Lexapro (escitalipram) is a prescription medication used to treat major depressive disorder and generalized anxiety disorder. It can be used alone or with other medications. Lexapro belongs to a class of drugs called selective serotonin reuptake inhibitors (SSRIs).

Lexapro (escitalopram) Tablet Uses

Lexapro is primarily used to treat depression and anxiety by helping to restore the balance of serotonin in the brain. It can improve energy levels and overall well-being and reduce nervousness.

Conditions Lexapro used to Treat

  • Major depressive disorder (MDD)
  • Generalized anxiety disorder (GAD)

Secondary Uses of Lexapro

  • Obsessive-compulsive disorder (OCD) (off-label)
  • Panic disorder
  • Social anxiety disorder
  • Premenstrual dysphoric disorder (PMDD)

How to Use Lexapro

  • Read Instructions: Read the Medication Guide and Patient Information Leaflet provided by your pharmacist before you start taking Lexapro and each time you get a refill.
  • Dosage: Take this medicine orally with or without food as directed by your doctor, usually once a day in the morning or evening.
  • Liquid Form: If using the liquid form, measure your dose with a special device/spoon, not a household spoon.
  • Start Low: Your doctor may start you at a low dose and gradually increase it to reduce the risk of side effects.
  • Consistency: Take Lexapro at the same time each day for the best effect. Do not increase your dose or take it more frequently than prescribed.
  • Do Not Stop Abruptly: Continue taking this medicine even if you feel well. SStopping suddenly can worsen your condition or cause withdrawal symptoms.

Dosage of Lexapro (escitalopram)

Typical Dosage Instructions

  • Adults (Depression/Anxiety): 10 mg once daily; may increase to 20 mg after a week if needed.
  • Elderly or liver-impaired patients: Start with 5 mg once daily.
  • Taken with or without food, usually in the morning or evening.

What Should I Do If I Miss a Dose?

  • Take it as soon as you remember
  • Skip it if it's close to your next dose
  • Do not double dose

What Happens If an Overdose?

Symptoms of overdose:

  • Dizziness
  • Drowsiness
  • Nausea or vomiting
  • Rapid heartbeat
  • Seizures (in severe cases)

Seek immediate medical attention in case of overdose

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Lexapro Side Effects

Common side effects include:

  • Blurred vision
  • Tunnel vision
  • Eye pain or swelling
  • Seeing halos around lights
  • Racing thoughts
  • Unusual risk-taking behavior
  • Headache
  • Confusion
  • Slurred speech
  • Severe weakness
  • Vomiting
  • Loss of coordination
  • Feeling unsteady
  • Stiff (rigid) muscles
  • High fever
  • Sweating
  • Confusion
  • Fast or uneven heartbeat
  • Tremors
  • Lightheadedness
  • Drowsiness
  • Weakness
  • Sweating
  • Feeling shaky or anxious
  • Sleep problems (insomnia)
  • Dry mouth
  • Nausea
  • Constipation
  • Yawning
  • Weight changes
  • Decreased sex drive
  • Impotence

Precautions and Warnings

Before taking Lexapro, inform your doctor if you have any allergies or medical history of:

  • Bipolar disorder
  • Suicide attempts
  • Liver disease
  • Seizures
  • Bleeding problems
  • Low blood sodium (hyponatremia)
  • Glaucoma

Are There Any Age Restrictions for Using Lexapro?

  • Approved for ages 12 and above for depression
  • Use in children under 12 is not recommended

Alcohol or Food Interactions

Alcohol:

  • Should be avoided - may increase drowsiness and worsen depression or anxiety

Food:

  • No major interactions
  • Can be taken with or without food

Possible Interactions with Other Medications

May Interact With:

  • MAO inhibitors, linezolid (risk of serotonin syndrome)
  • NSAIDs, aspirin, or anticoagulants (increased bleeding risk)
  • Other SSRIs/SNRIs
  • Lithium, tramadol, tryptophan (serotonin syndrome risk)
  • Drugs that prolong QT interval (e.g., antipsychotics, antiarrhythmics)

Supplements and Herbal Products:

  • Avoid St. John's Wort and 5-HTP - can increase serotonin too much

Additional Considerations:

  • The liquid form may contain sugar/aspartame; consult your doctor if you have diabetes or PKU.
  • Older adults may be more sensitive to side effects like QT prolongation, loss of coordination, or bleeding.
  • Children may experience loss of appetite and weight loss.
  • Use during pregnancy should be discussed with your doctor due to potential risks to the unborn child.

How Should Lexapro Be Stored?

Recommended Storage Temperature

  • Store at 20-25°C (68-77°F)
  • Keep in a dry place, away from light and moisture

What Happens If Lexapro Is Not Stored Properly?

  • May degrade or become less effective
  • Avoid exposure to extreme heat, humidity, or direct sunlight

Lexapro vs. Zoloft

Basis Lexapro Zoloft
Generic Name Escitalopram Sertraline
Forms Oral tablet, solution Oral tablet, solution
Strengths Tablet: 5 mg, 10 mg, 20 mg
Solution: 1 mg/mL
Tablet: 25 mg, 50 mg, 100 mg
Solution: 20 mg/mL
Age Range 12 years and older 18 years and older
Dosage Determined by doctor Determined by doctor
Treatment Duration Long-term Long-term
Storage Room temperature, away from heat and moisture Room temperature, away from heat and moisture
Withdrawal Risk Yes Yes

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References

An open-label study of escitalopram (Lexapro®) for the treatment of 'Depression of Alzheimer's disease' (dAD)
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Frequently Asked Questions

Lexapro (escitalopram) is good for the treatment of depression and anxiety. It is generally well-tolerated and has fewer drug interactions than other antidepressants.

Within the first 1-2 weeks, sleep, energy, and appetite can all improve. A significant early indication that the drug is working may be a change in these physical symptoms. It can take up to 6-8 weeks to completely boost the depressed mood and loss of interest in activities.

When taking Lexapro, an individual can gain weight. For various reasons, this can happen. Lexapro increases serotonin, which plays a part in weight management. The drug may increase the appetite directly, or as their depression or anxiety decreases, a person may begin to eat more.

Lexapro is a serotonin reuptake inhibitor that is selective (SSRI). SSRIs function to retain higher serotonin levels in the brain by slowing the reabsorption of serotonin back into nerve cells. Serotonin is a hormone that aids in the control of mood, pleasure, and well-being.

Escitalopram, like Lexapro, is a well-tolerated drug. The medical community may view it as one that slows down the brain's functioning. It is not related to short-term memory loss, and its effects on the brain are not concrete in different study findings.

Researchers claim that some, but not all, antidepressant drugs are known as SSRIs pose a very small but severe heart risk. According to a new study the drugs citalopram and escitalopram can cause heart rhythm disturbances.

Escitalopram can be taken at any time of day as long as you take it at the same time every day. It's best to take it first thing in the morning if you have trouble sleeping.

Lexapro can lead to a disorder of impotence and ejaculation. Celexa and Lexapro both have the ability to cause even more severe side effects. Abnormal bleeding, seizures and vision issues are severe side effects. A black box warning for an increased risk of suicide is required by the FDA on drug labels.

Lexapro (escitalopram) is a more refined version of Celexa (citalopram). Both treat depression and anxiety, but Lexapro may cause fewer side effects and work at lower doses.


Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.

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