Scleredema: Symptoms and Care

Scleredema is a rare skin condition that affects the body's connective tissues, causing the skin to become thick and hardened. This can lead to decreased flexibility and mobility in the affected areas. The primary impact of scleredema on health is the potential impairment of movement and discomfort due to the tightness and stiffness of the skin. Managing this condition can be challenging, but early detection and appropriate care can help improve the quality of life for individuals living with scleredema.

Symptoms of Scleredema

Scleredema typically presents with symptoms that primarily affect the skin and underlying tissues.

  • Thickened, hardened skin
  • Limited joint mobility
  • Tightness or stiffness in the affected areas
  • Redness or discoloration of the skin
  • Swelling, especially in the face, neck, or upper back area

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Causes of Scleredema

Scleredema is primarily caused by the excessive accumulation of collagen in the skin's connective tissue, leading to thickening and hardening of the affected areas.


Types of Scleredema

Scleredema typically presents in different forms, each with its distinct characteristics and symptoms, influencing its diagnosis and management.

  • Localized Scleredema: Characterized by thickened skin patches usually on the upper body.
  • Generalized Scleredema: Affects larger areas of the body, often following an infection or illness.
  • Diabetic Scleredema: Associated with diabetes and manifests as skin thickening, often on the upper back and neck.
  • Scleredema Adultorum of Buschke: Rare form affecting adults, leading to skin thickening mainly on the upper body.
  • Scleredema Pediatricorum: Occurs in children and is characterized by skin thickening, especially on the face and neck.

Risk Factors

Scleredema risk factors include conditions such as diabetes, infections, and certain medications that can contribute to the development of this rare skin disorder.

  • Diabetes
  • Infections
  • Autoimmune diseases
  • Obesity
  • Radiation therapy

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Diagnosis of Scleredema

Scleredema is typically diagnosed through a combination of physical examination and medical history assessment.

  • Physical examination
  • Skin biopsy
  • Imaging tests such as MRI or ultrasound

Treatment for Scleredema

Scleredema is typically managed through a combination of treatment modalities aimed at improving skin flexibility and reducing symptoms.

  • Physical therapy: Physical therapy can help improve range of motion and reduce stiffness in affected areas of the body in individuals with Scleredema.
  • Topical treatments: Topical treatments such as moisturizers and corticosteroid creams can help manage skin symptoms and improve overall skin health.
  • Phototherapy: Phototherapy, using ultraviolet light, may be beneficial in reducing skin thickening and improving skin flexibility in some patients with Scleredema.
  • Immunosuppressive medications: In severe cases, immunosuppressive medications may be prescribed to help reduce inflammation and slow down the progression of Scleredema.
  • Symptom management: Symptom management strategies such as pain relief medications, compression garments, and lifestyle modifications can help individuals cope with the symptoms of Scleredema and improve their quality of life.
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Frequently Asked Questions

What is Scleredema?

Scleredema is a rare skin condition characterized by thickening and hardening of the skin, usually on the upper back, neck, and shoulders.

What are the symptoms of Scleredema?

Symptoms of Scleredema may include skin tightening, limited joint mobility, difficulty moving affected areas, and sometimes pain.

What causes Scleredema?

The exact cause of Scleredema is unknown, but it is believed to be related to an overproduction of collagen in the skin following a triggering event like an infection or trauma.

How is Scleredema diagnosed?

Diagnosis of Scleredema is typically based on physical examination, medical history, and sometimes skin biopsies to rule out other conditions with similar symptoms.

Is there a cure for Scleredema?

There is no cure for Scleredema, but treatment focuses on managing symptoms such as physical therapy, moisturizing creams, and occasionally medications to help reduce inflammation.

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