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Mebendazole

Mebendazole

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By Medicover Hospitals / 11 Mar 2021
Home | Medicine | Mebendazole
  • Mebendazole is a prescribed worm medication for Pinworm, Roundworm, Whipworm, and Hookworm. It belongs to the Anthelmintics class of drugs. It is an antiparasitic agent that belongs to the benzimidazole class, which also includes thiabendazole, albendazole, and triclabendazole. Mebendazole, like other benzimidazoles, destroys parasites by blocking glucose uptake and interfering with the role of tubulin, a central protein in parasites.
    1. Mebendazole Uses
    2. Mebendazole Side effects
    3. Precautions
    4. Overdose
    5. Mebendazole vs Ivermectin
    6. Frequently Asked Questions
    7. Citations

    Mebendazole Uses:

  • Mebendazole is a drug that is used to treat a variety of worm infections. Roundworm and whipworm infections are treated with this medication. Pinworm, whipworm, roundworm, and hookworm infections are treated with Emverm. It belongs to the anthelmintic family of drugs. It operates by obliterating the worms.
  • Side Effects:

  • Some of the common side effects of Mebendazole are:
    • Diarrhea
    • Stomach pain
    • Discomfort
    • Swelling
    • Nausea
    • Vomiting
    • Loss of appetite
  • Some of the serious side effects of Mebendazole are:
    • Seizures
    • Rash
    • Hives
    • Shortness of breath
    • Difficulty while breathing
    • Swallowing
    • Fever
    • Sore throat
    • Chills
  • Mebendazole can cause some serious side effects and can lead to some serious health problems. Talk with your doctor if you are having any serious problems.
  • Precautions

  • Before taking Mebendazole talk with your doctor if you are allergic to it or any other medications related to it. The medication may contain some inactive ingredients which can cause some serious allergic reactions or some other serious problems. Before taking the medications talk with your doctor if you are having any medical history such as: Low blood count, Liver disease, intestinal problems and kidney disease. Talk to your doctor if you are taking any prescription and non-prescription medications, vitamins, nutritional supplements and other herbal products.
  • How to use Mebendazole?

  • Mebendazole is available in the form of a chewable tablet. The medication is normally taken twice a day, in the morning and evening, for three days to treat whipworm, roundworm, and hookworm. When treating pinworm, it is usually given as a single (one-time) dose. The drug is typically administered as a single dose. If you are unable to chew the tablet, put it on a spoon and use a dosing syringe to dispense a small amount of water (2 to 3 mL) onto the tablet. The tablet will absorb the water and transform into a soft mass that should be swallowed after 2 minutes.
  • For certain hookworm, roundworm, tapeworm, and whipworm infections, the first dose is 100 mg twice daily for three days.
  • Pinworm infection is treated with a single dose of 100 mg. If necessary, the dose can be repeated in 2 to 3 weeks.
  • Missed dose:

  • If you take mebendazole twice a day and forget to take one dose, take it as soon as you remember. If you recall 4 hours after your dose was meant to be taken, skip the missed dose and proceed with your daily schedule. To make up for a missed dose, do not take a double dose.
  • Overdose:

  • It's unlikely that taking an extra dose of mebendazole can harm you. You can, however, experience side effects such as stomach cramps, being sick, nausea, vomiting and diarrhea. Overdose of a drug can be accidental. If you have taken more than the prescribed tablets there is a chance of getting a harmful effect on your body’s functions.
  • Warnings for Some Serious Health Conditions:

  • Pregnancy & Breastfeeding
  • In animal experiments, negative effects have been observed. Although there have been no reported adverse effects in human pregnancy, it is suggested to delay pinworm treatment until the third trimester if possible.
  • The medication can pass into the breastmilk and can cause some serious side effects to the infants. So, if you are breastfeeding talk to your doctor immediately.
  • Interactions

  • Drug interactions can cause mebendazole to function differently or it can put you at risk for severe adverse effects. Keep a record of all the medications that you use (including prescription and nonprescription medications, as well as herbal products) and share it with your doctor and pharmacist. Do not begin, stop, or adjust the dosage of any medications without first consulting your doctor. The product that can interact with this drug is metronidazole.
  • Storage

  • Direct contact with heat, air and light may damage your medicines. Exposure to medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach.
  • Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).
  • Mebendazole vs Ivermectin :

    Mebendazole
    Ivermectin
    Mebendazole is a prescribed worm medication for Pinworm, Roundworm, Whipworm, and Hookworm. Ivermectin is an anti-parasite medication. It is used for treating infections in the body that are caused by certain parasites.
    Mebendazole is a drug that is used to treat a variety of worm infections. Roundworm and whipworm infections are treated with this medication. Ivermectin is used for intestinal infection which is caused by Strongyloides stercoralis. It is also used for infections that are caused by non-adult forms of Onchocerca Volvulus.
    Some of the common side effects of Mebendazole are:
    • Diarrhea
    • Stomach pain
    • Discomfort
    • Swelling
    Most common side effects of Ivermectin are:
    • Diarrhea
    • Loss of appetite
    • Nausea

    Frequently Asked Questions:

    The medication is normally taken twice a day, in the morning and evening, for three days to treat whipworm, roundworm, and hookworm. When treating pinworm, it is usually given as a single (one-time) dose. The drug is typically administered as a single dose.
    Some of the common side effects of Mebendazole are:
    • Diarrhea
    • Stomach pain
    • Discomfort
    • Swelling
    Mebendazole is a drug that is used to treat a variety of worm infections. Roundworm and whipworm infections are treated with this medication. Pinworm, whipworm, roundworm, and hookworm infections are treated with Emverm.
    Mebendazole, which is present in Vermox, works by stopping worms from consuming sugars that are required for their survival. The worms' energy reserves are depleted as a result, and they die within a few days. The dead worms are then excreted in the stools from the gut.

    Citations:

  • Mebendazole, https://www.sciencedirect.com/science/article/abs/pii/S0010938X09004958
  • Therapy of human hydatid disease with mebendazole and albendazole., https://aac.asm.org/content/37/8/1679.short