the veins and arteries. This helps blood flow freely around your body, preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). Take this medicine on a regular basis and make appropriate lifestyle changes to maximize benefits. It is often prescribed along with a low dose of aspirin, which also helps prevent blood from clotting.
  • How to use Plavix?

  • Read your pharmacist's Medication Guide before you start taking clopidogrel and every time you refill.
  • Take this medicine orally with or without food as directed by your doctor, usually once a day. Take this medicine on a regular basis to make the most of it. To help you remember, take it every day at the same time.
  • The dose and duration of treatment are based on your medical condition and response to treatment. If you are taking this medicine to prevent clots following a stent implant or other procedure, take this medicine with aspirin for several months or years after the procedure as directed by your doctor. For more details and risks of early cessation, consult your doctor. Keep taking this medicine even if you feel good about it. Do not suddenly stop taking this medicine without consulting with your doctor.
  • Do not eat grapefruit or drink grapefruit juice while using this medicine unless your doctor or pharmacist says you can do so safely. Grapefruit might increase the chances of some serious side effects with this medicine. Ask your doctor or pharmacist for further details.
  • Get medical help right away if you have any signs that this medicine doesn't work, such as symptoms of a new heart attack or stroke (such as chest/jaw/left arm pain, shortness of breath, unusual sweating, weakness on one side of the body, difficulty speaking, sudden vision changes, confusion).
  • Plavix Side effects:

    •   Pale Skin
    •   Easy bruising
    •   Purple spots under your skin or in your mouth
    •   Yellowing of your skin or eyes
    •   Jaundice
    •   Fast heartbeats
    •   Shortness of breath
    •   Headache
    •   Fever
    •   Weakness
    •   Feeling tired
    •   Little or no urination
    •   Seizure
    •   Convulsions
    •   Sudden numbness
    •   Weakness
    •   Confusion
    •   Problems with vision or speech
    •   Increased bleeding
    •   Nosebleeds
    •   Headaches
    •   Itching
    •   Bruising


  • Tell your doctor or pharmacist if you are allergic to clopidogrel or similar antiplatelet drugs (thienopyridines such as prasugrel) or if you have any other allergies before you take clopidogrel. This product may have certain inactive ingredients that may cause allergic reactions or other problems. Please speak to your pharmacist for more details.
  • Tell your doctor or pharmacist about your medical history before using this medicine, in particular: bleeding disorders (such as stomach ulcers, brain/eye-bleeding), recent surgery, serious injury/trauma, liver disease, bleeding disorders (such as hemophilia).
  • To reduce the chance of being cut, bruised, or injured, be careful with sharp objects such as razors and nail cutters, and avoid activities such as contact sports.
  • Inform earlier to your doctor or dentist about all the products you use before you have surgery. Your doctor may tell you to stop clopidogrel for at least 5 days before surgery. Do not stop taking clopidogrel without talking to your heart doctor first.
  • This medicine may cause bleeding in the stomach. Daily use of alcohol while taking this medicine may increase your risk of stomach bleeding. Limit alcoholic beverages.
  • This medicine should only be used during pregnancy when specifically asked. Talk to your doctor about the potential risks.
  • It is not identified if this medication is passed into breast milk. Before breastfeeding, check with your doctor.
  • Important information

    • Consume it at the same time every day to get the best results.
    • Plavix Tablet increases the risk of bleeding. Be careful when shaving, using sharp objects, or cutting fingernails or toenails.
    • Do not stop using the medicine without consulting your doctor, as this may increase your chances of having another heart attack or stroke.
    • You may be asked to stop taking Plavix Tablet temporarily if you are scheduled to undergo surgery or dental treatment.


  • Do not share this medicine with others.
  • Laboratory and diagnostic exams such as complete blood count may be performed periodically to monitor progress or to check for side effects. For more details, consult your doctor.
  • Missed Dose

  • If you skip a dose, take it as soon as it is possible. If it is close to the next dose, skip the dose. Take your next dose on a constant schedule.
  • Overdose

  • Never consume more than what is prescribed to you by your doctor.
  • Storage

  • Store away from sunlight and humidity at room temperature. Don't store it in the shower room. Do not flush the medication down the gutter or pour it into the drain unless instructed to do so.
  • Plavix vs Aspirin

    Plavix is an anticoagulant Aspirin is a nonsteroidal anti-inflammatory drug (NSAID).
    Formula: C16H16ClNO2S·HCl Formula: C₉H₈O₄
    Molar mass: 321.82 g/mol Molecular Weight: 180.16 g/mol
    Plavix is an antiplatelet drug used to reduce the risk of heart disease and stroke in those at high risk. Aspirin is used to treat Kawasaki disease, pericarditis, and rheumatic fever.

    Frequently Asked Questions:

    Plavix is a prescription medicine used to treat symptoms of an acute coronary syndrome such as stroke, blood clot, or serious heart problems following a heart attack, severe chest pain, or circulatory problems. Plavix may be used on its own or with other medicines.
    Plavix (clopidogrel bisulfate) and Coumadin (warfarin) are anticoagulants (blood thinners) used to treat patients with the acute coronary syndrome, heart attack (myocardial infarction), peripheral vascular disease, and ischemic stroke.
    Common side effects of Plavix are-
    • Increased bleeding
    • Nosebleeds
    • Headaches
    • Itching
    • Bruising
    Survivors of heart attacks and other heart patients may be more likely to die or have a heart attack within the first three months of stopping Plavix, according to new research. Plavix is an antiplatelet drug.
    Some patients have no side effects, had very good results with Plavix, and even credit it with saving their lives. Others had many different side effects, bruising, uncontrollable bleeding, memory loss, fatigue, swelling of hands and feet, and many more.
    Plavix has been reported to negatively affect the immune system in some patients, impairing the body's ability to fight infection and disease, while other people taking the medication have experienced seizures.
    The combination of clopidogrel and aspirin may reduce the risk of major ischaemic events in patients with a minor ischaemic stroke or a high-risk transient ischaemic attack compared to aspirin alone.
    It may also cause muscle pain, taste disorders, rash, and lower blood pressure. There is an increased risk of cardiovascular events when Plavix is stopped.
    Although two concentrations of clopidogrel tablets (75 mg and 300 mg) are available, the higher-strength tablet is only given as a first dose under certain conditions. You can take clopidogrel at any time of day you find it easier to remember, but take your doses at the same time of day every day.
    Clopidogrel bisulfate rarely causes ageusia (loss of taste). The loss of taste can be complete and can contribute to the loss of appetite and weight. The onset may be delayed. This side effect is reversible when the medication is discontinued.


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