Lansoprazole is an orally taken medication that reduces stomach acid and treats conditions like

  • Ulcers
  • GERD
  • Zollinger-Ellison syndrome

Lansoprazole is available in both tablet and capsule forms, depending on the brand and formulation.

Common Forms of Lansoprazole:

  • Delayed-Release Capsules (most common form)
  • Orally Disintegrating Tablets (ODT) - dissolve in the mouth
  • Tablets (less common in some regions)
  • Granules for oral suspension (for children or those who can't swallow pills)

Lansoprazole Uses

Lansoprazole is used to treat specific problems with the stomach and oesophagus (such as acid reflux and ulcers).

It works by reducing the amount of acid the stomach makes. It relieves symptoms such as:

  • Heartburn
  • Difficulty swallowing
  • Persistent coughing.

This medicine helps heal acid damage to the stomach and oesophagus, prevent ulcers, and prevent oesophagal cancer.

Lansoprazole is a class of drugs known as proton pump inhibitors (PPIs).

What is Lansoprazole commonly used for?

  • Gastroesophageal reflux disease (GERD)
  • Peptic ulcers
  • Zollinger-Ellison syndrome
  • Erosive esophagitis

Quick Highlight of Its Benefits or Effectiveness

  • Fast and effective acid reduction
  • Promotes ulcer healing
  • Prevents damage to the stomach lining caused by NSAIDs or excess acid

Conditions Lansoprazole is Used to Treat

  • GERD (acid reflux)
  • Stomach ulcers and duodenal ulcers
  • Erosive esophagitis
  • Zollinger-Ellison syndrome (a rare acid-overproduction disorder)
  • Helicobacter pylori infection (in combination with antibiotics)

How to use?

  • Read the Medication Guide and the Patient Information Leaflet, if available, from your pharmacist before you start taking lansoprazole and every time you refill.
  • Take this medicine by mouth as directed by the doctor, usually once a day, before a meal. The dosage and duration of treatment are based on the medical condition and response to treatment. The dose of children is also based on age and weight.
  • Handle your tablet with your dry hands. Put the tablet on your tongue and let it disintegrate. It takes less than a minute.
  • Swallow the remaining particles with or without water. Do not crush, chew, or break down a tablet or a particle.
  • If you have trouble swallowing the tablet, dissolve it in water and take the mixture by mouth through an oral syringe.
  • Place the tablet in an oral syringe and add the correct amount of water for your dose (4 millilitres for a 15-milligram tablet or 10 millilitres for a 30-milligram tablet).
  • Shake the syringe gently to dissolve the tablet, and swallow the liquid within 15 minutes.
  • To make sure you have taken the total dose, refill the syringe with water (2 millilitres for the 15-milligram tablet or 5 millilitres for the 30-milligram tablet), shake again, and swallow all the liquid. Do not prepare the liquid mixture for later use.

Dosage of Lansoprazole

Typical Dosage Instructions (As Per Doctor's Advice)

  • GERD: 15-30 mg once daily, typically for 4-8 weeks
  • Ulcers: 15-30 mg daily for 4-8 weeks
  • H. pylori eradication: 30 mg twice daily with antibiotics
  • Zollinger-Ellison Syndrome: 60 mg daily (may be increased)

Take before meals, usually in the morning

What Should I Do If I Miss a Dose?

  • Take it as soon as remembered
  • Skip if it's almost time for the next dose
  • Do not double the dose

What Happens If an Overdose?

Symptoms of overdose may include:

  • Confusion
  • Drowsiness
  • Rapid heartbeat
  • Sweating

Seek emergency medical attention if overdose is suspected

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Lansoprazole Side Effects

  • Nervousness
  • Numbness
  • Tingling in your hands and feet
  • Poor muscular coordination
  • Changes in menstruation
  • Low magnesium levels
  • Seizures
  • Dizziness
  • Abnormal or fast heart rate
  • Muscle weakness
  • Spasms in your hands and feet
  • Cramps or muscle aches
  • Spasms of your voice box
  • Serious allergic reactions
  • Rash
  • Throat tightness
  • Trouble breathing
  • Stomach pain
  • Bone fractures
  • Kidney damage
  • Changes in urination
  • Rash on the skin and nose
  • Scaly, red, or purple rash on your body
  • Tiredness
  • Weight loss
  • Blood clots

Serious but Rare Side Effects

  • Vitamin B12 deficiency (with long-term use)
  • Low magnesium levels (muscle cramps, irregular heartbeat)
  • Severe allergic reactions

Report any unusual symptoms to your doctor promptly

Precautions and Warnings

  • Before taking Lansoprazole, inform your doctor or pharmacist about any allergies or medical history, especially liver disease or lupus.
  • Seek immediate medical help if you experience severe symptoms like chest pain or unusual sweating. Discuss any dietary restrictions with your doctor, especially if you have phenylketonuria (PKU).
  • Inform your doctor about all medications and supplements you use, especially before surgery.
  • Discuss with your doctor about the risks of bone fractures associated with long-term use of proton pump inhibitors like Lansoprazole.

Conditions Where Caution Is Needed

  • Long-term use may lead to nutrient deficiencies (magnesium, B12)
  • History of osteoporosis
  • Concurrent use with blood thinners like warfarin

Are There Any Age Restrictions for Using Lansoprazole?

  • Approved for use in children over 1 year for certain conditions
  • Dosage should be adjusted by a pediatrician

Alcohol or Food Interactions

Alcohol:

  • No direct interaction, but alcohol can irritate the stomach lining
  • May worsen the condition being treated

Food:

  • Best taken 30 minutes before meals
  • Delayed-release capsules should not be chewed or crushed

Possible Interactions with Other Medications (Drug Interactions)

May Interact With:

  • Warfarin - may increase bleeding risk
  • Methotrexate - levels may rise
  • Digoxin - absorption may increase
  • Ketoconazole, iron, or calcium supplements - absorption may decrease

Supplements and Herbal Products:

  • Antacids may reduce the effectiveness if taken at the same time
  • Always check with a doctor or pharmacist before combining

How Should Lansoprazole Be Stored?

Recommended Storage Temperature

  • Store at 20-25°C (68-77°F)
  • Protect from moisture and light

What Happens If Lansoprazole Is Not Stored Properly?

  • May lose effectiveness
  • Capsules can degrade in high humidity or heat

Lansoprazole vs Pantoprazole

Lansoprazole Pantoprazole
Molecular Formula: C16H14F3N3O2S Formula: C16H15F2N3O4S
Brand name Prevacid Brand name Protonix
Reduces stomach acid Used as proton pump inhibitors (PPIs)
Lansoprazole is used to treat certain problems with the stomach and esophagus (such as acid reflux, ulcers). Used in the treatment of stomach ulcers, short-term treatment of erosive esophagitis due to gastroesophageal reflux disease.
Molar mass: 369.363 g/mol Molecular Weight: 383.4 g/mol

References

Lansoprazole | Drugs
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Frequently Asked Questions

This medicine works best if it is taken on an empty stomach 30 to 60 minutes before food. Take your medication at regular intervals. Do not take more than directed.

Taking lansoprazole for more than a year may increase your chances of having certain side effects, including bone fractures. Infections of the gut. Vitamin B12 deficiency-symptoms include feeling very tired, a sore and red tongue, ulcers in the mouth, pins, and needles.

Your doctor will tell you how long to take lansoprazole (usually for 4 to 8 weeks). Some people may need to take it longer. It is best to take the lowest effective dose for the shortest time possible.

Check with your doctor right away if you have a change in the frequency of urine or urine, blood in your urine, fever, joint pain, loss of appetite, skin rash, swelling of your body or feet and ankles, unusual tiredness or weakness, or unusual weight gain.

No interactions were identified between lansoprazole and omeprazole. This does not necessarily mean that there are no interactions. Always consult with your health care provider.

It relieves symptoms such as heartburn, difficulty swallowing, and persistent coughing. This medicine helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and can help prevent esophageal cancer. Lansoprazole is a class of drugs known as proton pump inhibitors (PPIs).

PPIs (omeprazole, lansoprazole, esomeprazole, pantoprazole, and others) help reduce the amount of stomach acid produced by the glands in the lining of the stomach. Research published online on 15 February in JAMA Neurology has shown that there may be an association between chronic use of PPIs and an increased risk of dementia.

For people with liver problems: if you have liver problems or a history of liver disease, you may not be able to remove this medicine from your body. If you have severe liver disease, your doctor may reduce your dose of lansoprazole.

Specifically, the risk of clinical depression increased in those taking pantoprazole, lansoprazole, and rabeprazole, while in those taking omeprazole and esomeprazole, only a trend of significance was noted.


Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.

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