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3.1 Minute

14-09-2024 Team Medicover general-medicine

Written by Medicover Team and Medically Reviewed by Dr K Sindhura

Deriphyllin Syrup: Respiratory Relief for Children

Understanding pediatric medications can be challenging for parents and caregivers. One such medication is Deriphyllin syrup, frequently prescribed for respiratory conditions in children. This article aims to provide an in-depth understanding of Deriphyllin syrup, its uses, dosage, and considerations for pediatric use.

What is Deriphyllin Syrup?

Deriphyllin syrup is a combination medication primarily used to treat respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It contains two active ingredients: theophylline and etophylline. These bronchodilators work by relaxing the muscles in the airways, making it easier to breathe.

Theophylline and Etophylline: How They Work

Theophylline, a methylxanthine derivative, exerts its effects by inhibiting phosphodiesterase, leading to an increase in cyclic AMP levels. This results in bronchodilation and reduced airway reactivity. Etophylline, on the other hand, enhances the bronchodilatory effect of theophylline and improves respiratory function.

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Indications for Deriphyllin Syrup in Children

Deriphyllin syrup is commonly prescribed for children with:

Childhood Asthma: It helps manage acute asthma exacerbations and chronic asthma symptoms by easing airway constriction.
Bronchitis: The medication is effective in reducing bronchial inflammation and improving airflow.
Breathing Issues: It can be used for various respiratory conditions that cause breathing difficulties.

Deriphyllin Syrup for Childhood Asthma

Asthma is a prevalent chronic condition among children characterized by recurrent episodes of wheezing, breathlessness, and coughing. Deriphyllin syrup relaxes the bronchial muscles, helping alleviate these symptoms and improve overall lung function. It is often part of a comprehensive asthma management plan that includes other medications and lifestyle modifications.

Dosage and Administration

Deriphyllin Syrup Dosage for Kids

The dosage of Deriphyllin syrup for children is highly individualized and depends on various factors, including the child's age, weight, severity of symptoms, and response to treatment. It is crucial to follow the pediatrician's instructions meticulously.

General Dosage Guidelines

Infants (under one year): Typically, the dosage is calculated based on body weight, usually around 2-3 mg/kg, administered every 6-8 hours.
Children (1-12 years): The usual dose ranges from 4-6 mg/kg, given every 6-8 hours.
Adolescents (12 years and older): The dose may be similar to that of adults, adjusted according to body weight and clinical response.

Administration Tips

Consistent Timing: Administer the syrup at the exact times each day to maintain stable blood levels of the medication.
With or Without Food: Deriphyllin syrup can be given with or without food, but it's best to follow the paediatrician's advice.
Measure Carefully: Use a proper measuring device to ensure accurate dosing.

Side Effects and Precautions

Common Side Effects

Deriphyllin syrup, like any medication, can cause side effects. Common side effects include:

Nausea and Vomiting: Gastrointestinal disturbances are relatively common.
Headache: Some children may experience headaches.
Insomnia: The stimulant effect of theophylline can lead to difficulty sleeping in some cases.

Serious Side Effects

Although rare, serious side effects can occur, such as:

Allergic Reactions: Symptoms like rash, itching, and swelling may indicate an allergy.
Seizures: High doses or rapid increases in dosage can lead to seizures.
Irregular Heartbeat: Theophylline can cause cardiac arrhythmias in susceptible individuals.

Precautions and Contraindications

Allergic Reactions: Ensure the child is not allergic to theophylline, theophylline, or any other component of the syrup.
Medical History: Inform the paediatrician about the child's complete medical history, particularly any cardiac conditions, seizures, or liver problems.
Drug Interactions: Theophylline interacts with various medications. Discuss all current medications and supplements with the paediatrician.

Monitoring and Follow-Up

Regular monitoring of the child's response to Deriphyllin syrup is essential. This includes:

Clinical Assessment: Regular check-ups to assess symptom improvement and detect any adverse effects.
Blood Levels: Periodic measurement of theophylline blood levels to ensure therapeutic levels and avoid toxicity.
Growth and Development: Monitoring growth parameters in children on long-term therapy.

Alternatives and Complementary Therapies

While Deriphyllin syrup is effective, it is not the only option for managing respiratory conditions in children. Alternative and complementary therapies include:

Inhaled Corticosteroids

Inhaled corticosteroids, such as budesonide or fluticasone, are often used as long-term control medications for asthma. They reduce airway inflammation and prevent asthma attacks.

Leukotriene Modifiers

Medications like montelukast block leukotrienes, substances that cause airway constriction and inflammation. They are used as add-on therapy for asthma management.

Non-Pharmacological Interventions

Breathing Exercises: Techniques such as diaphragmatic breathing can help improve lung function.
Environmental Control: Reducing exposure to asthma triggers, such as allergens and pollutants, is crucial.
Nutrition and Hydration: A balanced diet and adequate hydration support overall respiratory health.

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Conclusion

Deriphyllin syrup is a valuable medication for managing respiratory conditions in children. Its bronchodilatory effects make it effective in alleviating symptoms of asthma and other breathing issues. However, careful consideration of dosage, administration, and monitoring is essential to ensure safety and efficacy.

Frequently Asked Questions

Deriphyllin Syrup is used to manage asthma and breathing difficulties in children by relaxing the airways.

Yes, but only under strict medical supervision to treat respiratory issues in infants.

Administer the syrup as prescribed by your pediatrician, usually 2-3 times daily based on the child's weight.

Side effects include drowsiness, dizziness, and stomach upset. Consult your pediatrician if symptoms persist.

Yes, it is effective in managing childhood asthma symptoms by improving airway function and reducing spasms.

Disclaimer:The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.