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The Alpha-Fetoprotein (AFP) test is used to identify liver disorders, certain cancers, and pregnancy-related conditions. This quick and simple blood test varies in cost depending on the lab and city. Knowing the normal range is essential for accurate health assessment. The procedure is generally safe, with minimal risks such as slight discomfort during sample collection.
What is Alpha-Fetoprotein (AFP) Test?
The Alpha-Fetoprotein (AFP) Test measures the level of AFP, a protein produced in the liver, in the blood. It is commonly used to aid in diagnosing liver, ovarian, and testicular cancers and to monitor cancer treatment effectiveness. However, high AFP levels may also result from non-cancerous conditions like liver diseases, and normal levels do not always rule out cancer.
Why is the Alpha-Fetoprotein (AFP)Test Done?
An AFP tumor marker test is done to diagnose and treat cancers of the liver, ovaries, or testicles that produce high amounts of AFP. It is used to:
- Help confirm or rule out cancer, when used with other examinations and testing.
- Predict the behavior of cancer throughout time.
- Keep track of the cancer therapy. AFP levels frequently rise when cancer develops and fall when treatment is effective.
- Examine whether cancer has returned after treatment.
In some cases, the results of the AFP tumor marker test may be used to guide treatment decisions for certain forms of cancer. If you have chronic (long-term) hepatitis or cirrhosis of the liver, the test may also be performed to monitor your health. These conditions aren't cancer, but they raise the chances of developing it.
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Get Second OpinionWho Should Take the Alpha-Fetoprotein (AFP) Test?
One may require an AFP tumor marker test if you have the following:
- A physical exam and other tests indicate you may have liver, ovarian, or testicular cancer.
- You are currently undergoing treatment for cancer that causes high AFP levels. Monitoring the AFP test might reveal how effective the treatment is.
- Individuals have completed cancer therapy, which increased the AFP level. You may require an AFP tumor marker test from time to time to determine whether your cancer has returned.
You are more likely to get liver cancer with chronic hepatitis or cirrhosis. A very high AFP level or a fast increase may indicate liver cancer early. Most medical authorities do not recommend testing AFP levels in these disorders for screening for cancer. Even so, some doctors may still employ an AFP tumor marker test in combination with other tests to screen for liver cancer.
How is the Alpha-Fetoprotein (AFP)Test Performed?
A healthcare professional will use a tiny needle to take blood from a vein in the arm. After the insertion of the needle, a little amount of blood will be collected in a test tube or vial. When the needle goes in or out, you may feel a slight sting. This usually takes under five minutes.
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How Should I Prepare for the Alpha-Fetoprotein (AFP) Test?
No specific preparation is needed for the AFP Test. However, inform your doctor about any ongoing medications.
How Do I Understand My Alpha-Fetoprotein (AFP) Test Results?
If you haven't had a cancer diagnosis, test results show:
- High levels of AFP may indicate liver,ovarian, or testicular cancer. However, having a high AFP level does not imply that you have or will get cancer. High AFP levels can also be caused by liver damage and non-cancerous liver disorders. High levels of AFP may be a marker of other malignancies, such as lymphoma or lung cancer, less frequently. The provider will establish a diagnosis based on the medical history and other test results.
- Normal AFP levels indicate that you are less likely to get cancer that causes high AFP levels. A normal test result, on the other hand, does not rule out cancer because some individuals with these cancers have normal AFP levels.
If you are being treated for cancer that has caused an increase in your AFP levels, you may be tested multiple times during your therapy. The doctor will review the previous AFP test results to determine how the levels have changed. If the results indicate:
- Rising AFP Levels: If your AFP levels are rising, it could indicate that the treatment isn't working.
- Falling AFP Levels: If your AFP levels are falling, it could indicate that the treatment is working.
- Stable AFP Levels: If your AFP levels have remained constant, it may indicate that the condition is stable and has not progressed.
When is the Alpha-Fetoprotein (AFP) Test Needed?
Alpha-Fetoprotein (AFP) test is recommended for several reasons, including:
- Liver Disease: To screen for liver diseases, such as cirrhosis or hepatitis.
- Liver Cancer: To help detect liver cancer (hepatocellular carcinoma) in people with chronic liver conditions.
- Cancer Detection: If you have certain types of cancer, such as ovarian or testicular cancer, to monitor the presence of AFP.
- Pregnancy Complications: To screen for birth defects, such as neural tube defects, in pregnant women, especially in the second trimester.
- Family History: If you have a family history of liver disease or cancer, your doctor may recommend this test as a preventive measure.
What Type of Sample is Collected for the Alpha-Fetoprotein (AFP) Test and How?
For the Alpha-Fetoprotein (AFP) test, a blood sample is collected.
How Long Does the Alpha-Fetoprotein (AFP) Test Take?
The Alpha-Fetoprotein (AFP) test involves a quick blood draw, which typically takes just 5-10 minutes. The entire process is brief and minimally disruptive.
When Will I Get My Alpha-Fetoprotein (AFP) Test Results?
You will usually receive your Alpha-Fetoprotein (AFP) test results within 12 to 24 hours, depending on the lab's processing time. Reports will be sent directly to you via WhatsApp or as a printed copy. Once you have your results, our doctor will explain them and guide you on the next steps, if needed.
What Should I Do After Getting My Alpha-Fetoprotein (AFP) Test Results?
After receiving your AFP test results:
- If Normal: You may not need any immediate follow-up. Continue with routine health screenings as advised by your doctor.
- If Abnormal: Your doctor may recommend further diagnostic tests or refer you to a specialist for treatment options, such as imaging tests, biopsy, or surgery if necessary.
Are There Any Risks or Side Effects of the Alpha-Fetoprotein (AFP) Test?
The Alpha-Fetoprotein (AFP) test is very safe. It involves a simple blood draw and carries minimal risks, such as mild bruising, swelling, or discomfort at the needle insertion site. Serious side effects are extremely rare.
Is the Alpha-Fetoprotein (AFP) Test Painful?
The Alpha-Fetoprotein (AFP) test is generally not painful. You may feel a brief pinch or sting when the needle is inserted, but the discomfort is minimal and only lasts for a few seconds.
How Much Does the Alpha-Fetoprotein (AFP) Test Cost in India?
The AFP test cost in India varies depending on the location and diagnostic center, typically ranging between Rs.500 to Rs.2000.
- Discuss the Alpha-Fetoprotein (AFP) Test:Procedure and Results with your healthcare provider to understand its implications for your health.
If you have a long-term liver disease that isn't cancer, you may require additional testing to rule out liver cancer if the AFP levels suddenly rise or are extremely high. Discuss with the health provider the implications of the test results for your health.
Alpha-Fetoprotein (AFP) Test Price in Different Cities Across India
| City | Price |
| Hyderabad | Rs.500 to Rs.2000 |
| Chandanagar | Rs.500 to Rs.2000 |
| Karimnagar | Rs.500 to Rs.2000 |
| Nizamabad | Rs.500 to Rs.2000 |
| Warangal | Rs.500 to Rs.2000 |
| Vizag | Rs.500 to Rs.2000 |
| Srikakulam | Rs.500 to Rs.2000 |
| Kakinada | Rs.500 to Rs.2000 |
| Kurnool | Rs.500 to Rs.2000 |
| Nellore | Rs.500 to Rs.2000 |
| Vizianagaram | Rs.500 to Rs.2000 |
| Navi Mumbai | Rs.500 to Rs.2000 |
| Nashik | Rs.500 to Rs.2000 |
| Chh. Sambhajinagar | Rs.500 to Rs.2000 |
| Pune | Rs.500 to Rs.2000 |
| Sangamner | Rs.500 to Rs.2000 |
| Bangalore | Rs.500 to Rs.2000 |
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Frequently Asked Questions
The frequency of the AFP test depends on the individual's medical history and risk factors. Your doctor will recommend the appropriate testing schedule for you.
A blood test poses very little risk. Individuals may experience pain or bruising where the needle was inserted, but most symptoms will subside soon.
The AFP test is not recommended for routine cancer screening in individuals with no symptoms or risk factors. It is generally only used for screening and monitoring in high-risk individuals or those with symptoms.
