Endometrioid Ovarian Cancer - Causes and Symptoms

Endometrioid ovarian cancer is a type of cancer that originates in the cells of the ovaries. Unlike other types of ovarian cancer, endometrioid ovarian cancer is specifically linked to the presence of endometrial tissue in the ovaries. This type of cancer is believed to develop when endometrial cells from the lining of the uterus travel to the ovaries and start growing uncontrollably.

The exact cause of this migration is not fully understood, but several factors may contribute to the development of endometrioid ovarian cancer. While the precise mechanisms are complex, researchers suspect that hormonal imbalances, genetic predisposition, and inflammation may play a role in the initiation and progression of this type of cancer. Understanding the underlying causes of endomet.

What Are the Symptoms of Endometrioid Ovarian Cancer

Endometrioid ovarian cancer can present with various symptoms that may include pelvic pain, bloating, changes in bowel habits, frequent urination, fatigue, and abnormal vaginal bleeding. Some patients may also experience weight loss, back pain, and discomfort during sexual intercourse. It is essential to seek medical evaluation if you notice persistent or worsening symptoms, as early detection can lead to better treatment outcomes. Your healthcare provider can perform tests to determine the cause of your symptoms and provide appropriate care tailored to your needs.

Persistent abdominal or pelvic pain, especially during menstruation, intercourse, or bowel movements, can be a symptom of endometrioid ovarian cancer.
Unexplained bloating, feeling full quickly after eating, or changes in bowel habits like constipation or diarrhea may indicate endometrioid ovarian cancer.
Fatigue, weakness, or unexplained weight loss can be nonspecific symptoms of various conditions, including endometrioid ovarian cancer.
Irregular menstrual cycles, heavy periods, or abnormal vaginal bleeding, particularly post-menopause, should raise suspicion for endometrioid ovarian cancer.
Pelvic pressure, frequent urination, or difficulty emptying the bladder could be signs of endometrioid ovarian cancer and warrant further evaluation.

Get a second opinion from trusted experts and makeconfident, informed decisions.

Get Second Opinion

Causes of Endometrioid Ovarian Cancer

This tissue can implant itself on the ovaries, leading to the development of cancerous cells. Other contributing factors include genetic predisposition, hormonal imbalances, and environmental influences. Studies suggest that estrogen plays a significant role in the development of endometrioid ovarian cancer, as it promotes the growth of endometrial cells. Additionally, factors like age, obesity, and reproductive history can also increase the risk of developing this type of ovarian cancer.

Genetic mutations, such as in the BRCA1 and BRCA2 genes, can increase the risk of developing endometrioid ovarian cancer.
Prolonged exposure to estrogen without the counterbalancing effect of progesterone may contribute to the development of endometrioid ovarian cancer.
Obesity is a known risk factor for endometrioid ovarian cancer, as excess body fat can lead to hormonal imbalances that promote cancer growth.
Women who have never been pregnant or who have had infertility issues may have a higher risk of developing endometrioid ovarian cancer.
A family history of ovarian, breast, or colorectal cancer can increase the likelihood of developing endometrioid ovarian cancer.

Types Of Endometrioid Ovarian Cancer

There are two main types of endometrioid ovarian cancer based on molecular characteristics: Type I, which is associated with endometriosis and typically has a favorable prognosis, and Type II, which is more aggressive and not linked to endometriosis. These subtypes may have distinct genetic mutations and respond differently to treatment. Understanding these variations is crucial for accurate diagnosis and personalized management of endometrioid ovarian cancer patients.

Endometrioid ovarian cancer is a subtype of epithelial ovarian cancer.
It is characterized by tumor cells that resemble the tissue lining the uterus.
The most common type of ovarian cancer, accounting for about 20% of cases.
Usually occurs in women during their pre or postmenopausal years.
Associated with endometriosis, a condition where tissue similar to the lining of the uterus grows outside the uterus.
Can present with symptoms such as pelvic pain, bloating, and abnormal bleeding.
Treatment typically involves surgery, chemotherapy, and sometimes hormone therapy.
Prognosis varies depending on the stage at diagnosis and response to treatment.

Risk Factors

Endometrioid ovarian cancer risk factors include age, with higher incidence in women over 50, a family history of ovarian, breast, or colorectal cancer, endometriosis, never having been pregnant, hormone replacement therapy, obesity, and Lynch syndrome. Additionally, genetic mutations like BRCA1 and BRCA2 can predispose individuals to this type of cancer. Understanding these risk factors can help in early detection and proactive management of endometrioid ovarian cancer.

Age: Being over the age of 50 is a significant risk factor for developing endometrioid ovarian cancer.
Family History: A family history of ovarian, breast, or colorectal cancer increases the risk of endometrioid ovarian cancer.
Hormone Replacement Therapy: Prolonged use of estrogen without progesterone in hormone replacement therapy can elevate the risk of endometrioid ovarian cancer.
Endometriosis: Women with a history of endometriosis are at a higher risk of developing endometrioid ovarian cancer.
Obesity: Being overweight or obese is associated with an increased risk of endometrioid ovarian cancer due to hormonal changes.

Your health is everything - prioritize your well-being today.

Schedule Your Appointment

Diagnosis of Endometrioid Ovarian Cancer

Initially, a thorough physical examination and medical history review are conducted. Imaging tests such as ultrasounds or CT scans may be performed to visualize the ovaries and surrounding tissues. A definitive diagnosis often requires a biopsy, where a tissue sample is collected and analyzed under a microscope to identify cancerous cells. Additionally, blood tests may be done to check for specific markers associated with ovarian cancer. These diagnostic methods, when used in conjunction, can help healthcare providers accurately diagnose endometrioid ovarian cancer and develop an appropriate treatment plan.

Pelvic exam and ultrasound imaging help detect abnormalities in the ovaries.
Blood tests for CA-125 levels may be elevated in cases of endometrioid ovarian cancer.
Imaging tests like CT scans or MRI are used to determine the extent of the cancer.
Biopsy of suspicious ovarian tissue confirms the presence of endometrioid ovarian cancer.
Surgical exploration through laparoscopy or laparotomy allows for direct visualization and tissue sampling.

Treatment for Endometrioid Ovarian Cancer

Treatment options for Endometrioid Ovarian Cancer typically involve a multidisciplinary approach to address the disease comprehensively. The primary treatment is usually surgery to remove the affected ovary or ovaries, along with any surrounding tissues or lymph nodes if necessary. Following surgery, chemotherapy may be recommended to target any remaining cancer cells and reduce the risk of recurrence.

Hormonal therapy, targeted therapy, or radiation therapy might also be considered depending on the individual's specific case and overall health. The treatment plan is tailored to each patient to achieve the best possible outcomes and improve quality of life. Regular follow-up care and monitoring are essential to track progress and manage any potential side effects.

Surgery is often the primary treatment and may involve removing the affected ovary or ovaries, the uterus, fallopian tubes, and nearby lymph nodes. Chemotherapy using powerful drugs to kill cancer cells may be recommended after surgery to target any remaining cancer cells in the body.

Targeted therapy, which specifically targets cancer cells while minimizing damage to healthy cells, may also be used in some cases to treat Endometrioid Ovarian Cancer. Hormone therapy, which alters hormone levels in the body to slow the growth of cancer cells, is another treatment option that may be considered depending on the specific characteristics of the cancer.

Find Our Specialists

Book Doctor Appointment