What is Synechiae Eye?

Written by Medicover Team and Medically Reviewed by Dr Gargi Apte Jankar , Ophthalmologists


Synechiae Eye is a condition where parts of the eye stick together abnormally; most often, the iris attaches to the cornea or lens. This can interfere with the normal movement of fluid within the eye, leading to increased pressure and potential vision issues.

Also referred to as ocular synechiae, this condition may lead to complications, such as glaucoma, if not treated promptly. Recognising the early signs and receiving prompt eye care can help manage the condition effectively.

Who Gets Eye Synechiae?

Eye synechiae can affect anyone, but is more common in people with:

  • Uveitis (eye inflammation)
  • Eye injuries or trauma
  • Eye infections
  • Previous eye surgeries
  • Glaucoma or high eye pressure

It may also develop as a complication of other eye conditions. Early treatment of underlying issues helps lower the risk.

What are the Types of Synechiae (Eye)?

Synechiae refers to abnormal adhesions or fibrous bands that form between tissues, often due to injury or inflammation. These adhesions can occur in various parts of the body, particularly in the eyes or uterus. Here are the common types of synechiae:

Anterior Synechiae

Anterior synechiae occur when the iris adheres to the cornea. This condition often results from inflammation within the eye and is commonly associated with conditions such as uveitis or trauma. Anterior synechiae can lead to angle-closure glaucoma, a severe form of glaucoma caused by blocked aqueous humour drainage, leading to increased intraocular pressure.

Posterior Synechiae

Posterior synechiae, on the other hand, involves the adhesion of the iris to the lens. This type of synechiae can also result from inflammation, but it is more frequently observed in cases of chronic uveitis. Posterior synechiae can prevent the pupil from dilating properly, causing irregular pupil shape and potentially leading to vision issues.

Partial Synechiae

Adhesions that do not completely obstruct the uterine cavity may lead to less severe symptoms, but they still affect fertility or pregnancy.

Complete Synechiae

When adhesions completely occlude the uterine cavity or significant parts of it, leading to more severe symptoms, such as an absent or significantly reduced menstrual flow (amenorrhea). This is usually linked to serious fertility issues.

Isolated Synechiae

Localized adhesions affect specific areas of the uterus without affecting other regions. Treatment usually depends on the severity and location of these adhesions.


What are the Causes of Synechiae Eye?

The causes of synechiae are varied, often involving inflammation or trauma. Here, we explore some of the most common causes:

  • Trauma or Injury: Physical injury to the eye, such as a blow or chemical burn, can cause inflammation that leads to the formation of synechiae. It can happen after eye surgery, blunt trauma, or even foreign body penetration.
  • Uveitis (Inflammation of the Uveal Tract): Uveitis, which involves inflammation of the iris, ciliary body, and choroid, is a common cause. Inflammation leads to increased protein in the aqueous humour (the fluid in the eye), causing the iris to stick to the cornea or lens.
  • Infections: Eye infections, particularly those involving the uveal tract, can lead to synechiae. Conditions like herpes simplex virus (HSV) keratitis or bacterial endophthalmitis can trigger these adhesions.
  • Chronic or Recurrent Inflammation: Conditions such as juvenile idiopathic arthritis (JIA) or other autoimmune diseases can cause chronic uveitis, resulting in synechiae. These long-term inflammation issues can cause the iris to adhere to surrounding structures.
  • Diseases and Conditions of the Eye: Glaucoma, especially angle-closure glaucoma, and conditions like Fuchs' dystrophy or cataract surgery complications may lead to the development of synechiae.
  • Previous Eye Surgery: Surgery to remove cataracts or treat other eye conditions may occasionally result in the formation of synechiae if there is inflammation or improper healing.

What are the Risk Factors for Synechiae Eye?

  • Ocular Trauma: Physical injury to the eye increases the risk of inflammation and synechiae formation.
  • Previous Eye Surgery: Cataract surgery or trauma from any eye procedure increases the risk of synechiae.
  • Glaucoma: Angle-closure glaucoma, particularly, may lead to increased intraocular pressure and synechiae.
  • Autoimmune Diseases: Conditions like juvenile idiopathic arthritis (JIA) or Behcet's disease can predispose individuals to uveitis and subsequent synechiae.
  • Use of Certain Medications: Long-term use of medications, like prostaglandin analogues for glaucoma, may increase the risk of synechiae.

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What Are the Symptoms of Synechiae Eye?

The symptoms of synechiae can vary depending on the severity and type. Some common symptoms include:

  • Blurred vision
  • Eye pain or discomfort
  • Redness in the eye
  • Sensitivity to light (photophobia)
  • Irregularly shaped pupil

It is essential to note that some individuals may not exhibit noticeable symptoms, making regular eye examinations crucial for early detection and effective management.


How is Synechiae Eye diagnosed?

Diagnosing synechiae involves a comprehensive eye examination conducted by an ophthalmologist. Essential diagnostic tools and techniques include:

  • Slit Lamp Examination: Used to observe iris adhesions to the cornea or lens.
  • Gonioscopy: Checks for adhesions in the angle of the eye (anterior synechiae).
  • Pupil Reactivity: Examines how the pupil reacts to light; synechiae may limit normal movement.
  • Fundus Examination: Identifies any associated retinal or optic nerve changes due to inflammation.
  • Ocular Ultrasonography: Used if there are concerns about complications like cataracts or lens damage.
  • Anterior Chamber Assessment: Look for signs of inflammation and fluid accumulation in the anterior chamber.
  • Tonometry: Measures eye pressure, as synechiae can affect intraocular pressure in cases of glaucoma.

What are the Treatment Options for Synechiae Eye?

Treatment for ocular synechiae aims to alleviate symptoms, prevent complications, and address the underlying cause of the condition. Treatment options vary based on the type and severity of synechiae.

  • Anti-inflammatory Medications:
      • Corticosteroids (eye drops or oral) to reduce inflammation.
      • Non-steroidal anti-inflammatory drugs (NSAIDs) may be used in some cases.
    • Mydriatic Agents: Atropine or homatropine eye drops to dilate the pupil and prevent further adhesions.
    • Laser Therapy: Laser iridotomy or laser synechiolysis may be used to break existing ocular synechiae, especially in cases where the adhesions cause pupil distortion.
  • Surgical Intervention
    • In severe cases, surgical removal of the synechiae or iris repair may be needed.
    • Treatment of Underlying Conditions: Managing the root cause, such as treating uveitis or infections, can help prevent the recurrence of synechiae.
  • Glaucoma Treatment: Ocular synechiae can lead to increased intraocular pressure (glaucoma); therefore, medications or surgery to reduce eye pressure may be necessary.

When to See a Doctor for Synechiae Eye?

You should see a doctor if you notice:

  • Blurred or reduced vision
  • Eye pain or discomfort
  • Sensitivity to light
  • Redness or visible changes in the eye
  • A history of eye injury or inflammation

Early treatment can prevent complications, such as glaucoma, and protect your vision. Don't delay if you experience any unusual eye symptoms.


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What is the Prevention of Synechiae Eye?

  • Prompt Treatment of Eye Infections: Early management of eye infections (e.g., uveitis, herpes simplex) can reduce the risk of synechiae.
  • Regular Eye Check-ups: Periodic eye exams, especially for individuals with a history of ocular trauma or uveitis, help catch issues early.
  • Protective Eyewear: Wearing sunglasses or protective goggles can prevent trauma or irritation that may trigger ocular synechiae formation.
  • Controlled Glaucoma Treatment: Managing glaucoma appropriately through medications can reduce the risk of iris involvement and synechiae.
  • Post-Surgical Care: Adhering to post-operative instructions after eye surgeries (e.g., cataract surgery) can prevent complications that may lead to ocular synechiae.
  • Managing Autoimmune Conditions: Controlling systemic conditions that predispose to uveitis, such as juvenile arthritis, reduces the likelihood of developing ocular synechiae.

What are the Potential Complications of Ocular Synechiae (Eye)?

If not treated, ocular synechiae can lead to serious problems, including:

  • Glaucoma (increased eye pressure)
  • Vision loss or blurred vision
  • Permanent pupil irregularities
  • Chronic eye pain or discomfort
  • Difficulty with eye exams or surgery

Timely diagnosis and treatment are key to preventing long-term damage.


Our Experience in Treating Ocular Synechiae

At Medicover Hospitals, we treat ocular synechiae with care and expertise. Our eye specialists utilise modern tools to identify problems early and treat them gently. We focus on reducing pressure, easing discomfort, and preventing vision loss. Each patient receives a personalised treatment plan tailored to their specific needs. With our skilled team and 24/7 support, we work to protect your sight and restore eye health.


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Frequently Asked Questions

The outlook depends on severity and underlying cause. With early treatment and monitoring, vision can often be preserved. However, untreated synechiae can lead to complications like glaucoma or permanent vision loss.

Synechiae can sometimes be broken or managed with medications or surgery, but complete reversal isn't always possible. The goal is to prevent progression and complications like elevated intraocular pressure.

Iris processes are normal anatomical strands extending from the iris to the trabecular meshwork, whereas synechiae are abnormal adhesions of the iris to the lens (posterior) or cornea (anterior) often due to inflammation.

Prevention includes early treatment of eye inflammation, use of mydriatic drops like atropine to keep the pupil mobile, and controlling underlying diseases such as uveitis or trauma that increase synechiae risk.

Synechiae may be partially reversible if treated early, especially with pupil-dilating drops. Long-standing or extensive adhesions often become permanent and may require surgical intervention for vision preservation.

Treatment includes corticosteroids to reduce inflammation and mydriatics like atropine to break or prevent adhesions. Monitoring intraocular pressure and managing complications like glaucoma are also key in uveitis cases.

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