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The Antistreptolysin O (ASO) test checks the level of ASO antibodies in the blood, helping to find out if you had a recent streptococcal infection. It is mainly used to diagnose conditions like rheumatic fever or kidney problems caused by strep bacteria. The test is a simple blood draw, and the cost can vary depending on the hospital and city. It is quite safe, with minor risks like slight pain or bruising where the blood is taken.
What is the Antistreptolysin O (ASO) Test?
The ASO test measures the level of antistreptolysin antibodies in the bloodstream. These antibodies are produced by the immune system when it encounters streptolysin O toxin created by group A Streptococcus (GAS) bacteria. The production of these antibodies is a response to the GAS bacteria and helps the body fight against the infection.
Alternative Names: ASLO; ASO titer
Antistreptolysin O (ASO) Titer Test Measure
- The ASO titer test is used to measure the amount of antibodies produced by the body in response to a streptococcal infection.
- Increased levels of ASO antibodies indicate a recent or ongoing streptococcal infection.
- This test is valuable in the diagnosis of streptococcal infections like strep throat or scarlet fever.
- By monitoring ASO levels, doctors can help prevent complications such as rheumatic fever or glomerulonephritis, which can occur if a streptococcal infection is not treated.
- ASO titers are typically at their highest point around three to six weeks after the infection begins and then gradually decrease over time.
Why is the ASO Test Done?
The ASO test, also known as the antistreptolysin O titer test, evaluates the body's antibodies in response to the group A Streptococcus (GAS) bacteria.
However, a strep infection may sometimes not show symptoms and could result in post-streptococcal complications. To prevent such complications, doctors perform the ASO test.
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Get Second OpinionWhen is the Antistreptolysin O (ASO) Test Needed?
If you show symptoms of post-streptococcal complications, such as
- Rheumatic fever,
- Glomerulonephritis, or bacterial endocarditis, your physician may suggest an ASO test.
Medical professionals use the antistreptolysin O titer test to evaluate your body's levels of antistreptolysin antibodies, which can help diagnose whether you are experiencing post-streptococcal complications.
How is the Antistreptolysin O (ASO) Test Performed?
The healthcare provider may instruct you to fast for six hours before taking the ASO test. The procedure involves drawing blood from your inner arm vein with a fine needle, and the blood is then collected in a tube by the lab technician. The tube will be sent to the laboratory for examination.
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What is the Usual Range of Antistreptolysin O (ASO)?
The normal ASO test range for adults is below 200, while for children under five years, it is below 100. If your results exceed these levels, you may have a post-streptococcal complication.
Sometimes, even if your ASO test results are expected, your physician may recommend a follow-up test (second test) if you show symptoms of a post-streptococcal complication.
How Do I Understand My ASO Test Results?
An abnormal or positive ASO titer test result indicates a recent strep infection, even if you did not experience symptoms. Here's what it means:
- High ASO levels: This indicates a recent or ongoing infection, like strep throat or scarlet fever.
- Timeline: ASO levels are usually highest around 3 to 6 weeks after the infection starts, and then they start decreasing.
- Complications: If left untreated, strep infections can lead to complications like rheumatic fever or glomerulonephritis. High ASO levels can signal a risk of these issues.
- No symptoms: Even without symptoms, a high ASO level can show that the infection occurred.
- Follow-up: Doctors use the ASO test to monitor and prevent long-term issues. A follow-up test may be needed to check if ASO levels are decreasing, showing that the infection is resolving.
Always consult your doctor for further steps if your results are abnormal.
Are There Any Risks or Side Effects of the Antistreptolysin O (ASO) Test?
Vein and artery sizes vary between individuals and even between different sides of the body. This can sometimes make it more difficult to draw blood from some people than others. The risks associated with blood draws are minimal but may include:
- Excessive bleeding at the needle insertion site
- Fainting or feeling lightheaded
- Hematoma (blood collecting under the skin)
- Infection (a slight risk anytime the skin is broken)
For ASO titer treatment, if the ASO test is positive, treatment may involve antibiotics or other medications to address any complications.
Is it Necessary to Fast Before an ASO Blood Test?
Before undergoing the antistreptolysin O titer test, the physician may advise you to fast for six hours to provide a blood sample.
Who Should Take the ASO Test?
The ASO test is typically recommended for individuals who have symptoms of a recent streptococcal infection or those at risk for post-streptococcal complications. These groups include:
- Children and teenagers: Especially those who have had or are at risk for strep throat, scarlet fever, or rheumatic fever.
- Adults with a history of recurrent throat infections: Especially if untreated or if complications like rheumatic fever are suspected.
- People with unexplained symptoms of strep infection: Even if they didn't have obvious symptoms, the test may be recommended to detect past infections.
- Individuals with kidney issues: ASO levels can help in monitoring conditions like glomerulonephritis after a strep infection.
How Should I Prepare for the Antistreptolysin O (ASO) Test?
There is no special preparation needed for the ASO test. However, it's important to:
- Avoid fasting: You don't need to fast before this test.
- Inform your doctor about medications: Certain medications or conditions may affect the test results, so always tell your healthcare provider about any medications you are taking.
- Hydrate: Drink water before the test to make it easier to collect a sample if needed.
What Type of Sample is Collected for the ASO Test and How?
The ASO test requires a blood sample. Here's how it's collected:
- Blood collection: A healthcare professional will clean the area, usually on your arm, and use a needle to draw blood from a vein.
- The process takes just a few minutes and is generally well-tolerated.
- The sample is then sent to the lab for analysis to measure the ASO levels in your blood.
Are There Other Ways to Collect the Sample for the ASO Test?
For the ASO test, blood collection is the standard method. There are no alternative methods, such as urine or swab tests, for this particular test. However, in some cases, a throat swab may be used to test for strep bacteria directly, but this is separate from the ASO test and is not used to measure antibody levels.
How Long Does the ASO Test Take?
- Sample collection time: The ASO test requires a simple blood draw, which typically takes about 5 to 10 minutes.
- Results timeline: After the blood sample is sent to the lab, results are generally available within 12 to 24 hours, depending on the lab's processing time.
When Will I Get My ASO Test Results?
- Typical turnaround time: You will usually receive your ASO test results within 12 to 24 hours, depending on the lab's processing time.
- How results are delivered: The results are typically sent directly to you via WhatsApp or provided as a printed copy.
- Once you have received your results, your doctor will go over them with you and guide you on the next steps, such as treatment or further tests, if needed.
What Should I Do After Getting My Antistreptolysin O (ASO) Test Results?
- Follow-up: After receiving your ASO test results, it's important to follow up with your doctor.
- Next steps: Based on your results, your doctor may suggest further testing, or if your ASO levels are elevated, treatment may be recommended to prevent complications like rheumatic fever or glomerulonephritis.
Is the ASO Test Painful?
- The ASO test involves a simple blood draw, which is generally not painful.
- Mild discomfort: You may feel a slight pinch or sting when the needle is inserted, but this discomfort is temporary.
What are the Factors Affecting the ASO Test Cost?
- Lab type: The cost may vary depending on whether the test is done in a government or private lab.
- Location: Cost can vary based on the city or region.
- Test method: Different testing methods or technologies may influence the cost.
- Additional services: Consultation fees, follow-up visits, or extra tests may increase the overall cost.
How Much Does the ASO Test Cost in India?
- Approximate cost: The ASO test typically costs around Rs. 500.
- Price variations: The cost may vary depending on the lab, city, or location where the test is conducted.
ASO Test Price in Different Cities Across India
| City | Price |
| Hyderabad | Rs. 500 |
| Chandanagar | Rs. 500 |
| Karimnagar | Rs. 500 |
| Nizamabad | Rs. 500 |
| Warangal | Rs. 500 |
| Vizag | Rs. 500 |
| Srikakulam | Rs. 500 |
| Kakinada | Rs. 500 |
| Kurnool | Rs. 500 |
| Nellore | Rs. 500 |
| Navi Mumbai | Rs. 500 |
| Nashik | Rs. 500 |
| Chhatrapati Sambhaji Nagar | Rs. 500 |
| Pune | Rs. 500 |
| Sangamner | Rs. 500 |
| Bengaluru | Rs. 500 |
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Frequently Asked Questions
The ASO test is not typically used to diagnose strep throat, as it is a blood test, not a throat swab test.
The ASO test is not typically used to monitor the effectiveness of streptococcal treatment, as ASO levels may remain elevated even after successful treatment.
Although the risks associated with the ASO test are very rare, they can include bleeding or bruising at the site where the blood is drawn and infection.
Yes, ASO levels can vary from person to person based on factors such as age, sex, and general health.
ASO titers may not be increased in cases involving cutaneous or renal sequelae but are elevated in 85% of individuals with rheumatic fever.
ASO treatment, in comparison to AAV treatment, does not result in a permanent cure and requires regular drug administration to the patient to keep the toxicity levels low.
The cost of an ASO test is approximately Rs. 500/-
